Search Results - "Stephens, Melissa T."
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High-quality genetic mapping with ddRADseq in the non-model tree Quercus rubra
Published in BMC genomics (30-05-2017)“…Restriction site associated DNA sequencing (RADseq) has the potential to be a broadly applicable, low-cost approach for high-quality genetic linkage mapping in…”
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An SNP-based second-generation genetic map of Daphnia magna and its application to QTL analysis of phenotypic traits
Published in BMC genomics (27-11-2014)“…Although Daphnia is increasingly recognized as a model for ecological genomics and biomedical research, there is, as of yet, no high-resolution genetic map for…”
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Quality control recommendations for RNASeq using FFPE samples based on pre-sequencing lab metrics and post-sequencing bioinformatics metrics
Published in BMC medical genomics (16-09-2022)“…Formalin-fixed, paraffin-embedded (FFPE) tissues have many advantages for identification of risk biomarkers, including wide availability and potential for…”
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Inversion Genotyping in the Anopheles gambiae Complex Using High-Throughput Array and Sequencing Platforms
Published in G3 : genes - genomes - genetics (01-09-2020)“…Chromosomal inversion polymorphisms have special importance in the complex of malaria vector mosquitoes, due to their role in local adaptation and range…”
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High-Throughput Genotyping of Common Chromosomal Inversions in the Afrotropical Malaria Mosquito Anopheles Funestus
Published in Insects (Basel, Switzerland) (13-10-2020)“…Polymorphic chromosomal inversions have been implicated in local adaptation. In anopheline mosquitoes, inversions also contribute to epidemiologically relevant…”
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ColoType: a forty gene signature for consensus molecular subtyping of colorectal cancer tumors using whole-genome assay or targeted RNA-sequencing
Published in Scientific reports (21-07-2020)“…Colorectal cancer (CRC) tumors can be partitioned into four biologically distinct consensus molecular subtypes (CMS1-4) using gene expression. Evidence is…”
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Genome-wide profiling of 24 hr diel rhythmicity in the water flea, Daphnia pulex: network analysis reveals rhythmic gene expression and enhances functional gene annotation
Published in BMC genomics (18-08-2016)“…Marine and freshwater zooplankton exhibit daily rhythmic patterns of behavior and physiology which may be regulated directly by the light:dark (LD) cycle…”
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Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials
Published in Journal of medicinal chemistry (11-04-2019)“…Malaria remains one of the deadliest diseases in the world today. Novel chemoprophylactic and chemotherapeutic antimalarials are needed to support the renewed…”
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Evaluating cell type deconvolution in FFPE breast tissue: application to benign breast disease
Published in NAR genomics and bioinformatics (06-08-2024)“…Abstract Transcriptome profiling using RNA sequencing (RNA-seq) of bulk formalin-fixed paraffin-embedded (FFPE) tissue blocks is a standard method in…”
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Genome-wide polymorphisms and development of a microarray platform to detect genetic variations in Plasmodium yoelii
Published in Molecular and biochemical parasitology (01-03-2014)“…Genome-wide genotyping single nucleotide polymorphism (SNP) and detection of genetic crossovers in Plasmodum yoelii using a microarray. •Genome sequencing of…”
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