Search Results - "Stenzel, KH"

Interleukin-6 predicts hypoalbuminemia, hypocholesterolemia, and mortality in hemodialysis patients by Bologa, RM, Levine, DM, Parker, TS, Cheigh, JS, Serur, D, Stenzel, KH, Rubin, AL

“…Low serum albumin and low serum cholesterol levels are among the most consistent predictors of mortality in patients with end-stage renal disease (ESRD)…”
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Poly[allylamine hydrochloride] (RenaGel): a noncalcemic phosphate binder for the treatment of hyperphosphatemia in chronic renal failure by Chertow, G M, Burke, S K, Lazarus, J M, Stenzel, K H, Wombolt, D, Goldberg, D, Bonventre, J V, Slatopolsky, E

“…Dietary phosphate restriction and the oral administration of calcium and aluminum salts have been the principal means of controlling hyperphosphatemia in…”
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Selective effects of TPA and IL-1 on protein phosphorylation in murine thymocytes by Avissar, S, Stenzel, K H, Novogrodsky, A

“…Protein kinase C activity was demonstrated in murine thymocytes and the effects of TPA and IL-1 on this enzyme were studied. TPA, but not IL-1, could…”
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Neutralization of Endotoxin by a Phospholipid Emulsion in Healthy Volunteers by Gordon, Bruce R., Parker, Thomas S., Levine, Daniel M., Feuerbach, Fred, Saal, Stuart D., Sloan, Betty-Jane, Chu, Cindy, Stenzel, Kurt H., Parrillo, Joseph E., Rubin, Albert L.

“…BackgroundAn approach to endotoxin (lipopolysaccharide [LPS]) blockade makes use of the ability of lipoproteins, via surface phospholipids, to bind and…”
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Regulation of new DNA synthesis in mammalian cells by cyclosporine. Demonstration of a transforming growth factor beta-dependent mechanism of inhibition of cell growth by Khanna, A, Li, B, Stenzel, K H, Suthanthiran, M

“…Immunosuppressants such as cyclosporine are considered to constrain cell growth by preventing the production of growth stimulatory cytokines (e.g.,…”
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Differential regulation of transforming growth factor β and interleukin 2 genes in human T cells : demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction by LI, B, SEHAJPAL, P. K, KHANNA, A, VLASSARA, H, CERAMI, A, STENZEL, K. H, SUTHANTHIRAN, M

“…The regulation of mRNA encoding transforming growth factor beta (TGF-beta) and interleukin 2 (IL-2) in normal human T cells was explored using novel competitor…”
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Hypertension is not adequately controlled in hemodialysis patients by Cheigh, J S, Milite, C, Sullivan, J F, Rubin, A L, Stenzel, K H

“…To examine the adequacy of hypertension control, we monitored the blood pressure (BP) of 53 hemodialysis patients who received treatment for hypertension. BP…”
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Safety and Pharmacokinetics of an Endotoxin-Binding Phospholipid Emulsion by Gordon, Bruce R, Parker, Thomas S, Levine, Daniel M, Saal, Stuart D, Hudgins, Lisa Cooper, Sloan, Betty-Jane, Chu, Cindy, Stenzel, Kurt H, Rubin, Albert L

“…BACKGROUND: Lipids and lipoproteins have been shown to bind and neutralize endotoxin and to improve outcomes in animal models of sepsis. OBJECTIVE: To provide…”
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End-stage renal disease in systemic lupus erythematosus by Cheigh, J S, Stenzel, K H

“…The progression of lupus nephritis severe enough to require dialysis does not necessarily indicate that it is "end-stage." Ten percent to 28% of patients with…”
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Intragraft expression of IL-10 messenger RNA: A novel correlate of renal allograft rejection by Xu, Guo-Ping, Sharma, Vijay K., Li, Baogui, Bologa, Roxana, Li, Yi, Mouradian, Janet, Wang, John, Serur, David, Rao, Venkateswara, Stenzel, Kurt H., Suthanthiran, Manikkam

“…Intragraft expression of IL-10 messenger RNA: A novel correlate of renal allograft rejection. A major conceptual advance is the formulation that type I…”
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Immune stimulatory properties of metalloporphyrins by Novogrodsky, A, Suthanthiran, M, Stenzel, KH

“…A possible approach to the immunotherapy of tumors is to stimulate either specific or nonspecific immune responses in vivo. We recently found that provision of…”
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Synergism between the CD3 antigen- and CD2 antigen-derived signals. Exploration at the level of induction of DNA-binding proteins and characterization of the inhibitory activity of cyclosporine by Sehajpal, P K, Sharma, V K, Ingulli, E, Stenzel, K H, Suthanthiran, M

“…We have demonstrated earlier that the crosslinkage of the CD3/TCR complex with the CD2 antigen results in the proliferation of normal human T cells. The effect…”
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Effect of polar organic compounds on leukemic cells. Butyrate-induced partial remission of acute myelogenous leukemia in a child by Novogrodsky, A, Dvir, A, Ravid, A, Shkolnik, T, Stenzel, K H, Rubin, A L, Zaizov, R

“…Polar organic compounds, such as dimethylsulfoxide and butyric acid, are known to induce differentiation in Friend erythroleukemia cells as well as in other…”
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Immune stimulatory and anti‐tumour properties of haemin by TSUJI, A., WANG, J., STENZEL, K. H., NOVOGRODSKY, A.

“…SUMMARY IL‐2 induces tumour regression in some patients with metastatic disease, but the dose of IL‐2 is limited by severe toxicity. Agents that increase the…”
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Immunotherapy with Anti-CD3 Monoclonal Antibodies and Recombinant Interleukin 2: Stimulation of Molecular Programs of Cytotoxic Killer Cells and Induction of Tumor Regression by Nakajima, Fumio, Khanna, Ashwani, Xu, Guoping, Lagman, Mila, Haschemeyer, Rudy, Mouradian, Janet, Wang, John C., Stenzel, Kurt H., Rubin, Albert L., Suthanthiran, Manikkam

“…Adoptive cellular immunotherapy, infusions of interleukin 2 (IL-2) in conjunction with in vitro-activated killer cells, has brought new hope to patients with…”
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Hypertension in kidney transplant recipients. Effect on long-term renal allograft survival by Cheigh, J S, Haschemeyer, R H, Wang, J C, Riggio, R R, Tapia, L, Stenzel, K H, Rubin, A L

“…To examine the effects of hypertension on renal graft function, we studied the clinical course of 144 kidney transplant recipients who had functioning grafts…”
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Excellent outcome with a calcium channel blocker-supplemented immunosuppressive regimen in cadaveric renal transplantation. A potential strategy to avoid antibody induction protocols by Suthanthiran, M, Haschemeyer, R H, Riggio, R R, Adubor, C, Friedman, G S, Cheigh, J S, Wang, J C, Fotino, M, Stubenbord, W T, Saal, S D

“…Many transplant centers routinely utilize monoclonal antibody or polyclonal antibody based induction protocols in recipients of cadaver renal allografts. Given…”
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Hydroxyl radical scavengers inhibit human natural killer cell activity by Suthanthiran, M, Solomon, S D, Williams, P S, Rubin, A L, Novogrodsky, A, Stenzel, K H

“…As natural killer (NK) cell activity is an essential constituent of host defence systems and reactive oxygen intermediates participate in such defence, the…”
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OKT3-associated adverse reactions: mechanistic basis and therapeutic options by Suthanthiran, M, Fotino, M, Riggio, R R, Cheigh, J S, Stenzel, K H

“…OKT3, a prototypic monoclonal antibody directed at the lineage-specific CD3 antigen expressed on mature T cells, is an effective immunosuppressant in organ…”
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Impact of renal donation. Long-term clinical and biochemical follow-up of living donors in a single center by Miller, I J, Suthanthiran, M, Riggio, R R, Williams, J J, Riehle, R A, Vaughan, E D, Stubenbord, W T, Mouradian, J, Cheigh, J S, Stenzel, K H

“…Forty-six renal donors who responded to a questionnaire and two additional donors with nephrotic syndrome and renal insufficiency were studied. The mean age…”
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