Search Results - "Stephanie, Beurlet"

Pathogenic Escherichia coli in Dogs Reveals the Predominance of ST372 and the Human-Associated ST73 Extra-Intestinal Lineages by Valat, Charlotte, Drapeau, Antoine, Beurlet, Stéphanie, Bachy, Véronique, Boulouis, Henri-Jean, Pin, Raphaëlle, Cazeau, Géraldine, Madec, Jean-Yves, Haenni, Marisa

“…is a ubiquitous commensal and pathogen that has also been recognized as a multi-sectoral indicator of antimicrobial resistance (AMR). Given that latter focus,…”
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Association between quantitative bacterial culture of bronchoalveolar lavage fluid and antibiotic requirement in dogs with lower respiratory tract signs by Lebastard, Matthieu, Beurlet‐Lafarge, Stephanie, Gomes, Eymeric, Le Boedec, Kevin

“…Background Historically, positive bacterial cultures from the lower respiratory tract (LRT) have been considered clinically relevant when quantitative…”
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First Evidence of Natural SARS-CoV-2 Infection in Domestic Rabbits by Fritz, Matthieu, de Riols de Fonclare, Daphné, Garcia, Déborah, Beurlet, Stéphanie, Becquart, Pierre, Rosolen, Serge G, Briend-Marchal, Alexandra, Leroy, Eric M

“…We tested 144 pet rabbits sampled in France between November 2020 and June 2021 for antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
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European multicenter study on antimicrobial resistance in bacteria isolated from companion animal urinary tract infections by Marques, Cátia, Gama, Luís Telo, Belas, Adriana, Bergström, Karin, Beurlet, Stéphanie, Briend-Marchal, Alexandra, Broens, Els M, Costa, Marta, Criel, Delphine, Damborg, Peter, van Dijk, Marloes A M, van Dongen, Astrid M, Dorsch, Roswitha, Espada, Carmen Martin, Gerber, Bernhard, Kritsepi-Konstantinou, Maria, Loncaric, Igor, Mion, Domenico, Misic, Dusan, Movilla, Rebeca, Overesch, Gudrun, Perreten, Vincent, Roura, Xavier, Steenbergen, Joachim, Timofte, Dorina, Wolf, Georg, Zanoni, Renato Giulio, Schmitt, Sarah, Guardabassi, Luca, Pomba, Constança

“…There is a growing concern regarding the increase of antimicrobial resistant bacteria in companion animals. Yet, there are no studies comparing the resistance…”
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BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome by Gorombei, Petra, Guidez, Fabien, Ganesan, Saravanan, Chiquet, Mathieu, Pellagatti, Andrea, Goursaud, Laure, Tekin, Nilgun, Beurlet, Stephanie, Patel, Satyananda, Guerenne, Laura, Le Pogam, Carole, Setterblad, Niclas, de la Grange, Pierre, LeBoeuf, Christophe, Janin, Anne, Noguera, Maria-Elena, Sarda-Mantel, Laure, Merlet, Pascale, Boultwood, Jacqueline, Konopleva, Marina, Andreeff, Michael, West, Robert, Pla, Marika, Adès, Lionel, Fenaux, Pierre, Krief, Patricia, Chomienne, Christine, Omidvar, Nader, Padua, Rose Ann

“…During transformation, myelodysplastic syndromes (MDS) are characterized by reducing apoptosis of bone marrow (BM) precursors. Mouse models of high risk…”
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Engineering mouse models with myelodysplastic syndrome human candidate genes; how relevant are they? by Beurlet, Stephanie, Chomienne, Christine, Padua, Rose Ann

“…Myelodysplastic syndromes represent particularly challenging hematologic malignancies that arise from a large spectrum of genetic events resulting in a disease…”
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GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways by Guerenne, Laura, Beurlet, Stéphanie, Said, Mohamed, Gorombei, Petra, Le Pogam, Carole, Guidez, Fabien, de la Grange, Pierre, Omidvar, Nader, Vanneaux, Valérie, Mills, Ken, Mufti, Ghulam J, Sarda-Mantel, Laure, Noguera, Maria Elena, Pla, Marika, Fenaux, Pierre, Padua, Rose Ann, Chomienne, Christine, Krief, Patricia

“…In spite of the recent discovery of genetic mutations in most myelodysplasic (MDS) patients, the pathophysiology of these disorders still remains poorly…”
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Identification of JAK2 mutations in canine primary polycythemia by Beurlet, Stephanie, Krief, Patricia, Sansonetti, Arnaud, Briend-Marchal, Alexandra, Kiladjian, Jean-Jacques, Padua, Rose Ann, Chomienne, Christine, Cassinat, Bruno

“…Objective Primary polycythemia in dogs is classified as a myeloproliferative syndrome with a chronic progressive course and unspecific symptoms. Diagnosis is…”
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C-reactive protein concentration has limited value in the diagnosis of meningoencephalitis of unknown origin in dogs by Cavalerie, Robin, Santos, Alejandro Comesaña Dos, Leonardi, Hugo, Blond, Laurent, Beurlet, Stéphanie, Dumont, Renaud, Piazza, Stéphanie

“…To evaluate blood and cerebrospinal fluid (CSF) concentrations of C-reactive protein (CRP) in dogs with meningoencephalitis of unknown origin (MUO); to…”
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Suppurative spinal meningomyelitis in a dog with intra‐neutrophilic cerebrospinal fluid cells Ehrlichia canis morulae by Frankar, Hadrien, Le Boedec, Kevin, Beurlet, Stéphanie, Cauzinille, Laurent

“…A 2‐year‐old castrated male Creole Shepherd mixed dog was presented for non‐ambulatory paraparesis of the pelvic limbs. The magnetic resonance imaging and…”
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Comparison of STA‐NeoPTimal (Stago) and STA‐Neoplastine CI Plus (Stago) thromboplastin reagents using a STA Satellite Max analyzer to measure prothrombin times in dogs by Beurlet, Stéphanie, Coisnon, Camille, Nguyen, Trung Thanh, Richet, Marine, Carlo, Audrey, Briend‐Marchal, Alexandra

“…Background Different thromboplastins are available to measure prothrombin time (PT). Stago coagulation analyzers and reagents are currently used in veterinary…”
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Determination of morphological, biometric and biochemical susceptibilities in healthy Eurasier dogs with suspected inherited glaucoma by Boillot, Thomas, Rosolen, Serge G, Dulaurent, Thomas, Goulle, Frédéric, Thomas, Philippe, Isard, Pierre-François, Azoulay, Thierry, Lafarge-Beurlet, Stéphanie, Woods, Mike, Lavillegrand, Sylvie, Ivkovic, Ivana, Neveux, Nathalie, Sahel, José-Alain, Picaud, Serge, Froger, Nicolas

“…In both humans and dogs, the primary risk factor for glaucoma is high intraocular pressure (IOP), which may be caused by iridocorneal angle (ICA)…”
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Primary bronchial carcinoma associated with bone marrow metastasis and paraneoplastic monoclonal gammopathy in a cat by Cervone, Mario, Beurlet, Stéphanie

“…Herein we describe an unusual metastatic pattern and paraneoplastic manifestation of a bronchial carcinoma in a cat. An 8 year-old cat presented with a…”
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DNA and All-Trans Retinoic Acid as Immunotherapy or Add-on Adjuvants to 5-Azacytidine In Myelodysplastic Syndromes by Le Pogam, Carole, Krief, Patricia, Beurlet, Stéphanie, Reboul, Murielle, West, Robert, Pla, Marika, Charron, Dominique, Fenaux, Pierre, Chomienne, Christine, Padua, Rose Ann

“…Abstract 2938 Myelodysplastic syndromes (MDS) are clonal stem cell hematological disorders characterized by ineffective hematopoiesis leading to cytopenia,…”
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BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells by Beurlet, Stephanie, Omidvar, Nader, Gorombei, Petra, Krief, Patricia, Le Pogam, Carole, Setterblad, Niclas, de la Grange, Pierre, Leboeuf, Christophe, Janin, Anne, Noguera, Maria-Elena, Hervatin, Florence, Sarda-Mantel, Laure, Konopleva, Marina, Andreeff, Michael, Tu, Andrea W., Fan, Alice C., Felsher, Dean W., Whetton, Anthony, Pla, Marika, West, Robert, Fenaux, Pierre, Chomienne, Christine, Padua, Rose Ann

“…Myelodysplastic syndrome (MDS) transforms into an acute myelogenous leukemia (AML) with associated increased bone marrow (BM) blast infiltration. Using a…”
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Reactive oxygen species, DNA damage, and error-prone repair : A model for genomic instability with progression in myeloid leukemia? by RASSOOL, Feyruz V, GAYMES, Terry J, MULTI, Ghulam J, PADUA, Rose Ann, OMIDVAR, Nader, BRADY, Nicola, BEURLET, Stephanie, PLA, Marika, REBOUL, Murielle, LEA, Nicholas, CHOMIENNE, Christine, THOMAS, Nicholas S. B

“…Myelodysplastic syndromes (MDS) comprise a heterogeneous group of disorders characterized by ineffective hematopoiesis, with an increased propensity to develop…”
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BCL-2 and Mutant NRAS Interact Physically and Functionally in a Mouse Model of Progressive Myelodysplasia by OMIDVAR, Nader, KOGAN, Scott, SETTERBLAD, Niclas, FELSHER, Dean, LAGASSE, Eric, MOHAMEDALI, Azim, THOMAS, N. Shaun B, FENAUX, Pierre, FONTENAY, Michaela, PLA, Marika, MUFTI, Ghulam J, WEISSMAN, Irving, BEURLET, Stephanie, CHOMIENNE, Christine, PADUA, Rose Ann, LE POGAM, Carole, JANIN, Anne, WEST, Robert, NOGUERA, Maria-Elena, REBOUL, Murielle, SOULIE, Annie, LEBOEUF, Christophe

“…Myelodysplastic syndromes (MDS) are clonal stem cell hematologic disorders that evolve to acute myeloid leukemia (AML) and thus model multistep leukemogenesis…”
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BCL-2 Inhibition with ABT-737 Prolongs Survival in an NRAS/BCL2-Mediated MOUSE MODEL of Myelodyspastic Syndrome (MDS) Progressing to ACUTE Myelogenous Leukemia (AML) by Targeting Leukemia Initiating CELLS by Gorombei, Petra, Stephanie, Beurlet, Omidvar, Nader, Patricia, Krief, Carole, Le Pogam, de la Grange, Pierre, Christophe, Leboeuf, Janin, Anne, Maria-Elena, Noguera, Konopleva, Marina, Andreeff, Michael, Marika, Pla, Robert, West, Fenaux, Pierre, Chomienne, Christine, Padua, Rose Ann

“…Abstract 678 BCL-2 activation plays a role in the progression of MDS to AML and BCL 2 inhibition may represent a therapeutic target in such patients. Using our…”
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Mutant BCL2 Co-Operates with CBFβ/PEBP2β-MYH11 to Promote Expansion of Leukemia Initiating Cells with a Predominantly Pro-Apoptotic Mechanism Via Recruitment of Ras-GTP In a Mouse Model of Progressive Acute Myeloid Leukemia by Omidvar, Nader, Pogam, Carole Le, Beurlet, Stephanie, Noguera, Maria-Elena, Janin, Ann, Kogan, Scott C., Weissman, Irving L., Pla, Marika, Chomienne, Christine, Padua, Rose Ann

“…Abstract 1050 Mutations and translocation of the core binding factor complexes frequently co-operate with other lesions in Acute Myeloid Leukemia (AML). In…”
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NRAS:BCL-2 Complex Localization Determines Anti-Apoptotic Features Associated with Progressive Disease in Myelodysplastic Syndromes (MDS) by Padua, Rose Ann, Le Pogam, Carole, Krief, Patricia, Beurlet, Stephanie, Cassinat, Bruno, Cavé, Hélène, Kosmider, Olivier, Setterblad, Niclas, Leboeuf, Christophe, Sarda-Mantel, Laure, Hervatin, Florence, Merlet, Pascal, Noguera, Maria-Elena, Janin, Anne, Pla, Marika, Fontenay, Michaela, Ades, Lionel, Fenaux, Pierre, Chomienne, Christine, Omidvar, Nader

“…Abstract 3835 Activation of the RAS pathway plays an important role in the pathogenesis of myeloid malignancies. RAS mutations occur in some 10% of MDS and…”
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