Search Results - "Stephenson, Sophie J"

Early Emergence of CD19-Negative Human Antibody-Secreting Cells at the Plasmablast to Plasma Cell Transition by Arumugakani, Gururaj, Stephenson, Sophie J, Newton, Darren J, Rawstron, Andy, Emery, Paul, Doody, Gina M, McGonagle, Dennis, Tooze, Reuben M

“…Long-lived human plasma cells (PCs) play central roles in immunity and autoimmunity and are enriched among the subpopulation of CD19 human PCs. However,…”
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Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity by Care, Matthew A, Stephenson, Sophie J, Barnes, Nicholas A, Fan, Im, Zougman, Alexandre, El-Sherbiny, Yasser M, Vital, Edward M, Westhead, David R, Tooze, Reuben M, Doody, Gina M

“…Plasma cells (PCs) as effectors of humoral immunity produce Igs to match pathogenic insult. Emerging data suggest more diverse roles exist for PCs as…”
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Amino Acid Deprivation Links BLIMP-1 to the Immunomodulatory Enzyme Indoleamine 2,3-Dioxygenase by Barnes, Nicholas A, Stephenson, Sophie J, Tooze, Reuben M, Doody, Gina M

“…Catabolism of tryptophan by IDO1 plays an important role in the control of immune responses. Activation of the eukaryotic initiation factor 2alpha (eIF2alpha)…”
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Interaction surface of the Spo0A response regulator with the Spo0E phosphatase by Stephenson, Sophie J., Perego, Marta

“…Summary Spo0A~P is the essential response regulator and transcription factor for sporulation initiation in Bacillus subtilis. The phosphorylation level of…”
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APRIL signaling in human antibody secreting cells promotes cellular response via p38 and differential immediate early gene regulation by Stephenson, Sophie J, Care, Matthew A, Doody, Gina M, Tooze, Reuben M

“…Long-lived antibody secreting cells (ASCs) persist as quiescent plasma cells (PCs) in niche microenvironments. However, we know little about how ASCs integrate…”
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A screening platform for human plasma cells (PCs) reveals a selective response to SYK inhibition by Campbell, Michelle, Stephenson, Sophie J, Whale, Kevin, Rapecki, Stephen, Finney, Helene, Doody, Gina M, Tooze, Reuben M

“…Therapeutic targeting of PC populations has potential value in various auto-immune, allergic and neoplastic cell states, but at present few options exist for…”
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Interaction surface of the SpoOA response regulator with the SpoOE phosphatase by Stephenson, Sophie J, Perego, Marta

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