Search Results - "Stenning, SP"

A Medical Research Council trial of two radiotherapy doses in the treatment of grades 3 and 4 astrocytoma by BLEEHEN, N. M, STENNING, S. P

Get full text

Chemotherapy in adult high-grade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials by Stewart, L A

“…Trials on the effect of systemic chemotherapy on survival and recurrence in adults with high-grade glioma have had inconclusive results. We undertook a…”
Get full text

Radiotherapy versus single-dose carboplatin in adjuvant treatment of stage I seminoma: a randomised trial by Oliver, RTD, Mason, MD, Mead, GM, von der Maase, H, Rustin, GJS, Joffe, JK, de Wit, R, Aass, N, Graham, JD, Coleman, R, Kirk, SJ, Stenning, SP

“…Adjuvant radiotherapy is effective treatment for stage I seminoma, but is associated with a risk of late non-germ-cell cancer and cardiovascular events. After…”
Get full text

Randomized Trial of 30 Versus 20 Gy in the Adjuvant Treatment of Stage I Testicular Seminoma: A Report on Medical Research Council Trial TE18, European Organisation for the Research and Treatment of Cancer Trial 30942 (ISRCTN18525328) by JONES, William G, FOSSA, Sophie D, MEAD, Graham M, ROBERTS, J. Trevor, SOKAL, Michael, HORWICH, Alan, STENNING, Sally P

“…To assess the possibility of reducing radiotherapy doses without compromising efficacy in the management of patients with stage I seminoma. Patients were…”
Get full text

DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular study by Barratt, PL, Seymour, MT, Stenning, SP, Georgiades, I, Walker, C, Birbeck, K, Quirke, P

“…Present clinical algorithms assign adjuvant chemotherapy according to prognosis, but clinical decisionmaking would be greatly improved if reliable predictive…”
Get full text

An international evaluation of CODOX-M and CODOX-M alternating with IVAC in adult Burkitt’s lymphoma: results of United Kingdom Lymphoma Group LY06 study by Mead, G. M., Sydes, M. R., Walewski, J., Grigg, A., Hatton, C. S., Norbert, P., Guarnaccia, C., Lewis, M. S., McKendrick, J., Stenning, S. P., Wright, D.

“…Background: Burkitt’s lymphoma (BL) is a rare and rapidly progressive form of B-cell non-Hodgkin’s lymphoma. Cyclophosphamide, vincristine, doxorubicin,…”
Get full text

A phase II trial of TIP (paclitaxel, ifosfamide and cisplatin) given as second-line (post-BEP) salvage chemotherapy for patients with metastatic germ cell cancer: a medical research council trial by MEAD, G. M, CULLEN, M. H, HUDDART, R, HARPER, P, RUSTIN, G. J. S, COOK, P. A, STENNING, S. P, MASON, M

“…This phase II trial describes the use of TIP chemotherapy (paclitaxel, ifosfamide and cisplatin) as salvage for patients with metastatic germ cell cancer (GCC)…”
Get full text

Comparison of ABVD and Alternating or Hybrid Multidrug Regimens for the Treatment of Advanced Hodgkin's Lymphoma: Results of the United Kingdom Lymphoma Group LY09 Trial (ISRCTN97144519) by JOHNSON, Peter W. M, RADFORD, John A, RYDER, David, HANCOCK, Barry W, CULLEN, Michael H, SYDES, Matthew R, WALEWSKI, Jan, JACK, Andrew S, MACLENNAN, Kenneth A, STENNING, Sally P, CLAWSON, Simon, SMITH, Paul

“…To perform an open-label, randomized, controlled trial comparing treatment with doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) with two multidrug…”
Get full text

Optimal Planning Target Volume for Stage I Testicular Seminoma: A Medical Research Council Randomized Trial by FOSSA, S. D, HORWICH, A, GROSCH, E. J, CHETIYAWARDANA, A. D, REED, N. S, WIDMER, B, RUSSELL, J. M, ROBERTS, J. T, CULLEN, M. H, HODSON, N. J, JONES, W. G, YOSEF, H, DUCHESNE, G. M, OWEN, J. R

“…PURPOSE: To compare relapse rates and toxicity associated with para-aortic (PA) strip or PA and ipsilateral iliac lymph node irradiation (dogleg [DL] field)…”
Get full text

Impact of the Treating Institution on Survival of Patients With“Poor-Prognosis” Metastatic Nonseminoma by Collette, Laurence, Sylvester, Richard J., Stenning, Sally P., Fossa, Sophie D., Mead, Graham M., de Wit, Ronald, de Mulder, Pieter H. M., Neymark, Niels, Lallemand, Eric, Kaye, Stanley B.

“…BACKGROUND: Because metastatic nonseminomatous germ cell cancer is a rare but treatable cancer, we have explored whether there is an association between the…”
Get full text

Mathematical Modelling of Survival of Glioblastoma Patients Suggests a Role for Radiotherapy Dose Escalation and Predicts Poorer Outcome After Delay to Start Treatment by Burnet, N.G., Jena, R., Jefferies, S.J., Stenning, S.P., Kirkby, N.F.

“…The outcome of patients with glioblastoma (GBM) remains extremely poor. We have developed a mathematical model, using pathological and radiation biology…”
Get full text

Randomized trial of bleomycin, etoposide, and cisplatin compared with bleomycin, etoposide, and carboplatin in good-prognosis metastatic nonseminomatous germ cell cancer: a Multiinstitutional Medical Research Council/European Organization for Research and Treatment of Cancer Trial by Horwich, A, Sleijfer, D T, Fosså, S D, Kaye, S B, Oliver, R T, Cullen, M H, Mead, G M, de Wit, R, de Mulder, P H, Dearnaley, D P, Cook, P A, Sylvester, R J, Stenning, S P

“…This prospective randomized multicenter trial was designed to evaluate the efficacy of carboplatin plus etoposide and bleomycin (CEB) versus cisplatin plus…”
Get more information

Adjuvant bleomycin, vincristine and cisplatin (BOP) for high-risk stage I non-seminomatous germ cell tumours: a prospective trial (MRC TE17) by DEARNALEY, D. P, FOSSA, S. D, COOK, P. A, STENNING, S. P, KAYE, S. B, CULLEN, M. H, HARLAND, S. J, SOKAL, M. P. J, GRAHAM, J. D, ROBERTS, J. T, MEAD, G. M, WILLIAMS, M. V

“…Adjuvant BEP (bleomycin, etoposide, cisplatin) is effective treatment for high-risk clinical stage I (HRCS1) non-seminomatous germ cell tumours (NSGCT), but…”
Get full text

Short-course adjuvant chemotherapy in high-risk stage I nonseminomatous germ cell tumors of the testis: a Medical Research Council report by Cullen, M H, Stenning, S P, Parkinson, M C, Fossa, S D, Kaye, S B, Horwich, A H, Harland, S J, Williams, M V, Jakes, R

“…This United Kingdom Medical Research Council (UK-MRC) study prospectively evaluated efficacy and long-term toxicity of adjuvant chemotherapy in high-risk stage…”
Get more information

Hypofractionated radiotherapy for poor prognosis malignant glioma: matched pair survival analysis with MRC controls by McAleese, J.J, Stenning, S.P, Ashley, S, Traish, D, Hines, F, Sardell, S, Guerrero, D, Brada, Michael

“…Purpose: To assess the survival benefit of palliative hypofractionated radiotherapy in patients with poor prognosis high grade glioma by a matched comparison…”
Get full text

A Medical Research Council randomized trial of single agent carboplatin versus etoposide and cisplatin for advanced metastatic seminoma by HORWICH, A, OLIVER, R. T. D, STENNING, S. P, WILKINSON, P. M, MEAD, G. M, HARLAND, S. J, CULLEN, M. H, ROBERTS, J. T, FOSSA, S. D, DEARNALEY, D. P, LALLEMAND, E

“…The UK Medical Research Council conducted this trial of carboplatin chemotherapy in advanced seminoma to compare single agent carboplatin with a standard…”
Get full text

Prognostic factors in patients progressing after cisplatin-based chemotherapy for malignant non-seminomatous germ cell tumours by FOSS, S. D, STENNING, S. P, MEAD, G. M, CULLEN, M. H, KAYE, S. B, RUSTIN, G. J. S, COOK, P. A, GERL, A, HORWICH, A, CLARK, P. I, WILKINSON, P. M, JONES, W. G, WILLIAMS, M. V, OLIVER, R. T, NEWLANDS, E. S

“…The aim of this study was to define prognostic parameters for survival in patients with malignant germ cell tumours progressing after platinum-based induction…”
Get full text

Survival of patients with nonseminomatous germ cell cancer: a review of the IGCC classification by Cox regression and recursive partitioning by VAN DIJK, M. R, STEYERBERG, E. W, STENNING, S. P, DUSSELDORP, E, HABBEMA, J. D. F

“…The International Germ Cell Consensus (IGCC) classification identifies good, intermediate and poor prognosis groups among patients with metastatic…”
Get full text

Intratubular germ cell neoplasia of the contralateral testis in testicular cancer: defining a high risk group by Harland, S J, Cook, P A, Fossa, S D, Horwich, A, Mead, G M, Parkinson, M C, Roberts, J T, Stenning, S P

“…We define a group of testis cancer patients who are at high risk for carcinoma in situ of the contralateral testis and, therefore, a second germ cell tumor…”
Get more information

Radiotherapy for malignant gliomas in the elderly by Brada, Michael, Stenning, Sally Patricia

“…While fractionated external beam radiotherapy remains the principal treatment in patients with histologically verified malignant glioma, its use in older…”
Get full text