Search Results - "Stephen, Douglas"
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Team IHMC's Lessons Learned from the DARPA Robotics Challenge Trials
Published in Journal of field robotics (01-03-2015)“…This article is a summary of the experiences of the Florida Institute for Human & Machine Cognition (IHMC) team during the DARPA Robotics Challenge (DRC)…”
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2
The salience of social context, opioid antagonist use, and prior opioid exposure as determinants of fatal and non-fatal opioid overdoses
Published in Health & place (01-01-2023)“…This study examines the salience of social context for opioid overdoses in Boston from 2014 to 2019. Longitudinal negative binomial models with random effects…”
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Epoxyeicosatrienoic acids function as selective, endogenous antagonists of native thromboxane receptors: identification of a novel mechanism of vasodilation
Published in The Journal of pharmacology and experimental therapeutics (01-01-2009)“…Epoxy- and dihydroxy-eicosatrienoic acids (EETs and DHETs) are vasoactive cytochrome P450 metabolites of arachidonic acid. Interestingly, however, the…”
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Multimodal thromboprophylaxis in low-risk patients undergoing lower limb arthroplasty: A retrospective observational cohort analysis of 1400 patients with ultrasound screening
Published in Journal of orthopaedic surgery (Hong Kong) (01-01-2020)“…Purpose: This study reports the results of a multimodal thromboprophylaxis protocol for lower limb arthroplasty involving risk stratification, intraoperative…”
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Acute Depletion of Endothelial β3-Integrin Transiently Inhibits Tumor Growth and Angiogenesis in Mice
Published in Circulation research (03-01-2014)“…RATIONALE:The dramatic upregulation of αvβ3-integrin that occurs in the vasculature during tumor growth has long suggested that the endothelial expression of…”
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Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase
Published in Bioorganic & medicinal chemistry letters (15-06-2013)“…1-(1,3,5-Triazin-yl)piperidine-4-carboxamide inhibitors of soluble epoxide hydrolase were identified from high through-put screening using encoded library…”
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Congestive heart failure and expression of myocardial urotensin II
Published in The Lancet (British edition) (08-06-2002)“…Human urotensin II has several cardiovascular actions, including potent vasoactive, and cardiac inotropic and hypertropic properties. Our aim was to ascertain…”
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Lysophosphatidylcholine induces inflammatory activation of human coronary artery smooth muscle cells
Published in Molecular and cellular biochemistry (01-01-2007)“…Lysophosphatidylcholine (LPC) is the major bioactive lipid component of oxidized LDL, thought to be responsible for many of the inflammatory effects of…”
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NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation
Published in Journal of enzyme inhibition and medicinal chemistry (01-02-2013)“…NADPH oxidase isoform-2 (NOX2) generates reactive oxygen species (ROS) that contribute to neurodegenerative and cardiovascular pathologies. However, validation…”
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The Work of Adult and Pediatric Intensive Care Unit Nurses
Published in Nursing research (New York) (01-01-2013)“…BACKGROUND:Researchers have used various methods to describe and quantify the work of nurses. Many of these studies were focused on nursing in general care…”
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Increased expression of urotensin II and its cognate receptor GPR14 in atherosclerotic lesions of the human aorta
Published in Atherosclerosis (01-09-2004)“…Urotensin II (U-II), a novel vasoactive peptide, possesses a wide range of cardiovascular effects. U-II binds a seven transmembrane spanning G-protein coupled…”
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Urotensin-II blockade with SB-611812 attenuates cardiac dysfunction in a rat model of coronary artery ligation
Published in Journal of molecular and cellular cardiology (01-08-2006)“…Expression of urotensin II (UII) is significantly elevated in the hearts of patients with congestive heart failure (CHF). Recent reports have also shown…”
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Conducting an efficient proactive risk assessment prior to CPOE implementation in an intensive care unit
Published in International journal of medical informatics (Shannon, Ireland) (01-01-2013)“…Abstract Purpose To develop, conduct, and evaluate a proactive risk assessment (PRA) of the design and implementation of CPOE in an ICU. Methods We developed a…”
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Robotic and navigation systems in orthopaedic surgery: how much do our patients understand?
Published in Clinics in orthopedic surgery (01-12-2014)“…Technology in orthopaedic surgery has become more widespread in the past 20 years, with emerging evidence of its benefits in arthroplasty. Although patients…”
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Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14
Published in Nature (London) (16-09-1999)“…Urotensin-II (U-II) is a vasoactive 'somatostatin-like' cyclic peptide which was originally isolated from fish spinal cords, and which has recently been cloned…”
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Differential vasoconstrictor activity of human urotensin‐II in vascular tissue isolated from the rat, mouse, dog, pig, marmoset and cynomolgus monkey
Published in British journal of pharmacology (01-12-2000)“…Urotensin‐II (U‐II) and its G‐protein‐coupled receptor, GPR14, are expressed within mammalian cardiac and peripheral vascular tissue and, as such, may regulate…”
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Human urotensin‐II is an endothelium‐dependent vasodilator in rat small arteries
Published in British journal of pharmacology (01-08-2000)“…The possible role of the endothelium in modulating responses to human urotensin‐II (U‐II) was investigated using isolated segments of rat thoracic aorta, small…”
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Expression of urotensin-II in human coronary atherosclerosis
Published in Peptides (New York, N.Y. : 1980) (01-12-2005)“…The vasoactive peptide urotensin-II (U-II) is best known for its ability to regulate peripheral vascular and cardiac contractile function in vivo, and recent…”
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Effects of p38 MAPK Inhibitor on Angiotensin II-Dependent Hypertension, Organ Damage, and Superoxide Anion Production
Published in Journal of cardiovascular pharmacology (01-06-2007)“…Angiotensin II (Ang II) activates p38 mitogen-activated protein kinase (p38 MAPK) and increases reactive oxygen species (ROS), but the nature of the…”
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Potent vasodilator responses to human urotensin-II in human pulmonary and abdominal resistance arteries
Published in American journal of physiology. Heart and circulatory physiology (01-02-2001)“…The peptide human urotensin-II (hUT-II) and its receptor have recently been cloned. The vascular function of this peptide in humans, however, has yet to be…”
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