Search Results - "Stephenson, Joseph"

Pilot Study Using Molecular Profiling of Patients' Tumors to Find Potential Targets and Select Treatments for Their Refractory Cancers by VON HOFF, Daniel D, STEPHENSON, Joseph J, FITCH, Tom R, WASSERMAN, Ernesto, FERNANDEZ, Cristian, GREEN, Sylvan, SUTHERLAND, William, BITTNER, Michael, ALARCON, Arlet, MALLERY, David, PENNY, Robert, ROSEN, Peter, LOESCH, David M, BORAD, Mitesh J, ANTHONY, Stephen, JAMESON, Gayle, BROWN, Susan, CANTAFIO, Nina, RICHARDS, Donald A

“…To compare the progression-free survival (PFS) using a treatment regimen selected by molecular profiling (MP) of a patient's tumor with the PFS for the most…”
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Review of Shakespeare's King Lear (Directed by Helena Kaut-Howson) at Shakespeare's Globe, London, 1 June and 24 July 2022 by Stephenson, Joseph F.

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Combination Dabrafenib and Trametinib Versus Combination Nivolumab and Ipilimumab for Patients With Advanced BRAF -Mutant Melanoma: The DREAMseq Trial-ECOG-ACRIN EA6134 by Atkins, Michael B, Lee, Sandra J, Chmielowski, Bartosz, Tarhini, Ahmad A, Cohen, Gary I, Truong, Thach-Giao, Moon, Helen H, Davar, Diwakar, O'Rourke, Mark, Stephenson, Joseph J, Curti, Brendan D, Urba, Walter J, Brell, Joanna M, Funchain, Pauline, Kendra, Kari L, Ikeguchi, Alexandra P, Jaslowski, Anthony, Bane, Charles L, Taylor, Mark A, Bajaj, Madhuri, Conry, Robert M, Ellis, Robert J, Logan, Theodore F, Laudi, Noel, Sosman, Jeffrey A, Crockett, David G, Pecora, Andrew L, Okazaki, Ian J, Reganti, Sowjanya, Chandra, Sunandana, Guild, Samantha, Chen, Helen X, Streicher, Howard Z, Wolchok, Jedd D, Ribas, Antoni, Kirkwood, John M

“…Combination programmed cell death protein 1/cytotoxic T-cell lymphocyte-4-blockade and dual BRAF/MEK inhibition have each shown significant clinical benefit in…”
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Review of Shakespeare's Measure for Measure (Directed by Blanche McIntyre for Shakespeare's Globe) at the Sam Wanamaker Playhouse, London, 10 December 2021 by Stephenson, Joseph F.

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Review of Shakespeare's Twelfth Night (Directed by Sean Holmes) at Shakespeare's Globe, London, 6 and 7 August 2021 by Stephenson, Joseph F.

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A first in human phase 1 study of CG0070, a GM-CSF expressing oncolytic adenovirus, for the treatment of nonmuscle invasive bladder cancer by Burke, James M, Lamm, Donald L, Meng, Maxwell V, Nemunaitis, John J, Stephenson, Joseph J, Arseneau, James C, Aimi, Junko, Lerner, Seth, Yeung, Alex W, Kazarian, Troy, Maslyar, Daniel J, McKiernan, James M

“…We assessed the safety, pharmacokinetics and anticancer activity of intravesical CG0070, a cancer selective, replication competent adenovirus, for the…”
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Automated detection of lung nodules and coronary artery calcium using artificial intelligence on low-dose CT scans for lung cancer screening: accuracy and prognostic value by Chamberlin, Jordan, Kocher, Madison R, Waltz, Jeffrey, Snoddy, Madalyn, Stringer, Natalie F C, Stephenson, Joseph, Sahbaee, Pooyan, Sharma, Puneet, Rapaka, Saikiran, Schoepf, U Joseph, Abadia, Andres F, Sperl, Jonathan, Hoelzer, Phillip, Mercer, Megan, Somayaji, Nayana, Aquino, Gilberto, Burt, Jeremy R

“…Artificial intelligence (AI) in diagnostic radiology is undergoing rapid development. Its potential utility to improve diagnostic performance for…”
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Androgen Receptor Modulation Optimized for Response (ARMOR) Phase I and II Studies: Galeterone for the Treatment of Castration-Resistant Prostate Cancer by Montgomery, Bruce, Eisenberger, Mario A, Rettig, Matthew B, Chu, Franklin, Pili, Roberto, Stephenson, Joseph J, Vogelzang, Nicholas J, Koletsky, Alan J, Nordquist, Luke T, Edenfield, William J, Mamlouk, Khalid, Ferrante, Karen J, Taplin, Mary-Ellen

“…Galeterone is a selective, multitargeted agent that inhibits CYP17, antagonizes the androgen receptor (AR), and reduces AR expression in prostate cancer cells…”
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Review of Shakespeare's Henry VI and Richard III (directed by Sean Holmes and Ilinca Radulian for Shakespeare's Globe) at the Sam Wanamaker Playhouse, London, 22 January (Matinée) and 23 January 2020 by Stephenson, Joseph F.

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Review of Shakespeare's Macbeth (directed by Robert Hastie for Shakespeare's Globe) at the Sam Wanamaker Playhouse, London, 10 January and 12 January (Matinée) 2019 by Stephenson, Joseph F.

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Review of Webster's The Duchess of Malfi (directed by Maria Aberg for the Royal Shakespeare Company) at the Swan Theatre, Stratford-upon-Avon, 13 March 2018, and Lyly's The Woman in the Moon (directed by Perry Mills for Edward's Boys) at Levi Fox Hall, King Edward VI School, 11 March 2018 by Stephenson, Joseph F.

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A New Source for Two Aphra Behn Plays: The Dutch Lady, A Restoration Comedy in Manuscript by Stephenson, Joseph F., Freebury-Jones, Darren

“…Stephenson and Freebury-Jones discuss the manuscript of an unpublished and previously unstudied Restoration comedy, The Dutch Lady. Based on evidence found via…”
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Effects of ketoconazole and esomeprazole on the pharmacokinetics of pazopanib in patients with solid tumors by Tan, Antoinette R., Gibbon, Darlene G., Stein, Mark N., Lindquist, Diana, Edenfield, Jeffery W., Martin, Julie C., Gregory, Charles, Suttle, A. Benjamin, Tada, Hiroomi, Botbyl, Jeffrey, Stephenson, Joseph J.

“…Purpose The metabolism of pazopanib is primarily mediated by CYP3A4. The solubility of pazopanib is pH-dependent, and an elevated gastric pH may decrease its…”
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Discovery of Nanomolar-Affinity Pharmacological Chaperones Stabilizing the Oncogenic p53 Mutant Y220C by Stephenson Clarke, Joseph R., Douglas, Leon R., Duriez, Patrick J., Balourdas, Dimitrios-Ilias, Joerger, Andreas C., Khadiullina, Raniya, Bulatov, Emil, Baud, Matthias G. J.

“…The tumor suppressor protein p53 is inactivated in the majority of human cancers and remains a prime target for developing new drugs to reactivate its tumor…”
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Association Between Birth Weight Z-Scores and Early Outcomes Following Truncus Arteriosus Repair by Stephenson, Joseph J., Hook, Jessica E., Beall, Jonathan, Delany, Dennis R., Buckley, Jason R., Chowdhury, Shahryar M., Steurer, Martina A., Kavarana, Minoo N., Costello, John M.

“…In infants undergoing truncus arteriosus (TA) repair, we sought to determine associations between fetal growth restrictions as measured by birth weight Z-score…”
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Correction to: Association Between Birth Weight Z-Scores and Early Outcomes Following Truncus Arteriosus Repair by Stephenson, Joseph J., Hook, Jessica E., Beall, Jonathan, Delany, Dennis R., Buckley, Jason R., Chowdhury, Shahryar M., Steurer, Martina A., Kavarana, Minoo N., Costello, John M.

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Tumor burden of lung metastases at initial staging in breast cancer patients detected by artificial intelligence as a prognostic tool for precision medicine by Kocher, Madison R., Chamberlin, Jordan, Waltz, Jeffrey, Snoddy, Madalyn, Stringer, Natalie, Stephenson, Joseph, Kahn, Jacob, Mercer, Megan, Baruah, Dhiraj, Aquino, Gilberto, Kabakus, Ismail, Hoelzer, Philipp, Sahbaee, Pooyan, Schoepf, U. Joseph, Burt, Jeremy R.

“…Determination of the total number and size of all pulmonary metastases on chest CT is time-consuming and as such has been understudied as an independent metric…”
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Redefining the Dutch: Dryden's Appropriation of National Images from Renaissance Drama in "Amboyna" by Stephenson, Joseph F.

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Key Players in the Mutant p53 Team: Small Molecules, Gene Editing, Immunotherapy by Chasov, Vitaly, Mirgayazova, Regina, Zmievskaya, Ekaterina, Khadiullina, Raniya, Valiullina, Aygul, Stephenson Clarke, Joseph, Rizvanov, Albert, Baud, Matthias G. J., Bulatov, Emil

“…The transcription factor p53 is a key tumor suppressor that is inactivated in almost all cancers due to either point mutations in the TP53 gene or…”
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Phase I Clinical Study of Seneca Valley Virus (SVV-001), a Replication-Competent Picornavirus, in Advanced Solid Tumors with Neuroendocrine Features by RUDIN, Charles M, POIRIER, John T, SENZE, Neil N, STEPHENSON, Joseph, LOESCH, David, BURROUGHS, Kevin D, SESHIDHAR REDDY, P, HANN, Christine L, HALLENBECK, Paul L

“…Seneca Valley Virus (SVV-001) is a novel naturally occurring replication-competent picornavirus with potent and selective tropism for neuroendocrine cancer…”
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