Search Results - "Stengård, J"

DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene by Nickerson, Deborah A, Taylor, Scott L, Weiss, Kenneth M, Clark, Andrew G, Hutchinson, Richard G, Stengård, Jari, Salomaa, Veikko, Vartiainen, Erkki, Boerwinkle, Eric, Sing, Charles F

“…Lipoprotein lipase plays a central role in lipid metabolism and the gene that encodes this enzyme (LPL) is a candidate susceptibility gene for cardiovascular…”
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Haplotype Structure and Population Genetic Inferences from Nucleotide-Sequence Variation in Human Lipoprotein Lipase by Clark, Andrew G., Weiss, Kenneth M., Nickerson, Deborah A., Taylor, Scott L., Buchanan, Anne, Stengård, Jari, Salomaa, Veikko, Vartiainen, Erkki, Perola, Markus, Boerwinkle, Eric, Sing, Charles F.

“…Allelic variation in 9.7 kb of genomic DNA sequence from the human lipoprotein lipase gene ( LPL) was scored in 71 healthy individuals (142 chromosomes) from…”
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Dietary factors determining diabetes and impaired glucose tolerance. A 20-year follow-up of the Finnish and Dutch cohorts of the Seven Countries Study by FESKENS, E. J. M, VIRTANEN, S. M, RÄSÄNEN, L, TUOMILEHTO, J, STENGARD, J, PEKKANEN, J, NISSINEN, A, KROMHOUT, D

“…Dietary factors determining diabetes and impaired glucose tolerance. A 20-year follow-up of the Finnish and Dutch cohorts of the Seven Countries Study. E J…”
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Genotyping of human cytochrome P450 2A6 (CYP2A6), a nicotine C-oxidase by Oscarson, Mikael, Gullstén, Harriet, Rautio, Arja, Bernal, Maria Luisa, Sinues, Blanca, Dahl, Marja-Liisa, Stengård, Jari H, Pelkonen, Olavi, Raunio, Hannu, Ingelman-Sundberg, Magnus

“…Cytochrome P450 2A6 (CYP2A6) is a polymorphic enzyme responsible for the oxidation of certain precarcinogens and drugs and is the major nicotine C-oxidase. The…”
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Apolipoprotein E polymorphism predicts death from coronary heart disease in a longitudinal study of elderly finnish men by STENGARD, J. H, ZERBA, K. E, PEKKANEN, J, EHNHOLM, C, NISSINEN, A, SING, C. F

“…There is ample evidence from cross-sectional studies of an association between allelic variation of the gene coding for apolipoprotein E (apoE) and…”
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Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before clinical onset of disease by Tuomilehto, J, Zimmet, P, Mackay, I R, Koskela, P, Vidgren, G, Toivanen, L, Tuomilehto-Wolf, E, Kohtamäki, K, Stengård, J, Rowley, M J

“…We have done a study designed to ascertain the effectiveness of measuring antibodies to glutamic acid decarboxylase (anti-GAD) in predicting insulin-dependent…”
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Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene by Nickerson, D A, Taylor, S L, Fullerton, S M, Weiss, K M, Clark, A G, Stengård, J H, Salomaa, V, Boerwinkle, E, Sing, C F

“…A common strategy for genotyping large samples begins with the characterization of human single nucleotide polymorphisms (SNPs) by sequencing candidate regions…”
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Genotypes with the apolipoprotein epsilon4 allele are predictors of coronary heart disease mortality in a longitudinal study of elderly Finnish men by Stengård, J H, Pekkanen, J, Ehnholm, C, Nissinen, A, Sing, C F

“…Earlier we reported that allelic variation in the gene coding for apolipoprotein (apoE is a significant predictor of variation in the risk of coronary heart…”
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Diabetes mellitus, impaired glucose tolerance and mortality among elderly men: the Finnish cohorts of the Seven Countries Study by Stengård, J H, Tuomilehto, J, Pekkanen, J, Kivinen, P, Kaarsalo, E, Nissinen, A, Karvonen, M J

“…We studied the association of glucose intolerance with total and cause-specific mortality during a 5-year follow-up of 637 elderly Finnish men aged 65 to 84…”
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Intra- and interindividual variability of hemostatic factors and traditional cardiovascular risk factors in a three-year follow-up by Salomaa, V, Rasi, V, Stengård, J, Vahtera, E, Pekkanen, J, Vartiainen, E, Ehnholm, C, Puska, P

“…Elucidation of the key role of thrombosis in cardiovascular disease events has arisen considerable interest in hemostatic factors and in the repeatability of…”
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Concordance for Type 1 (insulin-dependent) and Type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland by KAPRIO, J, TUOMILEHTO, J, KOSHENVUO, M, ROMANOV, K, REUNANEN, A, ERIKSSON, J, STENGÅRD, J, KESÄNIEM, Y. A

“…We studied the cumulative incidence, concordance rate and heritability for diabetes mellitus in a nationwide cohort of 13,888 Finnish twin pairs of the same…”
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Variation in 5' Promoter Region of the APOE gene Contributes to Predicting Ischemic Heart Disease (IHD) in the Population at Large: the Copenhagen City Heart Study by Stengård, J. H., Frikke‐Schmidt, R., Tybjærg‐Hansen, A., Nordestgaard, B.G., Sing, C.F.

“…Summary The objective of this study was to evaluate whether an increased hazard of developing ischemic heart disease (IHD) is associated with any of the three…”
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Genes, Environment, and Cardiovascular Disease by Sing, Charles F, Stengård, Jari H, Kardia, Sharon L.R

“…ABSTRACT—In this essay, we call to attention what every medical researcher knows about the etiology of cardiovascular disease but most deny, or choose to…”
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Prevalence of coronary heart disease and associated risk factors among elderly Finnish men in the Seven Countries Study by Tervahauta, M, Pekkanen, J, Kivinen, P, Stengård, J, Jauhiainen, M, Ehnholm, C, Nissinen, A

“…The prevalence of coronary heart disease (CHD), cardiovascular disease (CVD) and associated risk factors was studied in 413 men aged 70-89, the survivors of…”
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Glucokinase gene polymorphisms: a genetic marker for glucose intolerance in a cohort of elderly Finnish men by McCarthy, M I, Hitman, G A, Hitchins, M, Riikonen, A, Stengård, J, Nissinen, A, Tuomilehto-Wolf, E, Tuomilehto, J

“…Although mutations in the glucokinase gene are implicated in the pathogenesis of glucose intolerance in pedigrees with maturity-onset diabetes of the young,…”
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Hypertriglyceridemia in different degrees of glucose intolerance in a Finnish population-based study by Salomaa, V V, Tuomilehto, J, Jauhiainen, M, Korhonen, H J, Stengård, J, Uusitupa, M, Pitkanen, M, Penttila, I

“…Hypertriglyceridemia in different degrees of glucose intolerance in a Finnish population-based study. V V Salomaa , J Tuomilehto , M Jauhiainen , H J Korhonen…”
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Prevalence of diabetes mellitus and impaired glucose tolerance in the middle-aged population of three areas in Finland by Tuomilehto, J, Korhonen, H J, Kartovaara, L, Salomaa, V, Stengård, J H, Pitkänen, M, Aro, A, Javela, K, Uusitupa, M, Pitkäniemi, J

“…The prevalence of diabetes mellitus and impaired glucose tolerance (IGT) was determined in a random sample of the population aged 45-64 years in three areas of…”
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Apolipoprotein E Variation at the Sequence Haplotype Level: Implications for the Origin and Maintenance of a Major Human Polymorphism by Fullerton, Stephanie M., Clark, Andrew G., Weiss, Kenneth M., Nickerson, Deborah A., Taylor, Scott L., Stengård, Jari H., Salomaa, Veikko, Vartiainen, Erkki, Perola, Markus, Boerwinkle, Eric, Sing, Charles F.

“…Three common protein isoforms of apolipoprotein E (apoE), encoded by the η2, η3, and η4 alleles of the APOE gene, differ in their association with…”
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Dietary intake of 70- to 89-year-old men in eastern and western Finland by Räsänen, L, Mutanen, M, Pekkanen, J, Laitinen, S, Koski, K, Halonen, S, Kivinen, P, Stengård, J, Nissinen, A

“…A detailed dietary history interview of 70- to 89-year-old men, 98 from eastern and 129 from western Finland, was obtained as part of a 30-year follow-up…”
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An ecological study of association between coronary heart disease mortality rates in men and the relative frequencies of common allelic variations in the gene coding for apolipoprotein E by STENGARD, J. H, WEISS, K. M, SING, C. F

“…Three common alleles, epsilon2, epsilon3, and epsilon4, of the gene coding for apolipoprotein E (apoE) have been identified as predictors of interindividual…”
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