Search Results - "Stephen B. Melville"
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Expansion of the Clostridium perfringens toxin-based typing scheme
Published in Anaerobe (01-10-2018)“…Clostridium perfringens causes many different histotoxic and enterotoxic diseases in humans and animals as a result of its ability to produce potent protein…”
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Construction and Characterization of a Lactose-Inducible Promoter System for Controlled Gene Expression in Clostridium perfringens
Published in Applied and Environmental Microbiology (01-01-2011)“…Clostridium perfringens is a Gram-positive anaerobic pathogen which causes many diseases in humans and animals. While some genetic tools exist for working with…”
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Cyclic Di-GMP Binding by an Assembly ATPase (PilB2) and Control of Type IV Pilin Polymerization in the Gram-Positive Pathogen Clostridium perfringens
Published in Journal of bacteriology (15-05-2017)“…The Gram-positive pathogen possesses type IV pili (TFP), which are extracellular fibers that are polymerized from a pool of pilin monomers in the cytoplasmic…”
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Type IV Pili and the CcpA Protein Are Needed for Maximal Biofilm Formation by the Gram-Positive Anaerobic Pathogen Clostridium perfringens
Published in Infection and Immunity (01-11-2008)“…The predominant organizational state of bacteria in nature is biofilms. Biofilms have been shown to increase bacterial resistance to a variety of stresses. We…”
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Changes in the expression of genes encoding type IV pili-associated proteins are seen when Clostridium perfringens is grown in liquid or on surfaces
Published in BMC genomics (14-01-2020)“…Clostridium perfringens is a Gram-positive anaerobic pathogen that causes multiple diseases in humans and animals. C. perfringens lack flagella but have type…”
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Sporulation and Enterotoxin (CPE) Synthesis Are Controlled by the Sporulation-Specific Sigma Factors SigE and SigK in Clostridium perfringens
Published in Journal of Bacteriology (01-04-2009)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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7
NanR, a Transcriptional Regulator That Binds to the Promoters of Genes Involved in Sialic Acid Metabolism in the Anaerobic Pathogen Clostridium perfringens
Published in PloS one (21-07-2015)“…Among many other virulence factors, Clostridium perfringens produces three sialidases NanH, NanI and NanJ. NanH lacks a secretion signal peptide and is…”
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Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens
Published in Genome Research (01-08-2006)“…Clostridium perfringens is a Gram-positive, anaerobic spore-forming bacterium commonly found in soil, sediments, and the human gastrointestinal tract. C…”
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Use of a Mariner-Based Transposon Mutagenesis System To Isolate Clostridium perfringens Mutants Deficient in Gliding Motility
Published in Journal of Bacteriology (01-02-2013)“…Clostridium perfringens is an anaerobic Gram-positive pathogen that causes many human and animal diseases, including food poisoning and gas gangrene. C…”
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Type IV pili‐dependent gliding motility in the Gram‐positive pathogen Clostridium perfringens and other Clostridia
Published in Molecular microbiology (01-11-2006)“…Summary Bacteria can swim in liquid media by flagellar rotation and can move on surfaces via gliding or twitching motility. One type of gliding motility…”
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11
Levels of germination proteins in Bacillus subtilis dormant, superdormant, and germinating spores
Published in PloS one (01-04-2014)“…Bacterial endospores exhibit extreme resistance to most conditions that rapidly kill other life forms, remaining viable in this dormant state for centuries or…”
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Factors Contributing to Heat Resistance of Clostridium perfringens Endospores
Published in Applied and Environmental Microbiology (01-06-2008)“…The endospores formed by strains of type A Clostridium perfringens that produce the C. perfringens enterotoxin (CPE) are known to be more resistant to heat and…”
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Effects of Clostridium perfringens Alpha-Toxin (PLC) and Perfringolysin O (PFO) on Cytotoxicity to Macrophages, on Escape from the Phagosomes of Macrophages, and on Persistence of C. perfringens in Host Tissues
Published in Infection and Immunity (01-09-2004)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Holin-Dependent Secretion of the Large Clostridial Toxin TpeL by Clostridium perfringens
Published in Journal of bacteriology (23-03-2021)“…Large clostridial toxins (LCTs) are secreted virulence factors found in several species, including , , , and LCTs are large toxins that lack a secretion signal…”
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Biochemistry and Physiology of the β Class Carbonic Anhydrase (Cpb) from Clostridium perfringens Strain 13
Published in Journal of Bacteriology (01-05-2013)“…The carbonic anhydrase (Cpb) from Clostridium perfringens strain 13, the only carbonic anhydrase encoded in the genome, was characterized both biochemically…”
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The CcpA Protein Is Necessary for Efficient Sporulation and Enterotoxin Gene (cpe) Regulation in Clostridium perfringens
Published in Journal of Bacteriology (01-08-2004)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Mechanical limitation of bacterial motility mediated by growing cell chains
Published in Biophysical journal (21-06-2022)“…Contrasting most known bacterial motility mechanisms, a bacterial sliding motility discovered in at least two gram-positive bacterial families does not depend…”
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Mining transcriptome data: Utilization of environmentally regulated promoters for protein expression and purification in Clostridium perfringens
Published in Journal of microbiological methods (01-08-2022)“…Clostridium perfringens is a Gram-positive pathogen with low GC content. To identify genes that are transcribed at higher levels when the bacteria grow on a…”
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Plasmalogen Biosynthesis by Anaerobic Bacteria: Identification of a Two-Gene Operon Responsible for Plasmalogen Production in Clostridium perfringens
Published in ACS chemical biology (15-01-2021)“…Plasmalogens are vinyl ether-containing lipids produced by mammals and bacteria. The aerobic biosynthetic pathway in eukaryotes and bacteria is known, but the…”
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Synergy in Polymicrobial Infections in a Mouse Model of Type 2 Diabetes
Published in Infection and Immunity (01-09-2005)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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