Search Results - "Stephan Gruber"
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Multilayer chromosome organization through DNA bending, bridging and extrusion
Published in Current opinion in microbiology (01-12-2014)“…Highlights • Bacterial nucleoids are compact, dynamic and highly organized structures. • Abundant DNA bending proteins cause local folding of chromosomal DNA…”
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Ground subsidence and heave over permafrost: hourly time series reveal interannual, seasonal and shorter-term movement caused by freezing, thawing and water movement
Published in The cryosphere (30-04-2020)“…Heave and subsidence of the ground surface can offer insight into processes of heat and mass transfer in freezing and thawing soils. Additionally, subsidence…”
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Kite Proteins: a Superfamily of SMC/Kleisin Partners Conserved Across Bacteria, Archaea, and Eukaryotes
Published in Structure (London) (01-12-2015)“…SMC/kleisin complexes form elongated annular structures, which are critical for chromosome segregation, genome maintenance, and the regulation of gene…”
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Recruitment of Condensin to Replication Origin Regions by ParB/SpoOJ Promotes Chromosome Segregation in B. subtilis
Published in Cell (15-05-2009)“…Proper segregation of DNA replication products is essential in all cells. In Bacillus subtilis, two protein complexes have been implicated in this process: the…”
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Environmental controls of frost cracking revealed through in situ acoustic emission measurements in steep bedrock
Published in Geophysical research letters (16-05-2013)“…Frost cracking, the breakdown of rock by freezing, is one of the most important mechanical weathering processes acting on Earth's surface. Insights on the…”
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DNA tension-modulated translocation and loop extrusion by SMC complexes revealed by molecular dynamics simulations
Published in Nucleic acids research (20-05-2022)“…Structural Maintenance of Chromosomes (SMC) complexes play essential roles in genome organization across all domains of life. To determine how the activities…”
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DNA-segment-capture model for loop extrusion by structural maintenance of chromosome (SMC) protein complexes
Published in Nucleic acids research (26-07-2019)“…Cells possess remarkable control of the folding and entanglement topology of long and flexible chromosomal DNA molecules. It is thought that structural…”
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Transient DNA Occupancy of the SMC Interarm Space in Prokaryotic Condensin
Published in Molecular cell (25-07-2019)“…Multi-subunit SMC ATPases control chromosome superstructure and DNA topology, presumably by DNA translocation and loop extrusion. Chromosomal DNA is entrapped…”
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Kinematics of steep bedrock permafrost
Published in Journal of Geophysical Research: Earth Surface (01-03-2012)“…The mechanisms that control climate‐dependent rockfall from permafrost mountain slopes are currently poorly understood. In this study, we present the results…”
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Closing the cohesin ring: Structure and function of its Smc3-kleisin interface
Published in Science (American Association for the Advancement of Science) (21-11-2014)“…Through their association with a kleisin subunit (Scc1), cohesin's Smc1 and Smc3 subunits are thought to form tripartite rings that mediate sister chromatid…”
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Design analysis of a hybrid storage concept combining Ruths steam storage and latent thermal energy storage
Published in Applied energy (01-10-2019)“…[Display omitted] •New hybrid thermal energy storage concept for storing steam and electrical energy.•Analysis by variation of number and properties of…”
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VirB, a transcriptional activator of virulence in Shigella flexneri, uses CTP as a cofactor
Published in Communications biology (25-11-2023)“…VirB is a transcriptional activator of virulence in the gram-negative bacterium Shigella flexneri encoded by the large invasion plasmid, pINV. It counteracts…”
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Structure of Full-Length SMC and Rearrangements Required for Chromosome Organization
Published in Molecular cell (20-07-2017)“…Multi-subunit SMC complexes control chromosome superstructure and promote chromosome disjunction, conceivably by actively translocating along DNA double…”
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Transferring Cryosphere Knowledge between Mountains Globally: A Case Study of Western Canadian Mountains, the European Alps and the Scandes
Published in Revue de géographie alpine (01-01-2023)“…Permafrost is present in mountains globally, yet most research has been focussed in the small area covered by the European Alps. This paper presents a method…”
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Direct observation of a crescent-shape chromosome in expanded Bacillus subtilis cells
Published in Nature communications (28-03-2024)“…Bacterial chromosomes are folded into tightly regulated three-dimensional structures to ensure proper transcription, replication, and segregation of the…”
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Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding
Published in The EMBO journal (02-08-2021)“…Eukaryotic cells employ three SMC (structural maintenance of chromosomes) complexes to control DNA folding and topology. The Smc5/6 complex plays roles in DNA…”
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Author Correction: Direct observation of a crescent-shape chromosome in expanded Bacillus subtilis cells
Published in Nature communications (16-04-2024)Get full text
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SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae
Published in Molecular microbiology (01-08-2011)“…Summary Segregation of replicated chromosomes is an essential process in all organisms. How bacteria, such as the oval‐shaped human pathogen Streptococcus…”
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Shaikh, Anwar. Capitalism: Competition, Conflict and Crises. Nueva York: Oxford University Press, 2016, 1024 pp
Published in Economía (Lima) (01-10-2017)Get full text
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