Search Results - "Stenersen, Jakob Mørkved"
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The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation
Published in Cellular and molecular life sciences : CMLS (01-12-2024)“…Intercellular communication via gap junctions has a fundamental role in regulating cell growth and tissue homeostasis, and its dysregulation may be involved in…”
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Journal Article -
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ABCA7-dependent induction of neuropeptide Y is required for synaptic resilience in Alzheimer’s disease through BDNF/NGFR signaling
Published in Cell genomics (11-09-2024)“…Genetic variants in ABCA7, an Alzheimer’s disease (AD)-associated gene, elevate AD risk, yet its functional relevance to the etiology is unclear. We generated…”
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Co-occurring mutations identify prognostic subgroups of microsatellite stable colorectal cancer
Published in Molecular cancer (25-11-2024)“…Co-occurring mutations in pairs of genes can pinpoint clinically relevant subgroups of cancer. Most colorectal cancers (CRCs) are microsatellite stable (MSS)…”
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Journal Article