Search Results - "Stephens, Carson R"

Prostate Cancer-Associated Kallikrein-Related Peptidase 4 Activates Matrix Metalloproteinase‑1 and Thrombospondin‑1 by Fuhrman-Luck, Ruth A, Stansfield, Scott H, Stephens, Carson R, Loessner, Daniela, Clements, Judith A

“…Prostate cancer metastasis to bone is terminal; thus, novel therapies are required to prevent end-stage disease. Kallikrein-related peptidase 4 (KLK4) is a…”
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Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells by Lawrence, Mitchell G., Margaryan, Naira V., Loessner, Daniela, Collins, Angus, Kerr, Kris M., Turner, Megan, Seftor, Elisabeth A., Stephens, Carson R., Lai, John, Postovit, Lynne-Marie, Clements, Judith A., Hendrix, Mary J.C.

“…BACKGROUND Nodal is a member of the transforming growth factor β (TGFβ) superfamily that directs embryonic patterning and promotes the plasticity and…”
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Kallikrein‐related peptidase 4 induces cancer‐associated fibroblast features in prostate‐derived stromal cells by Kryza, Thomas, Silva, Lakmali M., Bock, Nathalie, Fuhrman‐Luck, Ruth A., Stephens, Carson R., Gao, Jin, Samaratunga, Hema, Lawrence, Mitchell G., Hooper, John D., Dong, Ying, Risbridger, Gail P., Clements, Judith A.

“…The reciprocal communication between cancer cells and their microenvironment is critical in cancer progression. Although involvement of cancer‐associated…”
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In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B by Reid, Janet C, Bennett, Nigel C, Stephens, Carson R, Carroll, Melanie L, Magdolen, Viktor, Clements, Judith A, Hooper, John D

“…Kallikrein-related peptidase (KLK) 14 is a serine protease linked to several pathologies including prostate cancer. We show that KLK14 has biphasic effects in…”
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Long Terminal Repeats Act as Androgen-Responsive Enhancers for the PSA-Kallikrein Locus by Lawrence, Mitchell G, Stephens, Carson R, Need, Eleanor F, Lai, John, Buchanan, Grant, Clements, Judith A

“…The androgen receptor (AR) signaling pathway is a common therapeutic target for prostate cancer, because it is critical for the survival of both…”
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EphB4 localises to the nucleus of prostate cancer cells by Mertens-Walker, Inga, Lisle, Jessica E., Nyberg, William A., Stephens, Carson R., Burke, Leslie, Rutkowski, Raphael, Herington, Adrian C., Stephenson, Sally-Anne

“…The EphB4 receptor tyrosine kinase is over-expressed in a variety of different epithelial cancers including prostate where it has been shown to be involved in…”
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Substrate-Guided Design of a Potent and Selective Kallikrein-Related Peptidase Inhibitor for Kallikrein 4 by Swedberg, Joakim E., Nigon, Laura V., Reid, Janet C., de Veer, Simon J., Walpole, Carina M., Stephens, Carson R., Walsh, Terry P., Takayama, Thomas K., Hooper, John D., Clements, Judith A., Buckle, Ashley M., Harris, Jonathan M.

“…Human kallikrein-related peptidase 4 (KLK4/prostase), a trypsin-like serine protease, is a potential target for prostate cancer treatment because of its…”
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Reactivation of Embryonic Nodal Signaling Is Associated WithTumor Progression and Promotes the Growth of Prostate Cancer Cells by LAWRENCE, Mitchell G, MARGARYAN, Naira V, POSTOVIT, Lynne-Marie, CLEMENTS, Judith A, HENDRIX, Mary J. C, LOESSNER, Daniela, COLLINS, Angus, KERR, Kris M, TURNER, Megan, SEFTOR, Elisabeth A, STEPHENS, Carson R, LAI, John, BIORESOURCE, Apc

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