Search Results - "Stephen Kegg"

Impact on life expectancy of HIV-1 positive individuals of CD4+ cell count and viral load response to antiretroviral therapy by MAY, Margaret T, GOMPELS, Mark, CHADWICK, David, MARTIN, Fabiola, HILL, Teresa, WALSH, John, POST, Frank, FISHER, Martin, AINSWORTH, Jonathan, JOSE, Sophie, LEEN, Clifford, NELSON, Mark, DELPECH, Valerie, ANDERSON, Jane, SABIN, Caroline, PORTER, Kholoud, ORKIN, Chloe, KEGG, Stephen, HAY, Phillip, JOHNSON, Margaret, PALFREEMAN, Adrian, GILSON, Richard

“…The objective of this study is to estimate life expectancies of HIV-positive patients conditional on response to antiretroviral therapy (ART). Patients aged…”
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Hepatitis B, hepatitis C and mortality among HIV-positive individuals by Thornton, Alicia C, Jose, Sophie, Bhagani, Sanjay, Chadwick, David, Dunn, David, Gilson, Richard, Main, Janice, Nelson, Mark, Rodger, Alison, Taylor, Chris, Youssef, Elaney, Leen, Clifford, Gompels, Mark, Kegg, Stephen, Schwenk, Achim, Sabin, Caroline

“…OBJECTIVES:To compare rates of all-cause, liver-related and AIDS-related mortality among individuals who are HIV mono-infected with those co-infected with HIV…”
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Safety and Immunogenicity of an Adjuvanted Herpes Zoster Subunit Candidate Vaccine in HIV-Infected Adults: A Phase 1/2a Randomized, Placebo-Controlled Study by Berkowitz, Elchonon M., Moyle, Graeme, Stellbrink, Hans-Jürgen, Schürmann, Dirk, Kegg, Stephen, Stoll, Matthias, Idrissi, Mohamed El, Oostvogels, Lidia, Heineman, Thomas C.

“…Background. Human immunodeficiency virus (HIV)-infected individuals are at increased risk of herpes zoster (HZ), even in the antiretroviral therapy (ART) era…”
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Who gets single tablet regimens (STR), and why? by Tarrier, Laura, Kegg, Stephen

“…Introduction The BHIVA guidelines now feature three single tablet regimens (STRs) as recommended treatments for HIV‐positive people new to therapy [1]. They…”
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HIV outcomes during the COVID‐19 pandemic in people of Black ethnicities living with HIV in England by Ottaway, Zoe, Campbell, Lucy, Fox, Julie, Burns, Fiona, Hamzah, Lisa, Kegg, Stephen, Rosenvinge, Melanie, Schoeman, Sarah, Price, David, Jones, Rachael, Miller, Robert F., Tariq, Shema, Post, Frank A.

“…Objectives To describe HIV care outcomes in people of Black ethnicities living in England during the severe acute respiratory syndrome coronavirus 2…”
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Cardiovascular disease risk in people of African ancestry with HIV in the United Kingdom by Ko, Stephanie, Dominguez-Dominguez, Lourdes, Ottaway, Zoe, Campbell, Lucy, Fox, Julie, Burns, Fiona, Hamzah, Lisa, Ustianowski, Andrew, Clarke, Amanda, Kegg, Stephen, Schoeman, Sarah, Jones, Rachael, Pett, Sarah L, Hudson, Jonathan, Post, Frank A

“…Our objective was to describe the prevalence of cardiovascular disease (CVD) risk factors in people of African ancestry with HIV in the UK. We conducted a…”
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Clinical characteristics and outcomes of HIV-associated immune complex kidney disease by Booth, John W, Hamzah, Lisa, Jose, Sophie, Horsfield, Catherine, O'Donnell, Patrick, McAdoo, Stephen, Kumar, Emil A, Turner-Stokes, Tabitha, Khatib, Nadia, Das, Partha, Naftalin, Claire, Mackie, Nicola, Kingdon, Ed, Williams, Debbie, Hendry, Bruce M, Sabin, Caroline, Jones, Rachael, Levy, Jeremy, Hilton, Rachel, Connolly, John, Post, Frank A

“…The pathogenesis and natural history of HIV-associated immune complex kidney disease (HIVICK) is not well understood. Key questions remain unanswered,…”
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Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 48-week results of a randomised, double-blind, phase 3, non-inferiority trial by Squires, Kathleen, Cahn, Pedro, Lombaard, Johan, DeJesus, Edwin, Lai, Ming-Tain, Rodgers, Anthony, Kumar, Sushma, Sklar, Peter, Nguyen, Bach-Yen, Hanna, George J, Hwang, Carey, Martins, Marcelo, Bloch, Mark Theo, Baker, David Alfred, Roth, Norman, Moore, Richard James, McMahon, James, Rieger, Armin, Zoufaly, Alexander, Zangerle, Robert, Smaill, Fiona, Rachlis, Anita, Perez, Carlos, Campos Barker, Maria Isabel E., Wolff Reyes, Marcelo, Laursen, Alex Lund, Molina, Jean-Michel, Yazdanpanah, Yazdan, Cotte, Laurent, Raffi, Francois, Morlat, Philippe, Girard, Pierre-Marie, Katlama, Christine, Rockstroh, Juergen K., Arasteh, Keikawus, Stoehr, Albrecht, Stellbrink, Hans-Juergen, Stoll, Matthias, Schuermann, Dirk, Faetkenheuer, Gerd, Bogner, Johannes, Gori, Andrea, Coltan, Gabriel, Constandis, Felicia, Erscoiu, Simona Manuela, Pokrovsky, Vadim Valentinovich, Shuldyakov, Andrey Anatolyevich, Ryamova, Elena Pavlovna, Kulagin, Valeriy Viktorovich, Tsybakova, Olga Aleksandrovna, Orlova-Morozova, Elena, Shimonova, Tatyana Evgenyevna, Kozyrev, Oleg Anatolyevich, Orrell, Catherine, Lombaard, Johannes Jurgens, Botes, Margaretha Elizabeth, Portilla, Joaquin, Gatell, Josep Maria, Perez, Maria Jesus, Arribas, Jose Ramon, Negredo, Eugenia, Podzamczer, Daniel, Troya, Jesus, De los Santos, Ignacio, Berenguer, Juan, Williams, Ian G., Johnson, Margaret A., Schembri, Gabriel, Gompels, Mark, Fox, Julie Meriel, Taylor, Steven John, Kegg, Stephen, Hagins, Debbie P., Osiyemi, Olayemi O., Prelutsky, David James, Ramgopal, Moti N., Dretler, Robin, DeJesus, Edwin, Sloan, Louis, Lewis, Stanley T., Clay, Patrick G., Bellos, Nicholaos C., Montero, Jose, Creticos, Catherine, Shamblaw, David, Valdes, Martin, Felizarta, Franco Antonio, Slim, Jihad, Lalezari, Jacob Paul, Ruane, Peter Jerome, Cade, Jerry L., Campo, Rafael E., Blick, Gary, Mayer, Cynthia, Daar, Eric, Kumar, Princy N., Swindells, Susan, Castro, Jose Guillermo, Santiago, Lizette, Santana-Bagur, Jorge L.

“…Doravirine is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) with a pharmacokinetic profile supporting once-daily dosing, and potent in-vitro…”
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Long-term safety and efficacy of emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV-1 pre-exposure prophylaxis: week 96 results from a randomised, double-blind, placebo-controlled, phase 3 trial by Ogbuagu, Onyema, Ruane, Peter J, Podzamczer, Daniel, Salazar, Laura C, Asmuth, David M, Wohl, David, Gilson, Richard, Shao, Yongwu, Cox, Stephanie, Kintu, Alexander, Carter, Christoph, Baeten, Jared M, Brainard, Diana M, Whitlock, Gary, Brunetta, Jason M, Spinner, Christoph D, Antinori, Andrea, Apea, Vanessa, Avery, Ann, Benson, Paul, Bergin, Colm, Berhe, Mezgebe, Brar, Indira, Brinson, Cynthia, Brunetta, Jason, Burack, Jeffrey, Campbell, Thomas, Cespedes, Michelle, Clarke, Amanda, Coleman, Megan, Coll, Josep, Crespo Casal, Manuel, Creticos, Catherine, Crofoot, Gordon, Cruickshank, Frederick, Cua, Eric, Daar, Eric, de Wet, Joseph, DeJesus, Edwin, Del Romero Guerrero, Jorge, Dinges, William, Donovan, Taylor, Flamm, Jason, Gallant, Joel, Gerstoft, Jan, Gilson, Richard, Gladstein, Jay, Grant, Robert, Halperin, Jason, Hardy, W. David, Hare, Charles, Hassler, Shawn, Hengel, Richard, Henry, William, Hodge, Theo, Iandiorio, Michelle, Jessen, Heiko, Kegg, Stephen, Knecht, Gabriele, Krznaric, Ivanka, Larsen, Olav Ditlevsen, Lazzarin, Adriano, Leen, Clifford, Lucasti, Christopher, Mallon, Patrick, Mannheimer, Sharon, Markowitz, Martin, Martorell, Claudia, Mayer, Kenneth, Mills, Anthony, Molina, Jean-Michel, Morris, Sheldon, Mounzer, Karam, Nwokolo, Nneka, Osiyemi, Olayemi, Petroll, Andrew, Philibert, Patrick, Phoenix, John, Pialoux, Gilles, Podzamczer, Daniel, Post, Frank, Rashbaum, Bruce, Reeves, Iain, Richmond, Gary, Salazar, Laura, Scarsella, Anthony, Schembri, Gabriel, Scott, Mia, Sinclair, Gary, Sobieszczyk, Magdalena, Spinner, Christoph, Stephens, Jeffrey, Szabo, Jason, Tremblay, Cecile, Trottier, Benoit, Voskuhl, Gene, Wohl, David, Workowski, Kimberly, Yawetz, Sigal, Young, Benjamin

“…In DISCOVER, a multinational, randomised controlled trial, emtricitabine and tenofovir alafenamide compared with emtricitabine and tenofovir disoproxil…”
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Incomplete Reversibility of Estimated Glomerular Filtration Rate Decline Following Tenofovir Disoproxil Fumarate Exposure by Jose, Sophie, Hamzah, Lisa, Campbell, Lucy J., Hill, Teresa, Fisher, Martin, Leen, Clifford, Gilson, Richard, Walsh, John, Nelson, Mark, Hay, Phillip, Johnson, Margaret, Chadwick, David, Nitsch, Dorothea, Jones, Rachael, Sabin, Caroline A., Post, Frank A.

“…Background. Tenofovir disoproxil fumarate (TDF) has been linked to renal impairment, but the extent to which this impairment is reversible is unclear. We aimed…”
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Clinical epidemiology of COVID‐19 in people of black ethnicity living with HIV in the UK by Ottaway, Zoe, Campbell, Lucy, Cechin, Laura R., Patel, Nisha, Fox, Julie, Rosenvinge, Melanie, Schoeman, Sarah, Price, David, Jones, Rachael, Clarke, Amanda, Maan, Irfaan, Ustianowski, Andrew, Onyango, Denis, Tariq, Shema, Miller, Robert F., Post, Frank A., Clarke, Amanda, Knott, Alyson, Trevitt, Vittorio, Schoolmeesters, Alex, Ghazali, Shoreh, Fox, Julie, Waters, Anele, Racz, Mariusz, Arbis, Kathy, Post, Frank, Ottaway, Zoe, Santana‐Suarez, Beatriz, McQueen, Leigh, Campbell, Lucy, Barbini, Bee, Wandolo, Emily, Hung, Rachel, Hanbury, Luella, Barber, Sarah, Taylor, Chris, Poulton, Mary, Middleditch, Holly, McDonald, Candice, Kolodin, Vladimir, Cechin, Laura, Mulka, Larissa, John, Amy, Hawkins, Sally, Bainbridge, Katherine, Barker, Julie, Childs, Kate, Shorrock, Lisa, El Bouzidi, Kate, Oliveira, Amelia, Ratnappuli, Ayoma, Flanagan, Kate, Mody, Nisha, Brady, Michael, Quinn, Killian, Hamlyn, Elizabeth, Sandhu, Gurjinder, Sullivan, Verity, Fitzgerald, Naomi, Schoeman, Sarah, Lamont, Gary, Calder‐Smith, Natasha, Mazeika, Tadas, Chana, Kiran, Ustianowski, Andrew, Lindergard, Gabriella, Flaherty, Jan, George, Valerie, Kadiu, Denise, Hendy, Alice, Kuriakose, Kevin, Pett, Sarah, Qamar, Mah Jabeen, Sosa, Jose Paredes, Tetorou, Konstantina, Beynon, Michelle, Yinka‐Ogunleye, Adesola, Gopalakrishnan, Gosala, Maan, Irfaan, Mullender, Claire, Price, David Ashley, Patel, Bijal, McVittie, Ian, Kegg, Stephen, Harrington, Rosa, Cunningham, Kirsty, Lewis, Mandy, Edwards, Jonathan, Fernandez, Tom, Egeh, Qayo, Spears, Katie, Hamzah, Lisa, Cosgrove, Catherine, Laurence, Hannah, Rahman, Ameen, Toler, Katie, Rosenvinge, Melanie, Adade, Claudia, Campbell, Shelley, Onyango, Denis

“…Objectives To describe the clinical epidemiology of COVID‐19 in people of black ethnicity living with HIV in the UK. Methods We investigated the incidence and…”
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Chronic Kidney Disease Risk in African and Caribbean Populations With HIV by Jose, Sophie, Hamzah, Lisa, Jones, Rachael, Williams, Debbie, Winston, Alan, Burns, Fiona, Phillips, Andrew N, Sabin, Caroline A, Post, Frank A

“…We conducted an observational cohort study of end-stage kidney disease (ESKD) in >7000 African and Caribbean people with HIV in the UK. Using Poisson…”
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Bone mineral density, kidney function and participant‐reported outcome measures in women who switch from tenofovir disoproxil emtricitabine and a nonnucleoside reverse transcriptase inhibitor to abacavir, lamivudine and dolutegravir by Campbell, Lucy, Ibrahim, Fowzia, Barbini, Birgit, Samarawickrama, Amanda, Orkin, Chloe, Fox, Julie, Waters, Laura, Gilleece, Yvonne, Tariq, Shema, Post, Frank A., Post, Frank, Adegbaju, Oluwayomi, Hamzah, Lisa, Bhagwandin, Priya, Canoso, Ana, Kegg, Stephen, Moussaoui, Tarik, Lwanga, Julianne, Sharp, Alice, Aminata, Mohammed, John‐Baptiste, Ange, Hamzah, Lisa, Prime, Katia, Okolo, Olanike, Waters, Anele, Cartier, Andrea, Johnson, Margaret, Nightingale, Alice, Edwards, Jonathan, Fernandez, Thomas, Hemat, Nargis, Ainsworth, Jonathan, Vincent, Rachel, Barbour, Lisa, Kirk, Sarah, Adams, Tanya, Knott, Alyson

“…Objectives Tenofovir disoproxil fumarate (TDF) is associated with reduced bone mineral density (BMD). The aim of the study was to evaluate changes in BMD in…”
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A continuum of HIV care describing mortality and loss to follow-up: a longitudinal cohort study by Jose, Sophie, Delpech, Valerie, Howarth, Alison, Burns, Fiona, Hill, Teresa, Porter, Kholoud, Sabin, Caroline A, Ainsworth, Jonathan, Allan, Sris, Anderson, Jane, Babiker, Abdel, Chadwick, David R, Churchill, Duncan, Dunn, David, Gilson, Richard, Gompels, Mark, Hay, Phillip, Johnson, Margaret, Kegg, Stephen, Leen, Clifford, Martin, Fabiola, Mital, Dushyant, Nelson, Mark, Orkin, Chloe, Palfreeman, Adrian, Phillips, Andrew, Pillay, Deenan, Post, Frank, Pritchard, Jillian, Scwenk, Achim, Tariq, Anjum, Trevelion, Roy, Ustianowski, Andy, Walsh, John

“…The cross-sectional HIV care continuum is widely used to assess the success of HIV care programmes among populations of people with HIV and the potential for…”
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Switching to dolutegravir plus rilpivirine versus maintaining current antiretroviral therapy regimen in virologically suppressed people with HIV-1 and the Lys103Asn (K103N) mutation: 48-week results from a randomised, open-label pilot clinical trial by Moyle, Graeme, Assoumou, Lambert, de Castro, Nathalie, Post, Frank A, Curran, Adrian, Rusconi, Stefano, De Wit, Stephane, Stephan, Christoph, Raffi, François, Johnson, Margaret, Masia, Mar, Vera, Jaime, Jones, Bryn, Grove, Richard, Fletcher, Carl, Duffy, Annie, Morris, Kellie, Pozniak, Anton, Moyle, Graeme, de Castro, Nathalie, Post, Frank, Curran, Adrian, Rusconi, Stefano, De Wit, Stephane, Stephan, Christoph, Raffi, François, Johnson, Margaret, Masia, Mar, Vera, Jaime, Winston, Alan, Kegg, Stephen, Waters, Laura, Orkin, Chole, Ustianowski, Andrew, Reeves, Iain, Leen, Clifford, Perry, Meghan, Portilla, Joaquin, Blanco, Jose Luis, Montejaro, Rocio, Domingo, Pere, Molina, Jean Michel, Katlama, Christine, Morlat, Philippe, Kenyon, Christopher, Puoti, Massimo, Rizzardini, Giuliano, Castagna, Antonella, Castelli, Francesco, Giacomelli, Andrea, Rockstroh, Jürgen, Esser, Stefan, Hoffmann, Christian, Mallon, Patrick

“…The combination of dolutegravir plus rilpivirine has been studied in people with virologically suppressed HIV with no previous history of treatment failure or…”
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HIV-1 drug resistance mutations emerging on darunavir therapy in PI-naive and -experienced patients in the UK by El Bouzidi, Kate, White, Ellen, Mbisa, Jean L, Sabin, Caroline A, Phillips, Andrew N, Mackie, Nicola, Pozniak, Anton L, Tostevin, Anna, Pillay, Deenan, Dunn, David T

“…Darunavir is considered to have a high genetic barrier to resistance. Most darunavir-associated drug resistance mutations (DRMs) have been identified through…”
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Virological outcomes of boosted protease inhibitor-based first-line ART in subjects harbouring thymidine analogue-associated mutations as the sole form of transmitted drug resistance by Geretti, Anna Maria, White, Ellen, Orkin, Chloe, Tostevin, Anna, Tilston, Peter, Chadwick, David, Leen, Clifford, Sabin, Caroline, Dunn, David T

“…Abstract Objectives In subjects with transmitted thymidine analogue mutations (TAMs), boosted PIs (PI/b) are often chosen to overcome possible resistance to…”
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The contribution of viral genotype to plasma viral set-point in HIV infection by Hodcroft, Emma, Hadfield, Jarrod D, Fearnhill, Esther, Phillips, Andrew, Dunn, David, O'Shea, Siobhan, Pillay, Deenan, Leigh Brown, Andrew J

“…Disease progression in HIV-infected individuals varies greatly, and while the environmental and host factors influencing this variation have been widely…”
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An association between K65R and HIV-1 subtype C viruses in patients treated with multiple NRTIs by Smit, Erasmus, White, Ellen, Clark, Duncan, Churchill, Duncan, Zhang, Hongyi, Collins, Simon, Pillay, Deenan, Sabin, Caroline, Nelson, Mark, Winston, Alan, Jose, Sophie, Tostevin, Anna, Dunn, David T

“…HIV-1 subtype C might have a greater propensity to develop K65R mutations in patients with virological failure compared with other subtypes. However, the…”
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Predicting virological decay in patients starting combination antiretroviral therapy by Hughes, Rachael

“…OBJECTIVE:Model trajectories of viral load measurements from time of starting combination antiretroviral therapy (cART), and use the model to predict whether…”
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