Search Results - "Sterjev, Z"
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Co-Existence of CYP2C191/2 and ABCB1c.3435 CT Genotype has a Potential Impact on Clinical Outcome in CAD Patients Treated with Clopidogrel
Published in Balkan journal of medical genetics (01-12-2023)“…Clopidogrel, is a standard treatment in the prevention of major adverse cardiovascular events (MACE) in patients with coronary artery disease (CAD)…”
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Influence of potential gene polymorphisms on propofol dosage regimen in patients undergoing abdominal hysterectomy
Published in Balkan journal of medical genetics (23-03-2021)“…Propofol (2,6-diisopropylphenol) is the most common intravenous anesthetic used in modern medicine. It is postulated that individual differences in genetic…”
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Treatment in Transplant Eligible Multiple Myeloma Patients in Macedonia: Development of Cost-Effectiveness Analysis
Published in Value in health (01-10-2017)“…OBJECTIVES: We developed a decision-analytic model to study the impact of the three induction regimens: Vincristine-Adriamycin-Dexarnethasone (VAD),…”
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Impact of biosimilar medicinal products in the EU pharmaceutical market
Published in Clinical therapeutics (01-08-2015)“…Even though the most important conditions for market uptake of biosimilars are driven by commercial factors, still, real clinical evidence, clear regulatory…”
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Distribution of the Most Common Genetic Variants Associated with a Variable Drug Response in the Population of the Republic of Macedonia
Published in Balkan journal of medical genetics (01-12-2014)“…Genetic variation in the regulation, expression and activity of genes coding for Phase I, Phase II drug metabolizing enzymes (DMEs) and drug targets, can be…”
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Pharmacogenetics and antipsychotic treatment response
Published in Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki) (2015)“…Antipsychotic drugs are widely used in the treatment of schizophrenia and psychotic disorder. The lack of antipsychotic response and treatment-induced…”
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The Effects of the New Methodology Application on the Method of Pricing of Drugs—The Case of the Republic of Macedonia
Published in Value in health regional issues (01-09-2016)“…Background: The introduction of a new methodology for the pricing of drugs by the Agency of Medicines of the Republic of Macedonia for the period 2012 to 2015…”
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Influence of the SCN1A IVS5N + 5 G>A Polymorphism on Therapy with Carbamazepine for Epilepsy
Published in Balkan journal of medical genetics (01-01-2012)“…Carbamazepine (CBZ) blocks neuronal sodium channels in a voltage- and frequency-dependent manner, delaying the recovery of the channels from the inactivated…”
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Methylenetetrahydrofolate Reductase C677T Polymorphism and Risk of Colorectal Cancer in the Macedonian Population
Published in Balkan journal of medical genetics (01-01-2008)“…Methylenetetrahydrofolate reductase (MTHFR) regulates the flow of folate groups between DNA synthesis and DNA methylation. A common C677T substitution…”
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Cyclin D1 G870A Variant is Associated with Increased Risk of Microsatellite Instability-Positive Colorectal Cancer in Young Male Patients
Published in Balkan journal of medical genetics (01-01-2007)“…Cyclin D1 (CCND1) is a cell cycle regulatory protein, which is often over expressed in human tumors and is associated with cell proliferation and poor…”
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Co-Existence of CYP2C19 1/2 and ABCB1c .3435 CT Genotype has a Potential Impact on Clinical Outcome in CAD Patients Treated with Clopidogrel
Published in Balkan journal of medical genetics (01-12-2023)“…Clopidogrel, is a standard treatment in the prevention of major adverse cardiovascular events (MACE) in patients with coronary artery disease (CAD)…”
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PRM34 - Cost –Effectiveness of Obinutuzumab As Frontline Treatment For Unfit Patients With Chronic Lymphocytic Leukemia In Republic of Macedonia
Published in Value in health (01-10-2017)Get full text
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Pharmacoeconomic Evaluation of Sorafenib As First-Line Treatment for Advanced Hepatocellular Carcinoma
Published in Value in health (01-10-2017)“…OBJECTIVES: Sorafenib significantly improve the overall survival of patients with advanced hepatocellular carcinoma (HCC). Conducted research aimed to assess…”
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PRM36 - Pharmacoeconomic Evaluation of Sorafenib As First-Line Treatment for Advanced Hepatocellular Carcinoma
Published in Value in health (01-10-2017)Get full text
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PCN128 - Treatment in Transplant Eligible Multiple Myeloma Patients in Macedonia: Development of Cost-Effectiveness Analysis
Published in Value in health (01-10-2017)Get full text
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Cost –Effectiveness of Obinutuzumab As Frontline Treatment For Unfit Patients With Chronic Lymphocytic Leukemia In Republic of Macedonia
Published in Value in health (01-10-2017)“…OBJECTIVES: According to the results from the CLL-11 trial, obinutuzumab+ chlorambucil (G-Clb) is superior to rituximab+chlorambucil (R-Clb) leading to an 13.8…”
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Evaluation of reliability and validity of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30, Albanian version) among breast cancer patients from Kosovo
Published in Patient preference and adherence (01-01-2015)“…A sample of breast cancer patients (n=62 women) were interviewed for the European Organization for Research and Treatment of Cancer Quality of Life…”
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PCN188 - Subcutaneous Vs Intravenous Administration Of Trastuzumab In Her2+ Breast Cancer Patients: A Macedonian Cost-Minimization Analysis
Published in Value in health (01-11-2015)Get full text
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Subcutaneous Vs Intravenous Administration Of Trastuzumab In Her2+ Breast Cancer Patients: A Macedonian Cost-Minimization Analysis
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