Search Results - "Stepovaya, E A"

Heat Shock Protein HSP27 and the Status of the Glutathione System in Dexamethasone-Induced Apoptosis of Jurkat Tumor Cells by Nosareva, O. L., Stepovaya, E. A., Litvinova, L. S., Yurova, K. A.

“…We studied the effect of the HSP27 inhibitor, 5-(5-ethyl-2-hydroxy-4-methoxyphenyl)-4-(4-methoxyphenyl)-isoxazole, at a final concentration of 0.1 μM and/or…”
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Role of oxidative modification of proteins in the regulation and realization of cell death of blood lymphocytes under the conditions of blocking glutathione synthesis under oxidative stress by Nosareva, O. L., Stepovaya, E. A.

“…Lymphocytes are key cells in inflammation. The realization of inflammation accompanied by the development of oxidative stress depends on metabolic processes…”
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Neural Crest of the Human Embryo: Development, Structure, and Derivatives (Data of Morphological Studies) by Milto, I. V., Ivanova, V. V., Serebrjakova, O. N., Klimentyeva, T. K., Stepovaya, E. A., Sukhodolo, I. V.

“…The neural crest of the human embryo is a structure that has been studied for a long time. However, the information about this structure is not well…”
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The Role of Redox Status Changes in Dexamethasone-Induced Apoptosis in Jurkat Tumor Cells by Nosareva, О. L., Stepovaya, E. A., Shakhristova, E. V., Karpov, R. M.

“…The apoptotic death and its regulation was studied in intact Jurkat tumor cells and under the influence of buthionine-sulfoximine ( de novo glutathione…”
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Oxidative Modification of Redox Proteins: Role in the Regulation of HBL-100 Cell Proliferation by Shakhristova, E. V., Stepovaya, E. A., Rudikov, E. V., Novitskii, V. V.

“…HBL-100 breast epithelial cells were cultured with a blocker (N - ethylmaleimide) and protector (1,4-dithioerythritol) of SH groups. The study assessed changes…”
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Molecular mechanisms of the effects of N-ethylmaleimide and 1,4-dithioerythritol on regulation of apoptosis in P19 cells under hypoxia by Nosareva, O. L., Orlov, D. S., Shakhristova, E. V., Stepovaya, E. A.

“…Relevance. Impairment of apoptosis regulation in P19 cells is correlated with generation of oxidative stress. Under hypoxia, changes in mitochondrial functions…”
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Role of Thiol-Disulfide System in Mechanisms of Functional Changes in Neutrophils under Conditions of Oxidative Stress by Stepovaya, E. A, Petina, G. V, Zhavoronok, T. V, Ryazanceva, N. V, Ivanov, V. V, Ageeva, T. S, Tetenev, F. F, Novitsky, V. V

“…We studied the state of the thiol-disulfide system (contents of reduced and oxidized glutathione, their ratio, and concentrations of protein SH-groups and…”
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EFFECT OF N-ACETYLCYSTEINE ON APOPTOSIS OF P19 CANCER CELLS DURING HYPOXIA by Nosareva, O. L., Orlov, D. S., Shakhristova, E. V., Stepovaya, E. A., Sadykova, A. A.

“…Introduction. Hypoxia in tumor growth contributes to mitochondrial dysfunction and exacerbates oxidative stress in the immortalized cell. The objective of the…”
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The Role of the Glutathione System in Oxidative Modification of Proteins and Dysregulation of Apoptosis in Jurkat Tumor Cells by Nosareva, O. L., Stepovaya, E. A., Ryazantseva, N. V., Shakhristova, E. V., Egorova, M. Yu, Novitsky, V. V.

“…We compared changes in the redox status and intensity of oxidative modification of proteins in intact Jurkat tumor cells and cells cultured with buthionine…”
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Protein carbonylation as a possible way to modulate breast cancer cell proliferation by Shakhristova, E. V., Stepovaya, E. A., Sadykova, A. A., Novitsky, V. V.

“…Introduction. High rates of cancer incidence and mortality worldwide dictate the necessity of developing new methodological approaches in understanding the…”
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Forms of pseudotuberculosis progression in children and the impact of lipid peroxidation activation and antioxidant system imbalance on their development by Pomogaeva, A. P., Nosareva, O. L., Stepovaya, E. A., Zhavoronok, T. V., Shakhristova, E. V., Krasnova, E. I., Vasyunin, A. V.

“…The objective is to compare clinical symptoms, lipid peroxidation indicators, the state of the antioxidant system and assess their impact on the severity and…”
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Ubiquitin and regulation of apoptosis in Jurkat cells by Nosareva, O. L., Stepovaya, E. A., Ryazantseva, N. V., Shakhristova, E. V., Orlov, D. S., Novitsky, V. V.

“…Introduction. One of the crucial tasks in medicine is studying the molecular mechanisms of selective management of tumor cell apoptosis following…”
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Effect of insulin, the glutathione system, and superoxide anion radical in modulation of lipolysis in adipocytes of rats with experimental diabetes by Ivanov, V. V., Shakhristova, E. V., Stepovaya, E. A., Nosareva, O. L., Fedorova, T. S., Ryazantseva, N. V., Novitsky, V. V.

“…Spontaneous lipolysis was found to be increased in adipocytes of rats with alloxan-induced diabetes. In addition, isoproterenol-stimulated hydrolysis of…”
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Role of Glutathione System Redox Potential in Apoptosis Dysregulation in MCF-7 Breast Adenocarcinoma by Shakhristova, E. V., Stepovaya, E. A., Ryazantseva, N. V., Nosareva, O. L., Yakushina, V. D., Ivanov, V. V., Novitskii, V. V.

“…MCF-7 breast cancer cells and HBL-100 breast epithelial cells were cultured with N-ethylmaleimide, a blocker of SH groups. Changes in redox potential of the…”
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A multi-centre study on the role of the thioredoxin system in breast cancer cell proliferation by Shakhristova, E. V., Stepovaya, E. A., Nosareva, O. L., Litvinova, L. S., Skuratovskaya, D. A., Rudikov, E. V., Sadykova, A. A., Novitsky, V. V.

“…Redox proteins (thioredoxin, glutaredoxin) are key macromolecules capable of modulating intracellular processes. This determines research choices in the field…”
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Redox-dependent mechanisms of regulation of breast epithelial cell proliferation by Stepovaya, E. A., Shakhristova, E. V., Nosareva, O. L., Rudikov, E. V., Egorova, M. Yu, Egorova, D. Yu, Novitsky, V. V.

“…Activation of free radical oxidation in various types of cells, including breast epithelial cells, can lead to damage to macromolecules, particularly proteins…”
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MECHANISMS OF APOPTOSIS DYSREGULATION IN CANCER CELLS UNDER THE CONDITIONS OF REDOX STATUS MODULATION by Orlov, D. S., Ryazantseva, N. V., Stepovaya, E. A., Nosareva, O. L., Shakhristova, E. V., Ivanov, V. V.

“…Introduction. Changes in the redox status of tumor cells can be used as one of the molecular mechanisms of apoptosis aimed at increasing the susceptibility of…”
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The role of protein oxidative modification and the cellular redox status in realization of apoptosis of MCF-7 breast adenocarcinoma cells by Shakhristova, E. V., Stepovaya, E. A., Ryazantseva, N. V., Nosareva, O. L., Yakushina, V. D., Ivanov, V. V., Novitsky, V. V.

“…The aim of this study was to establish the role of oxidative modification of proteins and redox status in the realization of apoptosis of MCF-7 breast…”
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THE THIOREDOXIN SYSTEM IN REGULATING MCF-7 CELL PROLIFERATION UNDER REDOX STATUS MODULATION by Stepovaya, E. A., Shakhristova, E. V., Ryazantseva, N. V., Nosareva, O. L., Chil’chigashev, R. I., Egorova, M. Yu

“…Introduction. Despite the available data on tumor cell functioning under the conditions of free radical-mediated oxidation, the mechanisms of redox regulation,…”
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The role of oxidative protein modification and the glutathione system in modulation of the redox status of breast epithelial cells by Stepovaya, E. A., Shakhristova, E. V., Ryazantseva, N. V., Nosareva, O. L., Yakushina, V. D., Nosova, A. I., Gulaya, V. S., Stepanova, E. A., Chil’chigashev, R. I., Novitsky, V. V.

“…The effects of N-ethylmaleimide (NEM) and 1,4-dithioerythritol (DTE) on the level of oxidative modification of proteins, the state of glutathione and…”
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