Search Results - "Sterk, Saskia S"
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Sex hormone-binding globulin regulation of androgen bioactivity in vivo: validation of the free hormone hypothesis
Published in Scientific reports (17-10-2016)“…Sex hormone-binding globulin (SHBG) is the high-affinity binding protein for androgens and estrogens. According to the free hormone hypothesis, SHBG modulates…”
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2
Antiviral drugs in animal-derived matrices: A review
Published in Heliyon (30-09-2024)“…The ban of antiviral drugs in food-producing animals in several parts of the world, latest by Commission Delegated Regulation (EU) 2022/1644, has increased the…”
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Distinction of clenbuterol intake from drug or contaminated food of animal origin in a controlled administration trial - the potential of enantiomeric separation for doping control analysis
Published in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (03-04-2017)“…The differentiation of clenbuterol abuse and unintentional ingestion from contaminated meat is crucial with respect to the valuation of an adverse analytical…”
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Enhanced UHPLC-MS/MS screening of selective androgen receptor modulators following urine hydrolysis
Published in MethodsX (01-01-2020)“…[Display omitted] Selective androgen receptor modulators (SARMs) represent non-steroidal agents commonly abused in human and animal (i.e. equine, canine)…”
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Detection of anabolic androgenic steroid abuse in doping control using mammalian reporter gene bioassays
Published in Analytica chimica acta (01-04-2009)“…Anabolic androgenic steroids (AAS) are a class of steroid hormones related to the male hormone testosterone. They are frequently detected as drugs in sport…”
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Towards high throughput analysis using 96-well plate solid phase extraction to determine sedatives and β-blocker residues in food control monitoring
Published in Analytica chimica acta (01-12-2024)“…Veterinary drugs are widely used in animal production to prevent infections and treat diseases but, this may cause a risk to consumers. Due to the high number…”
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Development and validation of a semi-quantitative ultra-high performance liquid chromatography-tandem mass spectrometry method for screening of selective androgen receptor modulators in urine
Published in Journal of Chromatography A (30-08-2019)“…•Rapid multi-residue UHPLC-MS/MS assay developed for important SARM compounds.•15 SARMs from several families screened semi-quantitatively in urine test…”
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USB-Powered Coated Blade Spray Ion Source for On-Site Testing Using Transportable Mass Spectrometry
Published in Journal of the American Society for Mass Spectrometry (04-11-2020)“…On-site testing in food analysis using mass spectrometry (MS) requires miniaturization of vacuum systems, mass analyzers, sample cleanup, and ionization…”
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Simultaneous determination of five metabolites of nitrofurans including the metabolite nifursol in shrimp and fish by UPLC- MS/MS: in-house method validation according to commission implementing regulation (EU) 2021/808
Published in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (01-02-2023)“…For the simultaneous identification and quantification of five nitrofurans metabolites in farmed shrimp and fish, 3-amino-2-oxazolidinone (AOZ),…”
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Discrimination between the exogenous and endogenous origin of thiouracil in farm animals, the final chapter?
Published in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (02-12-2021)“…Thiouracil (2-thiouracil) is a thyreostatic compound that can be used as an illegal growth promoter. In bovine, porcine and other farm animals, low…”
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Toward a New European Threshold to Discriminate Illegally Administered from Naturally Occurring Thiouracil in Livestock
Published in Journal of agricultural and food chemistry (11-02-2015)“…Thiouracil is a thyrostat inhibiting the thyroid function, resulting in fraudulent weight gain if applied in the fattening of livestock. The latter abuse is…”
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12
Adverse analytical findings with clenbuterol among U-17 soccer players attributed to food contamination issues
Published in Drug testing and analysis (01-05-2013)“…The illicit use of growth promoters in animal husbandry has frequently been reported in the past. Among the drugs misused to illegally increase the benefit of…”
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A view on the analytical design of future risk based residue control
Published in Drug testing and analysis (01-05-2016)“…The current laboratory network system in support of residue monitoring programmes within the EU formally started in the early 1990s. Since then, it has…”
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Ultratrace LC-MS/MS Analysis of Segmented Calf Hair for Retrospective Assessment of Time of Clenbuterol Administration in Agriforensics
Published in Journal of agricultural and food chemistry (21-01-2015)“…In agriforensics, time of administration is often debated when illegal drug residues, such as clenbuterol, are found in frequently traded cattle. In this…”
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Determination and confirmation of selective estrogen receptor modulators (SERMs), anti-estrogens and aromatase inhibitors in bovine and porcine urine using UHPLC-MS/MS
Published in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (03-04-2017)“…Selective estrogen receptor modulators (SERMs), anti-estrogens and aromatase inhibitors are prohibited in human sports doping. However, they also present a…”
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Evaluation of the Discriminative Potential of a Novel Biomarker for Estradiol Treatments in Bovine Animals
Published in Journal of agricultural and food chemistry (14-01-2015)“…The endogenous occurrence of natural hormones obstructs the application of classical targeted methods as confirmatory options. In the case of estradiol, the…”
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Investigation of the presence of prednisolone in bovine urine
Published in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (03-04-2014)“…Over the past two years low levels of prednisolone have been reported in bovine urine by a number of laboratories in European Union member states…”
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Confirmation and 3D profiling of anabolic steroid esters in injection sites using imaging desorption electrospray ionisation (DESI) mass spectrometry
Published in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (01-06-2013)“…In this study, desorption electrospray ionisation (DESI) linear ion trap tandem mass spectrometry (MS n ) was applied for the confirmation and…”
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Journal Article Conference Proceeding -
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Selective androgen receptor modulators: in vitro and in vivo metabolism and analysis
Published in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (01-09-2013)“…For future targeted screening in National Residue Control Programmes, the metabolism of seven SARMs, from the arylpropionamide and the quinolinone classes, was…”
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Evolution and revolutions in the control system for residues of veterinary substances in food-producing animals over more than three decades
Published in Food control (01-07-2023)Get full text
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