Search Results - "Stepanov, Alexander A"
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Revelation of Proteomic Indicators for Colorectal Cancer in Initial Stages of Development
Published in Molecules (Basel, Switzerland) (31-01-2020)“…Colorectal cancer (CRC) at a current clinical level is still hardly diagnosed, especially with regard to nascent tumors, which are typically asymptotic…”
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2
Sports Nutrition: Diets, Selection Factors, Recommendations
Published in Nutrients (25-10-2021)“…An athlete's diet is influenced by external and internal factors that can reduce or exacerbate exercise-induced food intolerance/allergy symptoms. This review…”
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3
Diversity of Plant Sterols Metabolism: The Impact on Human Health, Sport, and Accumulation of Contaminating Sterols
Published in Nutrients (01-05-2021)“…The way of plant sterols transformation and their benefits for humans is still a question under the massive continuing revision. In fact, there are no…”
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4
Consolidation of metabolomic, proteomic, and GWAS data in connective model of schizophrenia
Published in Scientific reports (06-02-2023)“…Despite of multiple systematic studies of schizophrenia based on proteomics, metabolomics, and genome-wide significant loci, reconstruction of underlying…”
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5
Atomic Simulation of the Binding of JAK1 and JAK2 with the Selective Inhibitor Ruxolitinib
Published in International journal of molecular sciences (09-09-2022)“…Rheumatoid arthritis belongs to the group of chronic systemic autoimmune diseases characterized by the development of destructive synovitis and extra-articular…”
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In Silico Study of the Interactions of Anle138b Isomer, an Inhibitor of Amyloid Aggregation, with Partner Proteins
Published in International journal of molecular sciences (17-12-2022)“…Herein, we aimed to highlight current "gaps" in the understanding of the potential interactions between the Anle138b isomer ligand, a promising agent for…”
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3β-Corner Stability by Comparative Molecular Dynamics Simulations
Published in International journal of molecular sciences (02-10-2022)“…This study explored the mechanisms by which the stability of super-secondary structures of the 3β-corner type autonomously outside the protein globule are…”
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Optical Configuration Effect on the Structure and Reactivity of Diastereomers Revealed by Spin Effects and Molecular Dynamics Calculations
Published in International journal of molecular sciences (21-12-2021)“…The peculiarities of spin effects in photoinduced electron transfer (ET) in diastereomers of donor-acceptor dyads are considered in order to study the…”
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Mass Spectrometric Identification of Proteins Enhanced by the Atomic Force Microscopy Immobilization Surface
Published in International journal of molecular sciences (04-01-2021)“…An approach to highly-sensitive mass spectrometry detection of proteins after surface-enhanced concentrating has been elaborated. The approach is based on a…”
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10
Role of Chiral Configuration in the Photoinduced Interaction of D- and L-Tryptophan with Optical Isomers of Ketoprofen in Linked Systems
Published in International journal of molecular sciences (08-06-2021)“…The study of the L- and D-amino acid properties in proteins and peptides has attracted considerable attention in recent years, as the replacement of even one…”
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Stereoselectivity of Electron and Energy Transfer in the Quenching of ( S / R )-Ketoprofen-( S )-Tryptophan Dyad Excited State
Published in International journal of molecular sciences (28-07-2020)“…Photoinduced elementary processes in chiral linked systems, consisting of drugs and tryptophan (Trp) residues, attract considerable attention due to several…”
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Pharmacogenetic Testing: A Tool for Personalized Drug Therapy Optimization
Published in Pharmaceutics (19-12-2020)“…Pharmacogenomics is a study of how the genome background is associated with drug resistance and how therapy strategy can be modified for a certain person to…”
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13
Chromatomass-Spectrometric Method for the Quantitative Determination of Amino- and Carboxylic Acids in Biological Samples
Published in Metabolites (22-12-2022)“…A highly sensitive method for the qualitative and quantitative determination of amino- and carboxylic acids, as well as a number of urea and methionine cycle…”
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Determination of Heterogeneous Proteomic and Metabolomic Response in anti-TNF and anti-IL-6 Treatment of Patients with Rheumatoid Arthritis
Published in Life (Basel, Switzerland) (01-02-2023)“…Reduction in tumor necrosis factor (αTNF) and interleukin-6 (IL-6) activities is a widely utilized strategy for the treatment of rheumatoid arthritis (RA) with…”
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15
Proteomic and Metabolomic Analyses of the Blood Samples of Highly Trained Athletes
Published in Data (Basel) (01-01-2024)“…High exercise loading causes intricate and ambiguous proteomic and metabolic changes. This study aims to describe the dataset on protein and metabolite…”
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Metabolomic and Proteomic Profiling of Athletes Performing Physical Activity under Hypoxic Conditions
Published in Sports (Basel) (01-03-2024)“…Proteomic and metabolomic research enables quantitation of the molecular profile of athletes. Multiomic profiling was conducted using plasma samples collected…”
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Circulating IgG Fragments for Gastric Cancer and Esophageal Cancer
Published in Diagnostics (Basel) (30-06-2024)“…Blood serum of patients with gastric ( = 68) and esophageal ( = 43) cancer was assessed for proteolytic fragments of IgG. Serum samples of 20 healthy donors…”
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Molecular Profiling of Athletes Performing High-Intensity Exercises in Extreme Environments
Published in Sports (Basel) (01-02-2023)“…The aim of this study was to determine the influence of high-intensity training under extreme conditions (T = 40 °C) on the metabolism and immunological…”
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Influence of Sports Training in Foothills on the Professional Athlete's Immunity
Published in Sports (Basel) (30-01-2023)“…Neuroplasticity and inflammation play important part in the body's adaptive reactions in response to prolonged physical activity. These processes are…”
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Pilot Study of the Metabolomic Profile of an Athlete after Short-Term Physical Activity
Published in Data (Basel) (01-01-2023)“…A comprehensive analysis of indicators of the state of the body between training and recovery allows a comprehensive evaluation of various aspects of health,…”
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