Search Results - "Stephan, Holger"

Nanomaterials: Applications in Cancer Imaging and Therapy by Barreto, José A., O'Malley, William, Kubeil, Manja, Graham, Bim, Stephan, Holger, Spiccia, Leone

“…The application of nanomaterials (NMs) in biomedicine is increasing rapidly and offers excellent prospects for the development of new non‐invasive strategies…”
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Zwitterionic-Coated "Stealth" Nanoparticles for Biomedical Applications: Recent Advances in Countering Biomolecular Corona Formation and Uptake by the Mononuclear Phagocyte System by García, Karina Pombo, Zarschler, Kristof, Barbaro, Lisa, Barreto, José A., O'Malley, William, Spiccia, Leone, Stephan, Holger, Graham, Bim

“…Nanoparticles represent highly promising platforms for the development of imaging and therapeutic agents, including those that can either be detected via more…”
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Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications by Zarschler, Kristof, Rocks, Louise, Licciardello, Nadia, Boselli, Luca, Polo, Ester, Garcia, Karina Pombo, De Cola, Luisa, Stephan, Holger, Dawson, Kenneth A

“…Abstract Ultrasmall nanoparticulate materials with core sizes in the 1-3 nm range bridge the gap between single molecules and classical, larger-sized…”
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Polyoxometalates as Versatile Enzyme Inhibitors by Stephan, Holger, Kubeil, Manja, Emmerling, Franziska, Müller, Christa E.

“…Polyoxometalates (POMs) are inorganic cluster compounds that have been shown to possess a number of pharmacological properties, including antidiabetic,…”
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Nanoparticles for radiooncology: Mission, vision, challenges by Kunz-Schughart, Leoni A, Dubrovska, Anna, Peitzsch, Claudia, Ewe, Alexander, Aigner, Achim, Schellenburg, Samuel, Muders, Michael H, Hampel, Silke, Cirillo, Giuseppe, Iemma, Francesca, Tietze, Rainer, Alexiou, Christoph, Stephan, Holger, Zarschler, Kristof, Vittorio, Orazio, Kavallaris, Maria, Parak, Wolfgang J, Mädler, Lutz, Pokhrel, Suman

“…Abstract Cancer is one of the leading non-communicable diseases with highest mortality rates worldwide. About half of all cancer patients receive radiation…”
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High-yield production of functional soluble single-domain antibodies in the cytoplasm of Escherichia coli by Zarschler, Kristof, Witecy, Stefanie, Kapplusch, Franz, Foerster, Christian, Stephan, Holger

“…For their application in the area of diagnosis and therapy, single-domain antibodies (sdAbs) offer multiple advantages over conventional antibodies and…”
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Studies of Carbon Monoxide Release from Ruthenium(II) Bipyridine Carbonyl Complexes upon UV-Light Exposure by Kubeil, Manja, Vernooij, Robbin R, Kubeil, Clemens, Wood, Bayden R, Graham, Bim, Stephan, Holger, Spiccia, Leone

“…The UV-light-induced CO release characteristics of a series of ruthenium­(II) carbonyl complexes of the form trans-Cl­[RuLCl2(CO)2] (L =…”
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Immunotheranostic target modules for imaging and navigation of UniCAR T-cells to strike FAP-expressing cells and the tumor microenvironment by Loureiro, Liliana R, Hoffmann, Lydia, Neuber, Christin, Rupp, Luise, Arndt, Claudia, Kegler, Alexandra, Kubeil, Manja, Hagemeyer, Christoph E, Stephan, Holger, Schmitz, Marc, Feldmann, Anja, Bachmann, Michael

“…Chimeric antigen receptor (CAR) T-cells are a promising approach in cancer immunotherapy, particularly for treating hematologic malignancies. Yet, their…”
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Contemporary Synthesis of Ultrasmall (sub‐10 nm) Upconverting Nanomaterials by Joshi, Tanmaya, Mamat, Constantin, Stephan, Holger

“…Due to their unique photophysical properties, upconverting nanoparticles (UCNPs), i. e. particles capable of converting near‐infrared (NIR) photons into…”
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The Significance of Comparative Genomics in Modern Evolutionary Venomics by Drukewitz, Stephan Holger, von Reumont, Björn Marcus

“…Venoms evolved convergently in diverse animal lineages as key adaptations that increase the evolutionary fitness of species which are manifold employed for…”
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Chelators for Treatment of Iron and Copper Overload: Shift from Low-Molecular-Weight Compounds to Polymers by Hruby, Martin, Martínez, Irma Ivette Santana, Stephan, Holger, Pouckova, Pavla, Benes, Jiri, Stepanek, Petr

“…Iron and copper are essential micronutrients needed for the proper function of every cell. However, in excessive amounts, these elements are toxic, as they may…”
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A Dipteran's Novel Sucker Punch: Evolution of Arthropod Atypical Venom with a Neurotoxic Component in Robber Flies (Asilidae, Diptera) by Drukewitz, Stephan Holger, Fuhrmann, Nico, Undheim, Eivind A B, Blanke, Alexander, Giribaldi, Julien, Mary, Rosanna, Laconde, Guillaume, Dutertre, Sébastien, von Reumont, Björn Marcus

“…Predatory robber flies (Diptera, Asilidae) have been suspected to be venomous due to their ability to overpower well-defended prey. However, details of their…”
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Ecto-ATPase inhibition: ATP and adenosine release under physiological and ischemic in vivo conditions in the rat striatum by Melani, Alessia, Corti, Francesca, Stephan, Holger, Müller, Christa E., Donati, Chiara, Bruni, Paola, Vannucchi, Maria Giuliana, Pedata, Felicita

“…In the central nervous system (CNS) ATP and adenosine act as transmitters and neuromodulators on their own receptors but it is still unknown which part of…”
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Acute Effect of Electromyostimulation Superimposed on Running on Maximal Velocity, Metabolism, and Perceived Exertion by Stephan, Holger, Hagedorn, Thorsten, Wehmeier, Udo Frank, Tomschi, Fabian, Hilberg, Thomas

“…Electromyostimulation has been shown to intensify exercise when superimposed on cycling. However, little is known about the application during running, which…”
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Polyoxometalates—a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors by Müller, Christa E., Iqbal, Jamshed, Baqi, Younis, Zimmermann, Herbert, Röllich, Anita, Stephan, Holger

“…Polyoxotungstates were identified as novel potent inhibitors of ecto-NTPDases. [TiW 11CoO 40] 8− ( 7) exhibited a K i value of 140 nM at rat E-NTPDase1…”
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Additional Active Movements Are Not Required for Strength Gains in the Untrained during Short-Term Whole-Body Electromyostimulation Training by Stephan, Holger, Wehmeier, Udo Frank, Förster, Tim, Tomschi, Fabian, Hilberg, Thomas

“…Recommendations for conventional strength training are well described, and the volume of research on whole-body electromyostimulation training (WB-EMS) is…”
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Dual-Labelling Strategies for Nuclear and Fluorescence Molecular Imaging: Current Status and Future Perspectives by Kubeil, Manja, Martínez, Irma Ivette Santana, Bachmann, Michael, Kopka, Klaus, Tuck, Kellie L, Stephan, Holger

“…Molecular imaging offers the possibility to investigate biological and biochemical processes non-invasively and to obtain information on both anatomy and…”
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Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats by Bergmann, Ralf, Kubeil, Manja, Zarschler, Kristof, Chhabra, Sandeep, Tajhya, Rajeev B., Beeton, Christine, Pennington, Michael W., Bachmann, Michael, Norton, Raymond S., Stephan, Holger

“…The peptide HsTX1[R14A] is a potent and selective blocker of the voltage-gated potassium channel Kv1.3, which is a highly promising target for the treatment of…”
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Synthesis, Structural Characterization and Photodecarbonylation Study of a Dicarbonyl Ruthenium(II)‐Bisquinoline Complex by Kubeil, Manja, Joshi, Tanmaya, Wood, Bayden R., Stephan, Holger

“…A photoactivatable ruthenium(II) carbonyl complex mer,cis‐[Ru(II)Cl(BisQ)(CO)2]PF6 2 was prepared using a tridentate bisquinoline ligand…”
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Manufacturing capacity planning and the value of multi-stage stochastic programming under Markovian demand by Stephan, Holger A., Gschwind, Timo, Minner, Stefan

“…Capacity planning is a crucial part of global manufacturing strategies in the automotive industry, especially in the presence of volatile markets with high…”
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