Search Results - "Stelter, Felix"

Lipopolysaccharide-binding protein is required to combat a murine Gram-negative bacterial infection by Jack, Robert S, Fan, Xiaolong, Bernheiden, Martin, Rune, Gabriele, Ehlers, Monika, Weber, Albert, Kirsch, Gerhard, Mentel, Renate, Fürll, Birgit, Freudenberg, Marina, Schmitz, Gerd, Stelter, Felix, Schütt, Christine

“…An invading pathogen must be held in check by the innate immune system until a specific immune response can be mounted. In the case of Gram-negative bacteria,…”
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Myeloid-related protein 8/14 complex describes microcirculatory alterations in patients with type 2 diabetes and nephropathy by Burkhardt, Klaus, Schwarz, Sonja, Pan, Chengrui, Stelter, Felix, Kotliar, Konstantin, Von Eynatten, Maxilian, Sollinger, Daniel, Lanzl, Ines, Heemann, Uwe, Baumann, Marcus

“…Inflammation contributes to cardiovascular complications in type 2 diabetes, which are often characterized by microvascular alterations. We investigated…”
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The novel subset of CD14+/CD16+ blood monocytes exhibits features of tissue macrophages by Ziegler-Heitbrock, H W, Fingerle, G, Ströbel, M, Schraut, W, Stelter, F, Schütt, C, Passlick, B, Pforte, A

“…The CD14+/CD16+ cells account for about 10% of all blood monocytes. They are characterized by a low level expression of the CD14 molecule and a high level…”
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Elevated levels of lipopolysaccharide-binding protein and soluble CD14 in plasma in neonatal early-onset sepsis by Berner, Reinhard, Fürll, Birgitt, Stelter, Felix, Dröse, Jana, Müller, Hans-Peter, Schütt, Christine

“…No data on lipopolysaccharide-binding protein (LBP) in newborns with sepsis have been available up to now. We therefore determined levels of LBP and soluble…”
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LPS-binding protein and CD14-dependent attachment of hepatitis B surface antigen to monocytes is determined by the phospholipid moiety of the particles by Vanlandschoot, Peter, Van Houtte, Freya, Roobrouck, Annelies, Farhoudi, Ali, Stelter, Felix, Peterson, Darell L, Gomez-Gutierrez, Julian, Gavilanes, Francisco, Leroux-Roels, Geert

“…Center for Vaccinology, Department of Clinical Biology, Microbiology and Immunology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium 1…”
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Soluble lipopolysaccharide receptor (CD14) is released via two different mechanisms from human monocytes and CD14 transfectants by Bufler, P, Stiegler, G, Schuchmann, M, Hess, S, Krüger, C, Stelter, F, Eckerskorn, C, Schütt, C, Engelmann, H

“…The receptor for lipopolysaccharide LPS (CD14) exists in a membrane-associated (mCD14) and a soluble form (sCD14). Previous studies indicate that monocytes…”
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Structures in Bacillus subtilis Are Recognized by CD14 in a Lipopolysaccharide Binding Protein-Dependent Reaction by XIAOLONG FAN, STELTER, F, MENZEL, R, JACK, R, SPREITZER, I, HARTUNG, T, SCHÜTT, C

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Macrophages as main inducers of IFN‐γ in T cells following administration of human and mouse heat shock protein 60 by Breloer, Minka, Moré, Solveig H., Osterloh, Anke, Stelter, Felix, Jack, Robert S., Bonin, Arne von

“…Human Hsp60 (hHsp60) elicits a potent pro‐inflammatory response in cells of the innate immune system. Here we compared the capacity of peritoneal exudate cells…”
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Lipopolysaccharide and ceramide docking to CD14 provokes ligand‐specific receptor clustering in rafts by Pfeiffer, Alexandra, Böttcher, Alfred, Orsó, Evelyn, Kapinsky, Michael, Nagy, Peter, Bodnár, Andrea, Spreitzer, Ingo, Liebisch, Gerhard, Drobnik, Wolfgang, Gempel, Klaus, Horn, Markus, Holmer, Stefan, Hartung, Thomas, Multhoff, Gabriele, Schütz, Gerhard, Schindler †, Hansgeorg, Ulmer, Artur J., Heine, Holger, Stelter, Felix, Schütt, Christine, Rothe, Gregor, Szöllôsi, János, Damjanovich, Sándor, Schmitz, Gerd

“…The glycosylphosphatidylinositol‐anchored receptor CD14 plays a major role in the inflammatory response of monocytes to lipopolysaccharide. Here, we describe…”
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The Myeloid Differentiation Antigen CD14 is N‐ and O‐Glycosylated by Stelter, Felix, Pfister, Martin, Bernheiden, Martin, Jack, Robert S., Bufler, Philip, Engelmann, Hartmut, Schütt, Christine

“…The myeloid differentiation antigen CD14 acts as the major receptor for bacterial lipopolysaccharide (LPS). A soluble form of the protein (sCD14) is present in…”
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Soluble CD14 acts as a negative regulator of human T cell activation and function by Nores, Julia E. Rey, Bensussan, Armand, Vita, Natalio, Stelter, Felix, Arias, Mauricio A., Jones, Matthew, Lefort, Sylvie, Borysiewicz, Leszek K., Ferrara, Pascual, Labéta, Mario O.

“…T cell activation is controlled by the coordination of stimulatory and negative regulatory signals which are not completely defined. In this study we tested…”
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Monocytes can phagocytose Gram-negative bacteria by a CD14-dependent mechanism by Grunwald, U, Fan, X, Jack, RS, Workalemahu, G, Kallies, A, Stelter, F, Schutt, C

“…Phagocytosis of bacteria by monocytes and neutrophil granulocytes provides an important first line of defense against bacterial infections. Opsonization of…”
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Cutting Edge: Human B Cell Function Is Regulated by Interaction with Soluble CD14: Opposite Effects on IgG1 and IgE Production by Arias, Mauricio A, Rey Nores, Julia E, Vita, Natalio, Stelter, Felix, Borysiewicz, Leszek K, Ferrara, Pascual, Labeta, Mario O

“…The mechanism(s) controlling activation of naive B cells, their proliferation, Ag receptor affinity maturation, isotype switching, and their fate as memory or…”
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Macrophages as main inducers of IFN-[gamma] in T cells following administration of human and mouse heat shock protein 60 by Breloer, Minka, More, Solveig H, Osterloh, Anke, Stelter, Felix, Jack, Robert S, Arne von Bonin

“…Human Hsp60 (hHsp60) elicits a potent pro-inflammatory response in cells of the innate immune system. Here we compared the capacity of peritoneal exudate cells…”
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Both membrane-bound and soluble forms of CD14 bind to gram-negative bacteria by Jack, R S, Grunwald, U, Stelter, F, Workalemahu, G, Schütt, C

“…Tissue macrophages and their precursors-the blood monocytes-respond rapidly to a bacterial infection with the release of inflammatory mediators. These…”
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Differential Impact of Substitution of Amino Acids 9-13 and 91-101 of Human CD14 on Soluble CD14-Dependent Activation of Cells by Lipopolysaccharide by Stelter, Felix, Loppnow, Harald, Menzel, Rene, Grunwald, Uwe, Bernheiden, Martin, Jack, Robert S, Ulmer, Artur J, Schutt, Christine

“…The soluble form of the endotoxin receptor CD14 is required for the LPS-induced activation of cells lacking membrane-bound CD14. It has been shown that a…”
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CHO transfectants produce large amounts of recombinant protein in suspension culture by Schütt, Christine, Fürll, Birgitt, Stelter, Felix, Jack, Robert S, Witt, Sabine

“…Chinese hamster ovary (CHO) cells transfected with various genes are widely used as adherent cell monolayers to produce recombinant proteins. In this report we…”
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Mutation of Amino Acids 39–44 of Human CD14 Abrogates Binding of Lipopolysaccharide and Escherichia coli by Stelter, Felix, Bernheiden, Martin, Menzel, René, Jack, Robert S., Witt, Sabine, Fan, Xiaolong, Pfister, Martin, Schütt, Christine

“…As a key receptor for lipopolysaccharide (LPS) on the surface of monocytes and macrophages, the CD14 molecule is primarily involved in non‐specific host…”
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The myeloid differentiation antigen CD14 is N- and O-glycosylated. Contribution of N-linked glycosylation to different soluble CD14 isoforms by Stelter, F, Pfister, M, Bernheiden, M, Jack, R S, Bufler, P, Engelmann, H, Schütt, C

“…The myeloid differentiation antigen CD14 acts as the major receptor for bacterial lipopolysaccharide (LPS). A soluble form of the protein (sCD14) is present in…”
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LBP, CD14, TLR4 and the murine innate immune response to a peritoneal Salmonella infection by Bernheiden, M, Heinrich, J M, Minigo, G, Schütt, C, Stelter, F, Freeman, M, Golenbock, D, Jack, R S

“…In mice, defense against an intraperitoneal Salmonella infection depends on a vigorous innate immune response. Mutations which lead to an inadequate early…”
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