Search Results - "Stephens, Paul"
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Repair of Total Anomalous Pulmonary Venous Connection: Risk Factors for Postoperative Obstruction
Published in The Annals of thoracic surgery (01-07-2019)“…Pulmonary venous obstruction after repair of total anomalous pulmonary venous connection (TAPVC) results in substantial morbidity and mortality. Risk factors…”
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Penetrating wood foreign bodies (stob) of the coronary band in horses: 15 cases
Published in Journal of the American Veterinary Medical Association (01-08-2024)“…To retrospectively report the historical and clinical findings, diagnostics, treatment, and outcome of horses with penetrating wood foreign bodies (PWFBs) of…”
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Chromatin function modifying elements in an industrial antibody production platform--comparison of UCOE, MAR, STAR and cHS4 elements
Published in PloS one (07-04-2015)“…The isolation of stably transfected cell lines suitable for the manufacture of biotherapeutic protein products can be an arduous process relying on the…”
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IgG light chain-independent secretion of heavy chain dimers: consequence for therapeutic antibody production and design
Published in Biochemical journal (15-09-2017)“…Rodent monoclonal antibodies with specificity towards important biological targets are developed for therapeutic use by a process of humanisation. This process…”
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A comparative analysis of recombinant Fab and full‐length antibody production in Chinese hamster ovary cells
Published in Biotechnology and bioengineering (01-12-2021)“…Monoclonal antibodies are the leading class of biopharmaceuticals in terms of numbers approved for therapeutic purposes. Antigen‐binding fragments (Fab) are…”
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Engineering an Improved IgG4 Molecule with Reduced Disulfide Bond Heterogeneity and Increased Fab Domain Thermal Stability
Published in The Journal of biological chemistry (13-07-2012)“…The integrity of antibody structure, stability, and biophysical characterization are becoming increasingly important as antibodies receive increasing scrutiny…”
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The rapid generation of recombinant functional monoclonal antibodies from individual, antigen-specific bone marrow-derived plasma cells isolated using a novel fluorescence-based method
Published in mAbs (01-01-2014)“…Single B cell technologies, which avoid traditional hybridoma fusion and combinatorial display, provide a means to interrogate the naturally-selected antibody…”
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Elevated Left Ventricular Outflow Tract Velocities on Exercise Stress Echocardiography May Be a Normal Physiologic Response in Healthy Youth
Published in Journal of the American Society of Echocardiography (01-12-2013)“…Background Children with heart disease are at risk for sudden death during exercise, yet decisions regarding sports participation are often based on resting…”
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A comparison of the thermal properties of 2- and 3-fluted drills and the effects on bone cell viability and screw pull-out strength in an ovine model
Published in Clinical biomechanics (Bristol) (01-07-2010)“…Abstract Background Drilling of bone is associated with an increase in temperature of the surrounding bone which may result in osteonecrosis. Methods In this…”
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Working with Military Families Through Deployment and Beyond
Published in Clinical social work journal (01-03-2011)“…Military families experience considerable stress, periods of long separation, and changes to the family system due to family members planning to enter a war…”
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Effects of Low-Intensity Pulsed Ultrasound on Tendon–Bone Healing in an Intra-articular Sheep Knee Model
Published in Arthroscopy (01-02-2007)“…Purpose: This study reports the mechanical and histologic properties of intra-articular tendon–bone healing with the application of low-intensity pulsed…”
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Electrocardiographic Findings in Genotype-Positive and Non-sarcomeric Children with Definite Hypertrophic Cardiomyopathy and Subclinical Variant Carriers
Published in Pediatric cardiology (01-12-2024)“…In children with hypertrophic cardiomyopathy (HCM), the genotype–phenotype association of abnormal electrocardiographic (ECG) features in the backdrop of gene…”
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When Programs Collide: A Panel Report on the Competing Interests of Analytics and Security
Published in Communications of the Association for Information Systems (01-01-2020)“…The increasing demand for business analytics and cybersecurity professionals provides an exciting job outlook for graduates of information systems programs…”
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Presentation of JCSW Issue 2011/1
Published in Journal of comparative social work (01-04-2011)Get full text
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TNF-α converting enzyme (TACE) is inhibited by TIMP-3
Published in FEBS letters (11-09-1998)“…TNF-α converting enzyme (TACE; ADAM-17) is a membrane-bound disintegrin metalloproteinase that processes the membrane-associated cytokine proTNF-α to a soluble…”
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Anomalous Aortic Origin of a Coronary Artery With an Interarterial Course
Published in Journal of the American College of Cardiology (27-05-2008)“…Anomalous Aortic Origin of a Coronary Artery With an Interarterial Course: Should Family Screening Be Routine? Julie A. Brothers, Paul Stephens, J. William…”
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High Resolution NMR-based Model for the Structure of a scFv-IL-1β Complex: POTENTIAL FOR NMR AS A KEY TOOL IN THERAPEUTIC ANTIBODY DESIGN AND DEVELOPMENT
Published in The Journal of biological chemistry (2009)“…Monoclonal antibodies have recently started to deliver on their promise as highly specific and active drugs; however, a more effective, knowledge-based…”
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Operationalizing Heedful Interrelating: How Attending, Responding, and Feeling Comprise Coordinating and Predict Performance in Self-Managing Teams
Published in Frontiers in psychology (18-03-2016)“…Team coordination implies a system of individual behavioral contributions occurring within a network of interpersonal relationships to achieve a collective…”
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Reduced Culture Temperature Differentially Affects Expression and Biophysical Properties of Monoclonal Antibody Variants
Published in Antibodies (Basel) (29-08-2014)“…Reduced culture temperature is an increasingly popular practice to improve recombinant protein yields in CHO cells. Recent studies have attributed the…”
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Postoperative Obstruction of the Pulmonary Veins in Mixed Total Anomalous Pulmonary Venous Connection
Published in Pediatric cardiology (01-10-2018)“…Total anomalous pulmonary venous connection (TAPVC) is a rare form of congenital heart disease in which the pulmonary veins drain by various pathways to the…”
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