Search Results - "Stepanichev, M Yu"

Molecular and cellular mechanisms of sporadic Alzheimer’s disease: Studies on rodent models in vivo by Gulyaeva, N. V., Bobkova, N. V., Kolosova, N. G., Samokhin, A. N., Stepanichev, M. Yu, Stefanova, N. A.

“…In this review, recent data are presented on molecular and cellular mechanisms of pathogenesis of the most widespread (about 95%) sporadic forms of Alzheimer’s…”
Get full text

Long-term potentiation in the hippocampal CA3 to CA1 synapses may be induced in vivo by activation of septal cholinergic inputs by Dobryakova, Y. V., Stepanichev, M. Yu, Markevich, V. A., Bolshakov, A. P.

“…The role of cholinergic neurotransmission in the hippocampus remains controversial since different studies showed either no influence or its modulatory effect…”
Get full text

Neonatal Proinflammatory Stress and the Maturation of Intercellular Communication in the Hippocampus by Kudryashova, I. V., Stepanichev, M. Yu, Gulyaeva, N. V.

“…Neuroinflammatory processes, particularly those induced by infectious agents, are associated with activation of the microglia and subsequent increases in the…”
Get full text

Impaired Memory Formation and the Development of Transient Cholinergic Deficit in Mice after Olfactory Bulbectomy by Nedogreeva, O. A., Lazareva, N. A., Stepanichev, M. Yu, Gulyaeva, N. V.

“…Olfactory bulbectomy in rodents is widely used as a model of the symptoms of clinical depression and neurodegeneration, including cholinergic. Male C57BL/6…”
Get full text

Behavior of Rats in a Forced Swimming Test Is Not an Unambiguous Predictor for the Development of Anhedonia in Chronic Stress by Manolova, A. O., Stepanichev, M. Yu, Gulyaeva, N. V.

“…Anhedonia is one of the central features of the development of depression. Chronic stress leads to the development of depression-like behavior in experimental…”
Get full text

Neonatal proinflammatory stress induces accumulation of corticosterone and interleukin-6 in the hippocampus of juvenile rats: Potential mechanism of synaptic plasticity impairments by Onufriev, M. V., Freiman, S. V., Peregud, D. I., Kudryashova, I. V., Tishkina, A. O., Stepanichev, M. Yu, Gulyaeva, N. V.

“…Infectious diseases in early postnatal ontogenesis can induce neuroinflammation, disrupt normal central nervous system development, and contribute to…”
Get full text

Chronic Stress Induced by Keeping in Conditions of Nesting Material Deficiency in the Early Postnatal Period Affects Behavior and Stress Reactivity in Male Rats by Stepanichev, M. Yu, Nedogreeva, O. A., Klimanova, M. A., Moiseeva, Yu. V., Onufriev, M. V., Lazareva, N. A., Gulyaeva, N. V.

“…Rodent models of deprivation of parental care are increasingly used to model depression-like disorders induced by early stress. The present study used a model…”
Get full text

Studies of the effects of fragment (25-35) of beta-amyloid peptide on the behavior of rats in a radial maze by Stepanichev, M Yu, Moiseeva, Yu V, Lazareva, N A, Gulyaeva, N V

“…Decreases in cognitive functions, particularly long-term (episodic) and working memory, are among the earliest prognostic signs of Alzheimer's disease. The…”
Get full text

Pentylenetetrazol kindling in rats: Is neurodegeneration associated with manifestations of convulsive activity? by Pavlova, T V, Yakovlev, A A, Stepanichev, M Yu, Gulyaeva, N V

“…Structural changes in neurons and measures of oxidative stress were studied in the hippocampus of rats tolerant (ST) and sensitive (SS) to developing…”
Get full text

The Acute Post-Traumatic Period in Rats Is Accompanied by an Anxiety State and a Decrease in the Proportion of REM Sleep by Komol’tsev, I. G., Levshina, I. P., Novikova, M. R., Tishkina, A. O., Stepanichev, M. Yu, Gulyaeva, N. V.

“…The sequelae of craniocerebral trauma (CCT) were studied using a model based on severe (3–4 atm) lateral hydrodynamic percussion (liquid-percussive brain…”
Get full text

The Dorsal and Ventral Hippocampus Have Different Reactivities to Proinflammatory Stress: Corticosterone Levels, Cytokine Expression, and Synaptic Plasticity by Onufriev, M. V., Uzakov, Sh. S., Freiman, S. V., Stepanichev, M. Yu, Moiseeva, Yu. V., Lazareva, N. A., Markevich, V. A., Gulyaeva, N. V.

“…The dorsal and ventral parts of the hippocampus are functionally and morphologically nonidentical, and differences include stress reactivity. The present…”
Get full text

Electroconvulsive shock induces neuron death in the mouse hippocampus: correlation of neurodegeneration with convulsive activity by Zarubenko, I I, Yakovlev, A A, Stepanichev, M Yu, Gulyaeva, N V

“…The relationship between convulsive activity evoked by repeated electric shocks and structural changes in the hippocampus of Balb/C mice was studied. Brains…”
Get full text

Chronic Mild Stress Increases the Expression of Genes Encoding Proinflammatory Cytokines in the Rat Brain by Stepanichev, M. Yu, Peregud, D. I., Manolova, A. O., Lazareva, N. A., Onufriev, M. V., Gulyaeva, N. V.

“…Alterations in the expression of genes encoding interleukins IL-1α, IL-1β, IL-6, and tumor necrosis factor-α (TNF-α) were studied in the rat brain in a model…”
Get full text

Effects of Single Injections of Brain-Derived Neurotrophic Factors into the Midline Ventral Tegmental Area on the Reinforcing Properties of Morphine by Peregud, D. I., Stepanichev, M. Yu, Lazareva, N. A., Panchenko, L. F., Gulyaeva, N. V.

“…The strong positive reinforcing effect of opiates is regarded as a trigger for the development of pathological dependence, though the neurobiological basis of…”
Get full text

Changes in the Cerebral Cortex after Dosed Craniocerebral Trauma in Rats of Different Ages by Komol’tsev, I. G., Levshina, I. P., Novikova, M. R., Stepanichev, M. Yu, Tishkina, A. O., Gulyaeva, N. V.

“…Dosed lateral fluid percussion was used to model craniocerebral trauma (CCT) of moderate to severe intensity in one- and two-year-old rats. Brain sections were…”
Get full text

An early decrease in cell proliferation after pentylenetetrazole-induced seizures by Aniol, V.A, Stepanichev, M.Yu, Lazareva, N.A, Gulyaeva, N.V

“…Abstract There are increasing data on the influence of seizures on neurogenesis in the adult brain. However, data on cell proliferation and differentiation…”
Get full text

Effect of a Single Injection of Brain Derived Neurotrophic Factor into Midline Ventral Tegmental Area on Morphine Reinforcing Properties by Peregud, D I, Stepanichev, M Yu, Lazareva, N A, Panchenko, L F, Gulyaeva, N V

“…Opiate reinforcement is considered as a stimulus inducing addiction, however underlying neurobiological mechanisms remain obscure. According to the literature,…”
Get more information

Single intracerebroventricular administration of amyloid-beta (25–35) peptide induces impairment in short-term rather than long-term memory in rats by Stepanichev, M.Yu, Moiseeva, Yu.V, Lazareva, N.A, Onufriev, M.V, Gulyaeva, N.V

“…Ample experimental evidence indicates that intracerebral injection or infusion of amyloid-beta peptides (Aβ) to rodents induces learning and memory impairments…”
Get full text

The Effects of Chronic Combined Stress: Changes in Behavior of Rats with Various Responses to Novelty by Stepanichev, M Yu, Tishkina, A O, Novikova, M R, Levshina, I P, Piskunov, A K, Lazareva, N A, Gulyaeva, N V

“…We studied the effect of chronic combined stress (model of experimental neurosis) on behavior of rats with different basal strategies of behavior in novelty…”
Get more information

Neurodegenerative Changes in Rat Hippocampal Fields during the Development of Pentylenetetrazole Kindling by Popova, M. S., Aniol, V. A., Lazareva, N. A., Stepanichev, M. Yu, Gulyaeva, N. V.

“…The development of pentylenetetrazole kindling is accompanied by neuron degeneration and death in different hippocampal fields. Nonetheless, data on the…”
Get full text