Search Results - "Stephen D. Fox"

Acetylation of Cytidine in mRNA Promotes Translation Efficiency by Arango, Daniel, Sturgill, David, Alhusaini, Najwa, Dillman, Allissa A., Sweet, Thomas J., Hanson, Gavin, Hosogane, Masaki, Sinclair, Wilson R., Nanan, Kyster K., Mandler, Mariana D., Fox, Stephen D., Zengeya, Thomas T., Andresson, Thorkell, Meier, Jordan L., Coller, Jeffery, Oberdoerffer, Shalini

“…Generation of the “epitranscriptome” through post-transcriptional ribonucleoside modification embeds a layer of regulatory complexity into RNA structure and…”
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Metformin prevents tobacco carcinogen--induced lung tumorigenesis by Memmott, Regan M, Mercado, Jose R, Maier, Colleen R, Kawabata, Shigeru, Fox, Stephen D, Dennis, Phillip A

“…Activation of the mammalian target of rapamycin (mTOR) pathway is an important and early event in tobacco carcinogen-induced lung tumorigenesis, and therapies…”
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SSSPTA is essential for serine palmitoyltransferase function during development and hematopoiesis by Parthibane, Velayoudame, Lin, Jing, Acharya, Diwash, Abimannan, Thiruvaimozhi, Srideshikan, Sargur Madabushi, Klarmann, Kimberly, Yang, Acong, Soheilian, Ferri, Nagashima, Kunio, Fox, Stephen D., Andresson, Thorkell, Tessarollo, Lino, Keller, Jonathan R., Acharya, Usha, Acharya, Jairaj K.

“…Serine palmitoyltransferase complex (SPT) mediates the first and rate-limiting step in the de novo sphingolipid biosynthetic pathway. The larger subunits…”
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Glutamine synthetase is necessary for sarcoma adaptation to glutamine deprivation and tumor growth by Issaq, Sameer H., Mendoza, Arnulfo, Fox, Stephen D., Helman, Lee J.

“…Despite a growing body of knowledge about the genomic landscape and molecular pathogenesis of sarcomas, translation of basic discoveries into targeted…”
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Rapamycin Protects Mice from Staphylococcal Enterotoxin B-Induced Toxic Shock and Blocks Cytokine Release In Vitro and In Vivo by KRAKAUER, Teresa, BUCKLEY, Marilyn, ISSAQ, Haleem J, FOX, Stephen D

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Serial Free Bisphenol A and Bisphenol A Glucuronide Concentrations in Neonates by Nachman, Rebecca M., PhD, MPH, Fox, Stephen D., BS, Golden, W. Christopher, MD, Sibinga, Erica, MD, MHS, Groopman, John D., PhD, Lees, Peter S.J., PhD

“…Objective To determine the balance of metabolism of free bisphenol A (BPA) to the inactive conjugate, BPA glucuronide (BPAG), in neonates. Study design Free…”
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Urinary Free Bisphenol A and Bisphenol A-Glucuronide Concentrations in Newborns by Nachman, Rebecca M., MPH, Fox, Stephen D., BS, Golden, W. Christopher, MD, Sibinga, Erica, MD, Veenstra, Timothy D., PhD, Groopman, John D., PhD, Lees, Peter S.J., PhD

“…Infants are exposed to the endocrine disruptor bisphenol A (BPA) through breast milk and baby formula. Detoxication by conjugation of BPA may be limited in…”
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Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation by HODGE, David R, BENJAMIN PENG, CHERRY, James C, HURT, Elaine M, FOX, Stephen D, KELLEY, James A, MUNROE, David J, FARRAR, William L

“…A strong association exists between states of chronic inflammation and cancer, and it is believed that mediators of inflammation may be responsible for this…”
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Global proteomics and metabolomics in cancer biomarker discovery by Issaq, Haleem J, Fox, Stephen D, Chan, King C, Veenstra, Timothy D

“…Chromatography and electrophoresis have been used for the last half‐century to separate small and large molecules. Advances in MS instrumentation and…”
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Identification of a Highly Effective Rapamycin Schedule that Markedly Reduces the Size, Multiplicity, and Phenotypic Progression of Tobacco Carcinogen–Induced Murine Lung Tumors by GRANVILLE, Courtney A, WARFEL, Noel, TSURUTANI, Junji, HOLLANDER, M. Christine, ROBERTSON, Matthew, FOX, Stephen D, VEENSTRA, Timothy D, ISSAQ, Haleem J, LINNOILA, R. Llona, DENNIS, Phillip A

“…Purpose: Human and murine preneoplastic lung lesions induced by tobacco exposure are characterized by increased activation of the Akt/mammalian target of…”
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Quantitation of free and total bisphenol A in human urine using liquid chromatography-tandem mass spectrometry by Fox, Stephen D., Falk, Roni T., Veenstra, Timothy D., Issaq, Haleem J.

“…Bisphenol A (BPA) is employed in the synthesis of polycarbonate plastics and epoxy resins and is widely used in consumer products including as a coating for…”
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Sptlc1 is essential for myeloid differentiation and hematopoietic homeostasis by Parthibane, Velayoudame, Acharya, Diwash, Srideshikan, Sargur Madabushi, Lin, Jing, Myerscough, Dru G., Abimannan, Thiruvaimozhi, Vijaykrishna, Nagampalli, Blankenberg, Daniel, Bondada, Lavanya, Klarmann, Kimberly D., Fox, Stephen D., Andresson, Thorkell, Tessarollo, Lino, Acharya, Usha, Keller, Jonathan R., Acharya, Jairaj K.

“…Serine palmitoyltransferase (SPT) long-chain base subunit 1 (SPTLC1) is 1 of the 2 main catalytic subunits of the SPT complex, which catalyzes the first and…”
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A Chemical Signature for Cytidine Acetylation in RNA by Thomas, Justin M, Briney, Chloe A, Nance, Kellie D, Lopez, Jeffrey E, Thorpe, Abigail L, Fox, Stephen D, Bortolin-Cavaille, Marie-Line, Sas-Chen, Aldema, Arango, Daniel, Oberdoerffer, Shalini, Cavaille, Jerome, Andresson, Thorkell, Meier, Jordan L

“…N4-acetylcytidine (ac4C) is a highly conserved modified RNA nucleobase whose formation is catalyzed by the disease-associated N-acetyltransferase 10 (NAT10)…”
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Protonation-Dependent Sequencing of 5‑Formylcytidine in RNA by Link, Courtney N, Thalalla Gamage, Supuni, Gallimore, Diamond, Kopajtich, Robert, Evans, Christine, Nance, Samantha, Fox, Stephen D, Andresson, Thorkell, Chari, Raj, Ivanic, Joseph, Prokisch, Holger, Meier, Jordan L

“…Chemical modification of cytidine in noncoding RNAs plays a key role in regulating translation and disease. However, the distribution and dynamics of many of…”
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Specific inhibition of an anticancer target, polo-like kinase 1, by allosterically dismantling its mechanism of substrate recognition by Park, Jung-Eun, Kirsch, Klara, Lee, Hobin, Oliva, Paola, Ahn, Jong Il, Ravishankar, Harsha, Zeng, Yan, Fox, Stephen D, Kirby, Samuel A, Badhwar, Pooja, Andresson, Thorkell, Jacobson, Kenneth A, Lee, Kyung S

“…Polo-like kinase 1 (Plk1) is considered an attractive target for anticancer therapy. Over the years, studies on the noncatalytic polo-box domain (PBD) of Plk1…”
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CD4 T Cell Survival after Intermittent Interleukin-2 Therapy Is Predictive of an Increase in the CD4 T Cell Count of HIV-Infected Patients by Read, Sarah W., Lempicki, Richard A., Di Mascio, Michele, Srinivasula, Sharat, Burke, Rosanne, Sachau, William, Bosche, Marjorie, Adelsberger, Joseph W., Sereti, Irini, Davey, Richard T., Tavel, Jorge A., Huang, Chiung-Yu, Issaq, Haleem J., Fox, Stephen D., Lane, H. Clifford, Kovacs, Joseph A.

“…Administration of interleukin (IL)—2 to human immunodeficiency virus (HIV)—infected patients leads to significant increases in CD4 T cell counts. We previously…”
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Profiling Cytidine Acetylation with Specific Affinity and Reactivity by Sinclair, Wilson R, Arango, Daniel, Shrimp, Jonathan H, Zengeya, Thomas T, Thomas, Justin M, Montgomery, David C, Fox, Stephen D, Andresson, Thorkell, Oberdoerffer, Shalini, Meier, Jordan L

“…The human acetyltransferase NAT10 has recently been shown to catalyze formation of N4-acetylcytidine (ac4C), a minor nucleobase known to alter RNA structure…”
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A Systems Chemoproteomic Analysis of Acyl-CoA/Protein Interaction Networks by Levy, Michaella J, Montgomery, David C, Sardiu, Mihaela E, Montano, Jose L, Bergholtz, Sarah E, Nance, Kellie D, Thorpe, Abigail L, Fox, Stephen D, Lin, Qishan, Andresson, Thorkell, Florens, Laurence, Washburn, Michael P, Meier, Jordan L

“…Acyl-coenzyme A (CoA)/protein interactions are essential for life. Despite this importance, their global scope and selectivity remains undefined. Here, we…”
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Protonation‐Dependent Sequencing of 5‐Formylcytidine in RNA by Link, Courtney N., Thalalla Gamage, Supuni, Gallimore, Diamond A., Kopajtich, Robert, Evans, Christine N., Nance, Samantha R., Fox, Stephen D., Andresson, Thorkell, Chari, Raj, Ivanic, Joseph, Prokisch, Holger, Meier, Jordan L.

“…Chemical modification of cytidine in non‐coding RNAs plays a key role in regulating translation and disease. However, the distribution and dynamics of many of…”
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Urinary bisphenol A-glucuronide and postmenopausal breast cancer in Poland by Trabert, Britton, Falk, Roni T., Figueroa, Jonine D., Graubard, Barry I., Garcia-Closas, Montserrat, Lissowska, Jolanta, Peplonska, Beata, Fox, Stephen D., Brinton, Louise A.

“…Purpose: Concerns regarding a possible link between bisphenol A (BPA) and breast cancer have been mounting, but studies in human populations are lacking. We…”
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