Search Results - "Stenman, Lotta K"

A novel mechanism for gut barrier dysfunction by dietary fat: epithelial disruption by hydrophobic bile acids by Stenman, Lotta K, Holma, Reetta, Eggert, Ariane, Korpela, Riitta

“…Impairment of gut barrier is associated with a fat-rich diet, but mechanisms are unknown. We have earlier shown that dietary fat modifies fecal bile acids in…”
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High-fat-induced intestinal permeability dysfunction associated with altered fecal bile acids by Stenman, Lotta K, Holma, Reetta, Korpela, Riitta

“…AIM： To investigate whether high-fat-feeding is associ- ated with increased intestinal permeability via altera- tions in bile acid metabolism. METHODS： Male…”
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Strain specific stress-modulating effects of candidate probiotics: A systematic screening in a mouse model of chronic restraint stress by Stenman, Lotta K., Patterson, Elaine, Meunier, Johann, Roman, Francois J., Lehtinen, Markus J.

“…•The impact of probiotics on gut-brain-axis signaling is species- and strain-specific.•Chronic restraint is a suitable model for detecting efficacy of…”
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Polydextrose with and without Bifidobacterium animalis ssp. lactis 420 drives the prevalence of Akkermansia and improves liver health in a multi-compartmental obesogenic mice study by Yde, Christian Clement, Jensen, Henrik Max, Christensen, Niels, Servant, Florence, Lelouvier, Benjamin, Lahtinen, Sampo, Stenman, Lotta K, Airaksinen, Kaisa, Kailanto, Henna-Maria

“…The past two decades of research have raised gut microbiota composition as a contributing factor to the development of obesity, and higher abundance of certain…”
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Chronic kidney disease stage is associated with the number of risk factors in type 2 diabetes patients (STages Of NEphropathy in type 2 diabetes and Heart Failure - STONE HF) by Metsärinne, Kaj, Pietilä, Mikko, Kantola, Ilkka, K Stenman, Lotta, Vesikansa, Aino, Ruokolainen, Lasse, Niskanen, Leo

“…To study the association between risk factors and chronic kidney disease (CKD), and characterize medication use in Finnish primary care type 2 diabetes (T2D)…”
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Probiotic With or Without Fiber Controls Body Fat Mass, Associated With Serum Zonulin, in Overweight and Obese Adults—Randomized Controlled Trial by Stenman, Lotta K., Lehtinen, Markus J., Meland, Nils, Christensen, Jeffrey E., Yeung, Nicolas, Saarinen, Markku T., Courtney, Michael, Burcelin, Rémy, Lähdeaho, Marja-Leena, Linros, Jüri, Apter, Dan, Scheinin, Mika, Kloster Smerud, Hilde, Rissanen, Aila, Lahtinen, Sampo

“…The gut microbiota is interlinked with obesity, but direct evidence of effects of its modulation on body fat mass is still scarce. We investigated the possible…”
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Genetically obese mice do not show increased gut permeability or faecal bile acid hydrophobicity by Stenman, Lotta K., Holma, Reetta, Gylling, Helena, Korpela, Riitta

“…Gut barrier dysfunction may lead to metabolic endotoxaemia and low-grade inflammation. Recent publications have demonstrated gut barrier dysfunction in obesity…”
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Higher fecal bile acid hydrophobicity is associated with exacerbation of dextran sodium sulfate colitis in mice by Stenman, Lotta K, Holma, Reetta, Forsgård, Richard, Gylling, Helena, Korpela, Riitta

“…Increased luminal bile acid hydrophobicity is associated with cytotoxicity and has been suggested to contribute to gut barrier dysfunction. The aim of this…”
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The majority of type 2 diabetic patients in Finnish primary care are at very high risk of cardiovascular events: A cross-sectional chart review study (STONE HF) by Metsärinne, Kaj, Pietilä, Mikko, Kantola, Ilkka, Stenman, Lotta K., Hätinen, Olli-Pekka, Vesikansa, Aino, Poussa, Tuija, Niskanen, Leo

“…•Over 60% of primary care T2D patients were at very high risk of cardiovascular events.•DKD was underdiagnosed even when eGFR and albuminuria were…”
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Probiotic B420 and prebiotic polydextrose improve efficacy of antidiabetic drugs in mice by Stenman, Lotta K, Waget, Aurélie, Garret, Céline, Briand, François, Burcelin, Rémy, Sulpice, Thierry, Lahtinen, Sampo

“…Gut microbiota is now known to control glucose metabolism. Previous studies have shown that probiotics and prebiotics may improve glucose metabolism, but their…”
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