Search Results - "Stepanović, Svetlana"
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Morphology versus DNA barcoding: two sides of the same coin. A case study of Ceutorhynchus erysimi and C. contractus identification
Published in Insect science (01-08-2016)“…Genotyping of 2 well-known weevil species from the genus Ceutorhynchus (Coleoptera: Curculionidae) distributed in west Palearctic, C. erysimi and C…”
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Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin
Published in The Journal of biological chemistry (27-03-2009)“…Sodium channels are fundamental signaling molecules in excitable cells, and are molecular targets for local anesthetic agents and intracellular free Ca2+…”
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Identification and Characterization of a Compound That Protects Cardiac Tissue from Human Ether-à-go-go-related Gene (hERG)-related Drug-induced Arrhythmias
Published in The Journal of biological chemistry (16-11-2012)“…The human Ether-à-go-go-related gene (hERG)-encoded K+ current, IKr is essential for cardiac repolarization but is also a source of cardiotoxicity because…”
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The evolutionarily conserved residue A653 plays a key role in HERG channel closing
Published in The Journal of physiology (01-06-2009)“…Human ether-a-go-go- related gene ( HERG ) encodes the rapid, outwardly rectifying K + current I Kr that is critical for repolarization of the cardiac action…”
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Genetic screening in C. elegans identifies rho-GTPase activating protein 6 as novel HERG regulator
Published in Journal of molecular and cellular cardiology (01-02-2009)“…Abstract The human ether-a-go-go related gene (HERG) constitutes the pore forming subunit of IKr , a K+ current involved in repolarization of the cardiac…”
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In vivo Identification of Genes That Modify Ether-a-Go-Go-Related Gene Activity in Caenorhabditis elegans May Also Affect Human Cardiac Arrhythmia
Published in Proceedings of the National Academy of Sciences - PNAS (10-08-2004)“…Human ether-a-go-go-related gene (HERG) encodes the pore-forming subunit of IKr, a cardiac K+channel. Although many commonly used drugs block IKr, in certain…”
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A calcium sensor in the sodium channel modulates cardiac excitability
Published in Nature (London) (24-01-2002)Get full text
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Extracellular sodium interacts with the HERG channel at an outer pore site
Published in The Journal of general physiology (01-10-2002)“…Most voltage-gated K(+) currents are relatively insensitive to extracellular Na(+) (Na(+)(o)), but Na(+)(o) potently inhibits outward human…”
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Functional interaction between extracellular sodium, potassium and inactivation gating in HERG channels
Published in The Journal of physiology (01-08-2004)“…We have studied the interaction between extracellular K + (K + o ) and extracellular Na + (Na + o ) in human ether-Ã -go-go related gene (HERG)-encoded K +…”
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Еколошка специјализација и генетичка диференцијација врста рода Ceutorhynchus (Curculionidae) према биљкама хранитељкама фамилије Brassicaceae
Published 01-01-2016“…Биологија и екологија врста рода Centorhyncћи није довольно позната нако су неке од врста значајне пољопривредне штеточине. У литератури се углавном наводе…”
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Dissertation -
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Nav1.5 C-Terminal Domains Influence Calcium Regulation of Fast Inactivation Separately from Calmodulin Interaction
Published in Biophysical journal (27-01-2015)Get full text
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A calcium sensor in the sodium channel modulates cardiac excitability
Published in Nature (London) (24-01-2002)“…Sodium channels are principal molecular determinants responsible for myocardial conduction and maintenance of the cardiac rhythm. Calcium ions (Ca2+) have a…”
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Mapping Residues that Influence Fast Inactivation Within Ca-Sensing Domains in the Nav1.5 C-Terminus
Published in Biophysical journal (01-02-2011)Get full text
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Variation in nuclear DNA content in Malus species and cultivated apples
Published in Genome (01-10-2005)“…The nuclear DNA content for a group of 40 Malus species and hybrids has been estimated using flow cytometry. Estimates of nuclear DNA content for this…”
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Mechanistic link between lidocaine block and inactivation probed by outer pore mutations in the rat μ1 skeletal muscle sodium channel
Published in The Journal of physiology (01-11-1998)“…1 Mutations that disrupt Na+ channel fast inactivation attenuate lidocaine (lignocaine)‐induced use dependence; however, the pharmacological role of slower…”
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Mechanistic link between lidocaine block and inactivation probed by outer pore mutations in the rat mu 1 skeletal muscle sodium channel
Published in The Journal of physiology (01-11-1998)“…* 1 Mutations that disrupt Na super(+) channel fast inactivation attenuate lidocaine (lignocaine)-induced use dependence; however, the pharmacological role of…”
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Journal Article -
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Mechanistic link between lidocaine block and inactivation probed by outer pore mutations in the rat μ1 skeletal muscle sodium channel
Published in The Journal of physiology (01-11-1998)“…Mutations that disrupt Na + channel fast inactivation attenuate lidocaine (lignocaine)-induced use dependence; however, the pharmacological role of slower…”
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Journal Article