Search Results - "Stephen B. Melville"

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  1. 1

    Expansion of the Clostridium perfringens toxin-based typing scheme by Rood, Julian I., Adams, Vicki, Lacey, Jake, Lyras, Dena, McClane, Bruce A., Melville, Stephen B., Moore, Robert J., Popoff, Michel R., Sarker, Mahfuzur R., Songer, J. Glenn, Uzal, Francisco A., Van Immerseel, Filip

    Published in Anaerobe (01-10-2018)
    “…Clostridium perfringens causes many different histotoxic and enterotoxic diseases in humans and animals as a result of its ability to produce potent protein…”
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  2. 2

    Construction and Characterization of a Lactose-Inducible Promoter System for Controlled Gene Expression in Clostridium perfringens by Hartman, Andrea H, Liu, Hualan, Melville, Stephen B

    Published in Applied and Environmental Microbiology (01-01-2011)
    “…Clostridium perfringens is a Gram-positive anaerobic pathogen which causes many diseases in humans and animals. While some genetic tools exist for working with…”
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  3. 3

    Cyclic Di-GMP Binding by an Assembly ATPase (PilB2) and Control of Type IV Pilin Polymerization in the Gram-Positive Pathogen Clostridium perfringens by Hendrick, William A, Orr, Mona W, Murray, Samantha R, Lee, Vincent T, Melville, Stephen B

    Published in Journal of bacteriology (15-05-2017)
    “…The Gram-positive pathogen possesses type IV pili (TFP), which are extracellular fibers that are polymerized from a pool of pilin monomers in the cytoplasmic…”
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  4. 4

    Type IV Pili and the CcpA Protein Are Needed for Maximal Biofilm Formation by the Gram-Positive Anaerobic Pathogen Clostridium perfringens by Varga, John J, Therit, Blair, Melville, Stephen B

    Published in Infection and Immunity (01-11-2008)
    “…The predominant organizational state of bacteria in nature is biofilms. Biofilms have been shown to increase bacterial resistance to a variety of stresses. We…”
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  5. 5

    Changes in the expression of genes encoding type IV pili-associated proteins are seen when Clostridium perfringens is grown in liquid or on surfaces by Soncini, Samantha R, Hartman, Andrea H, Gallagher, Tara M, Camper, Gary J, Jensen, Roderick V, Melville, Stephen B

    Published in BMC genomics (14-01-2020)
    “…Clostridium perfringens is a Gram-positive anaerobic pathogen that causes multiple diseases in humans and animals. C. perfringens lack flagella but have type…”
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  6. 6

    Sporulation and Enterotoxin (CPE) Synthesis Are Controlled by the Sporulation-Specific Sigma Factors SigE and SigK in Clostridium perfringens by Harry, Kathryn H, Zhou, Ruanbao, Kroos, Lee, Melville, Stephen B

    Published in Journal of Bacteriology (01-04-2009)
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  7. 7

    NanR, a Transcriptional Regulator That Binds to the Promoters of Genes Involved in Sialic Acid Metabolism in the Anaerobic Pathogen Clostridium perfringens by Therit, Blair, Cheung, Jackie K, Rood, Julian I, Melville, Stephen B

    Published in PloS one (21-07-2015)
    “…Among many other virulence factors, Clostridium perfringens produces three sialidases NanH, NanI and NanJ. NanH lacks a secretion signal peptide and is…”
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  8. 8
  9. 9

    Use of a Mariner-Based Transposon Mutagenesis System To Isolate Clostridium perfringens Mutants Deficient in Gliding Motility by Liu, Hualan, Bouillaut, Laurent, Sonenshein, Abraham L, Melville, Stephen B

    Published in Journal of Bacteriology (01-02-2013)
    “…Clostridium perfringens is an anaerobic Gram-positive pathogen that causes many human and animal diseases, including food poisoning and gas gangrene. C…”
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  10. 10

    Type IV pili‐dependent gliding motility in the Gram‐positive pathogen Clostridium perfringens and other Clostridia by Varga, John J., Nguyen, Van, O'Brien, David K., Rodgers, Katherine, Walker, Richard A., Melville, Stephen B.

    Published in Molecular microbiology (01-11-2006)
    “…Summary Bacteria can swim in liquid media by flagellar rotation and can move on surfaces via gliding or twitching motility. One type of gliding motility…”
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  11. 11

    Levels of germination proteins in Bacillus subtilis dormant, superdormant, and germinating spores by Chen, Yan, Ray, W Keith, Helm, Richard F, Melville, Stephen B, Popham, David L

    Published in PloS one (01-04-2014)
    “…Bacterial endospores exhibit extreme resistance to most conditions that rapidly kill other life forms, remaining viable in this dormant state for centuries or…”
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  12. 12

    Factors Contributing to Heat Resistance of Clostridium perfringens Endospores by Orsburn, Benjamin, Melville, Stephen B, Popham, David L

    Published in Applied and Environmental Microbiology (01-06-2008)
    “…The endospores formed by strains of type A Clostridium perfringens that produce the C. perfringens enterotoxin (CPE) are known to be more resistant to heat and…”
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  13. 13

    Effects of Clostridium perfringens Alpha-Toxin (PLC) and Perfringolysin O (PFO) on Cytotoxicity to Macrophages, on Escape from the Phagosomes of Macrophages, and on Persistence of C. perfringens in Host Tissues by O'BRIEN, David K, MELVILLE, Stephen B

    Published in Infection and Immunity (01-09-2004)
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  14. 14

    Holin-Dependent Secretion of the Large Clostridial Toxin TpeL by Clostridium perfringens by Saadat, Angela, Melville, Stephen B

    Published in Journal of bacteriology (23-03-2021)
    “…Large clostridial toxins (LCTs) are secreted virulence factors found in several species, including , , , and LCTs are large toxins that lack a secretion signal…”
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  15. 15

    Biochemistry and Physiology of the β Class Carbonic Anhydrase (Cpb) from Clostridium perfringens Strain 13 by Kumar, R. Siva Sai, Hendrick, William, Correll, Jared B, Patterson, Andrew D, Melville, Stephen B, Ferry, James G

    Published in Journal of Bacteriology (01-05-2013)
    “…The carbonic anhydrase (Cpb) from Clostridium perfringens strain 13, the only carbonic anhydrase encoded in the genome, was characterized both biochemically…”
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  16. 16

    The CcpA Protein Is Necessary for Efficient Sporulation and Enterotoxin Gene (cpe) Regulation in Clostridium perfringens by VARGA, John, STIREWALT, Veronica L, MELVILLE, Stephen B

    Published in Journal of Bacteriology (01-08-2004)
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  17. 17

    Mechanical limitation of bacterial motility mediated by growing cell chains by McMahon, Sean G., Melville, Stephen B., Chen, Jing

    Published in Biophysical journal (21-06-2022)
    “…Contrasting most known bacterial motility mechanisms, a bacterial sliding motility discovered in at least two gram-positive bacterial families does not depend…”
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  18. 18

    Mining transcriptome data: Utilization of environmentally regulated promoters for protein expression and purification in Clostridium perfringens by Soncini, Samantha R., Camper, Gary J., Melville, Stephen B.

    Published in Journal of microbiological methods (01-08-2022)
    “…Clostridium perfringens is a Gram-positive pathogen with low GC content. To identify genes that are transcribed at higher levels when the bacteria grow on a…”
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  19. 19

    Plasmalogen Biosynthesis by Anaerobic Bacteria: Identification of a Two-Gene Operon Responsible for Plasmalogen Production in Clostridium perfringens by Jackson, David R, Cassilly, Chelsi D, Plichta, Damian R, Vlamakis, Hera, Liu, Hualan, Melville, Stephen B, Xavier, Ramnik J, Clardy, Jon

    Published in ACS chemical biology (15-01-2021)
    “…Plasmalogens are vinyl ether-containing lipids produced by mammals and bacteria. The aerobic biosynthetic pathway in eukaryotes and bacteria is known, but the…”
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  20. 20

    Synergy in Polymicrobial Infections in a Mouse Model of Type 2 Diabetes by MASTROPAOLO, Matthew D, EVANS, Nicholas P, BYRNES, Meghan K, STEVENS, Ann M, ROBERTSON, John L, MELVILLE, Stephen B

    Published in Infection and Immunity (01-09-2005)
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