Search Results - "Stephenson, H A"

ATP: the red blood cell link to NO and local control of the pulmonary circulation by Sprague, R S, Ellsworth, M L, Stephenson, A H, Lonigro, A J

“…Recently, we reported that rabbit red blood cells (RBCs) were required for the expression of nitric oxide (NO) activity on pulmonary vascular resistance (PVR)…”
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Analysis of the interactions of Nrf-2, PMF-1, and CSN-7 with the 5′-flanking sequence of the mouse 4E-BP1 gene by Stephenson, A.H., Seidel, E.R.

“…Nuclear factor erythroid 2-related factor 2 (Nrf-2) binds to a specific polyamine responsive element (PRE) in the promoter region of the spermidine–spermine…”
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Polyamines regulate eukaryotic initiation factor 4E-binding protein 1 gene transcription by Stephenson, A.H., Christian, J.F., Seidel, E.R.

“…Difluoromethylornithine-induced polyamine depletion produced a significant fall in the rate of 4E-BP1 gene transcription in IEC-6 cells, without a change in…”
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The Rho kinase inhibitor Y-27632 increases erythrocyte deformability and low oxygen tension-induced ATP release by Thuet, K M, Bowles, E A, Ellsworth, M L, Sprague, R S, Stephenson, A H

“…Low oxygen (O(2)) tension and mechanical deformation are stimuli for ATP release from erythrocytes. It has been shown previously that rabbit erythrocytes made…”
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Role of cyclooxygenase-2 in oleic acid-induced acute lung injury by GUST, R, KOZLOWSKI, J. K, STEPHENSON, A. H, SCHUSTER, D. P

“…Eicosanoid production appears to be important to both edemagenesis and the pattern of pulmonary perfusion in experimental acute lung injury (ALI). We…”
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Effect of L-NAME on pressure-flow relationships in isolated rabbit lungs: role of red blood cells by Sprague, R S, Stephenson, A H, Dimmitt, R A, Weintraub, N L, Branch, C A, McMurdo, L, Lonigro, A J, Weintraub, N A

“…Nitric oxide (NO) is produced by and relaxes pulmonary arteries and veins; however, a role for NO as a participant in the control of pulmonary vascular…”
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Synergistic hemodynamic effects of low-dose endotoxin and acute lung injury by GUST, R, KOZLOWSKI, J, STEPHENSON, A. H, SCHUSTER, D. P

“…We evaluated the effects of low-dose endotoxin (15 microg/kg) on the pulmonary and systemic responses to oleic acid (OA)-induced acute lung injury in dogs…”
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The adenovirus E3-14.7K protein and the E3-10.4K/14.5K complex of proteins, which independently inhibit tumor necrosis factor (TNF)-induced apoptosis, also independently inhibit TNF-induced release of arachidonic acid by Krajcsi, P, Dimitrov, T, Hermiston, T W, Tollefson, A E, Ranheim, T S, Vande Pol, S B, Stephenson, A H, Wold, W S

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Response to inhaled nitric oxide in acute lung injury depends on distribution of pulmonary blood flow prior to its administration by GUST, R, MCCARTHY, T. J, KOZLOWSKI, J, STEPHENSON, A. H, SCHUSTER, D. P

“…Responses to inhaled nitric oxide (iNO) in acute lung injury (ALI), as evidenced by improvements in oxygenation, are variable. We hypothesized that the effect…”
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Effect of eicosanoid inhibition on the development of pulmonary edema after acute lung injury by Schuster, D P, Stephenson, A H, Holmberg, S, Sandiford, P

“…In experimental models of acute lung injury, cyclooxygenase inhibition improves oxygenation, presumably by causing a redistribution of blood flow away from…”
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Inhibition of cytochrome P-450 attenuates hypoxemia of acute lung injury in dogs by Stephenson, A H, Sprague, R S, Weintraub, N L, McMurdo, L, Lonigro, A J

“…The intravenous administration of ethchlorvynol (ECV), in dogs, resulted in an acute lung injury (ALI) characterized by a 200 +/- 80% increase in venous…”
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Thromboxane receptor stimulation/inhibition and perfusion redistribution after acute lung injury by Schuster, D P, Sandiford, P, Stephenson, A H

“…Perfusion redistribution (PR) after acute oleic acid (OA) lung injury may be the result of changes in the tissue concentration ratio of thromboxane (Tx) and…”
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Participation of cAMP in a signal-transduction pathway relating erythrocyte deformation to ATP release by Sprague, R S, Ellsworth, M L, Stephenson, A H, Lonigro, A J

“…Previously, we reported that red blood cells (RBCs) of rabbits and humans release ATP in response to mechanical deformation and that this release of ATP…”
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Relationship of Arachidonic Acid Release to Porcine Coronary Artery Relaxation by Weintraub, Neal L, Stephenson, Alan H, Sprague, Randy S, McMurdo, Lorraine, Lonigro, Andrew J

“…In porcine coronary artery endothelium-dependent relaxation to bradykinin is in part attributed to a chemically unidentified factor, termed endothelium-derived…”
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Vascular endothelial growth factor mRNA in pericytes is upregulated by phorbol myristate acetate by YANG KIM, IMDAD, R. Y, STEPHENSON, A. H, SPRAGUE, R. S, LONIGRO, A. J

“…Increased microvascular permeability, which occurs in conditions such as the adult respiratory distress syndrome and diabetes mellitus, is related to…”
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Deformation-induced ATP release from red blood cells requires CFTR activity by Sprague, R S, Ellsworth, M L, Stephenson, A H, Kleinhenz, M E, Lonigro, A J

“…Recently, it was reported that rabbit and human red blood cells (RBCs) release ATP in response to mechanical deformation. Here we investigate the hypothesis…”
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Eicosanoid balance and perfusion redistribution of oleic acid-induced acute lung injury by Stephenson, A H, Lonigro, A J, Holmberg, S W, Schuster, D P

“…We have proposed that endogenous prostacyclin opposes the vasoconstriction responsible for redistribution of regional pulmonary blood flow (rPBF) away from…”
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OKY-046 prevents increases in LTB4 and pulmonary edema in phorbol ester-induced lung injury in dogs by Sprague, R S, Stephenson, A H, Lonigro, A J

“…Thromboxanes (Txs) were implicated as possible participants in the altered microvascular permeability of acute lung injury when the Tx synthase inhibitor,…”
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Enhanced microvascular permeability of PMA-induced acute lung injury is not mediated by cyclooxygenase products by Wurtz, M M, Stephenson, A H, Sprague, R S, Lonigro, A J

“…Products of cyclooxygenase activity have been proposed to mediate the pulmonary hypertension and increased microvascular permeability associated with phorbol…”
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Hypotheses regarding the role of pericytes in regulating movement of fluid, nutrients, and hormones across the microcirculatory endothelial barrier by Lonigro, A J, McMurdo, L, Stephenson, A H, Sprague, R S, Weintraub, N L

“…A decade ago, we initiated studies to define relationship(s) between products of 5-lipoxygenase-mediated arachidonic acid metabolism and altered microvascular…”
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