Search Results - "Stepan, Lara P."

Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors by Meininger, David, Zalameda, Leeanne, Liu, Yichin, Stepan, Lara P., Borges, Luis, McCarter, John D., Sutherland, Claire L.

“…Indoleamine 2,3-dioxygenase (IDO1) catalyzes the first step in tryptophan breakdown along the kynurenine pathway. Therapeutic inhibition of IDO1 is receiving…”
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Expression of Trop2 Cell Surface Glycoprotein in Normal and Tumor Tissues: Potential Implications as a Cancer Therapeutic Target by Stepan, Lara P., Trueblood, Esther S., Hale, Kari, Babcook, John, Borges, Luis, Sutherland, Claire L.

“…Trop2 is a cell-surface glycoprotein reported to be overexpressed in various types of adenocarcinomas with minimal expression in normal tissues. Recent…”
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Specific stimulation of MHC-transgenic mouse T-cell hybridomas with xenogeneic APC by Vidovic, Damir, Graddis, Thomas J, Stepan, Lara P, Zaller, Dennis M, Laus, Reiner

“…From the recombinant human leukocyte antigen (HLA)-DR1/H2-E k major histocompatibility complex (MHC) class II–transgenic mice, we have generated two CD4 +…”
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