Search Results - "Stephan, Joseph"
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The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3
Published in Neuron (Cambridge, Mass.) (17-06-2015)“…Consolidation of long-term memories depends on de novo protein synthesis. Several translational regulators have been identified, and their contribution to the…”
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Emission abatement: Untangling the impacts of the EU ETS and the economic crisis
Published in Energy economics (01-05-2015)“…In this study we use historical emission data from installations under the European Union Emissions Trading System (EU ETS) to evaluate the impact of this…”
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Lactate Mediates the Effects of Exercise on Learning and Memory through SIRT1-Dependent Activation of Hippocampal Brain-Derived Neurotrophic Factor (BDNF)
Published in The Journal of neuroscience (27-03-2019)“…Exercise promotes learning and memory formation. These effects depend on increases in hippocampal BDNF, a growth factor associated with cognitive improvement…”
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Policy stringency under the European Union Emission trading system and its impact on technological change in the energy sector
Published in Energy policy (01-06-2018)“…In this study, we use patent count data for overall Climate Change Mitigation Technologies, and for those related to energy production and distribution to…”
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Climate change mitigation and the role of technological change: Impact on selected headline targets of Europe's 2020 climate and energy package
Published in Renewable & sustainable energy reviews (01-02-2018)“…The European Union launched a set of policies as part of its 2020 climate and energy package aimed at meeting its 20/20/20 headline targets for smart,…”
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Structural insights into the binding mechanism of Clr4 methyltransferase to H3K9 methylated nucleosome
Published in Scientific reports (05-03-2024)“…The establishment and maintenance of heterochromatin, a specific chromatin structure essential for genomic stability and regulation, rely on intricate…”
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The CPEB3 Protein Is a Functional Prion that Interacts with the Actin Cytoskeleton
Published in Cell reports (Cambridge) (23-06-2015)“…The mouse cytoplasmic polyadenylation element-binding protein 3 (CPEB3) is a translational regulator implicated in long-term memory maintenance. Invertebrate…”
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Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2019)“…Chronic stress promotes depression in some individuals, but has no effect in others. Susceptible individuals exhibit social avoidance and anxious behavior and…”
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Exercise factors as potential mediators of cognitive rehabilitation following traumatic brain injury
Published in Current opinion in neurology (01-12-2019)“…To summarize what is known about how exercise mediates cognitive rehabilitation post traumatic brain injury (TBI). TBI is a devastating condition that leads to…”
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10
Tor and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagy
Published in Proceedings of the National Academy of Sciences - PNAS (06-10-2009)“…Macroautophagy (or autophagy) is a conserved degradative pathway that has been implicated in a number of biological processes, including organismal aging,…”
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Exercise Factors Released by the Liver, Muscle, and Bones Have Promising Therapeutic Potential for Stroke
Published in Frontiers in neurology (24-05-2021)“…Stroke is one of the leading causes of death and disability in the world. Stroke not only affects the patients, but also their families who serve as the…”
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12
The effects of moratoriums on hotel building: an anti-tourism measure, or rather protection for local incumbents?
Published in Applied economics letters (16-08-2022)“…In July 2015, the newly elected City Council of Barcelona approved a moratorium on the building of hotels. This study empirically evaluates its effect on hotel…”
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Trabecular bone organoids: a micron-scale ‘humanised’ prototype designed to study the effects of microgravity and degeneration
Published in NPJ microgravity (21-05-2021)“…Bone is a highly responsive organ, which continuously adapts to the environment it is subjected to in order to withstand metabolic demands. These events are…”
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Cross-border Portfolio Investment Networks and Indicators for Financial Crises
Published in Scientific reports (10-02-2014)“…Cross-border equity and long-term debt securities portfolio investment networks are analysed from 2002 to 2012, covering the 2008 global financial crisis. They…”
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15
Epigenetic changes in diabetes
Published in Neuroscience letters (20-06-2016)“…The incidence of diabetes is increasing worldwide. Diabetes is quickly becoming one of the leading causes of death. Diabetes is a genetic disease; however, the…”
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Methionine mediates resilience to chronic social defeat stress by epigenetic regulation of NMDA receptor subunit expression
Published in Psychopharmacology (01-10-2020)“…Rationale Previous studies suggested that methionine (Met) levels are decreased in depressed patients. However, whether the decrease in this amino acid is…”
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Nicotine induces resilience to chronic social defeat stress in a mouse model of water pipe tobacco exposure by activating BDNF signaling
Published in Behavioural brain research (16-03-2020)“…The purpose of this study was to investigate how nicotine in the context of water pipe tobacco smoking (WTS) affects depression and anxiety-like behaviors…”
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An Evolutionary Proteomics Approach Identifies Substrates of the cAMP-Dependent Protein Kinase
Published in Proceedings of the National Academy of Sciences - PNAS (27-09-2005)“…Protein kinases are important mediators of much of the signal transduction that occurs in eukaryotic cells. Unfortunately, the identification of protein kinase…”
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Branched-chain amino acids mediate resilience to chronic social defeat stress by activating BDNF/TRKB signaling
Published in Neurobiology of stress (01-11-2019)“…How individuals respond to chronic stress varies. Susceptible individuals ultimately develop depression; whereas resilient individuals live normally. In this…”
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Autophagy regulates the release of exercise factors and their beneficial effects on spatial memory recall
Published in Heliyon (01-04-2023)“…Exercise promotes learning and memory recall as well as rescues cognitive decline associated with aging. The positive effects of exercise are mediated by…”
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