Search Results - "Stek, M.L"
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Loneliness in older adults is associated with diminished cortisol output
Published in Journal of psychosomatic research (01-04-2017)“…Abstract Objective Loneliness in older adults has been associated with increased mortality and health problems. One of the assumed underlying mechanisms is…”
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Big Five personality and depression diagnosis, severity and age of onset in older adults
Published in Journal of affective disorders (01-10-2013)“…Abstract Background Personality may play an important role in late-life depression. The aim of this study is to examine the association between the Big Five…”
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Hypothalamic–pituitary–adrenal axis activity in older persons with and without a depressive disorder
Published in Psychoneuroendocrinology (01-01-2015)“…Highlights • Older, depressed persons have higher cortisol levels at awakening than non-depressed controls. • The stress response system of older, depressed…”
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Insulin-like growth factor–1 and risk of late-onset Alzheimer's disease: findings from a family study
Published in Neurobiology of aging (01-03-2014)“…Abstract Insulin-like growth factor–1 (IGF-1), part of an evolutionary conserved signaling pathway in both mammalian and non-mammalian species, is inferred in…”
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Gender differences in the relation between depression and social support in later life
Published in International psychogeriatrics (01-01-2013)“…Prevalence of depression is twice as high in women as in men, also in older adults. Lack of social support is a risk factor for late-life depression. The…”
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Early complete remitters after electroconvulsive therapy: profile and prognosis
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Childhood abuse, family history and stressors in older patients with bipolar disorder in relation to age at onset
Published in Journal of affective disorders (15-09-2015)“…Abstract Objectives The aim of this study is to explore the family history of psychiatric disorders, childhood abuse, and stressors in older patients with…”
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Depressive subtypes in an elderly cohort identified using latent class analysis
Published in Journal of affective disorders (15-08-2017)“…Abstract Background Clinical findings indicate heterogeneity of depressive disorders, stressing the importance of subtyping depression for research and…”
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The Structure of the Geriatric Depressed Brain and Response to ECT
Published in European psychiatry (28-03-2015)“…Seven to twelve year follow-up of ECT outcome in patients with geriatric depression. Do these patients develop dementia? Introduction Depression and cognitive…”
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Inter-individual variability of neurocognitive performances after electroconvulsive therapy in depressed patients: improvement and decline
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Genome-wide meta-analysis of DNA methylation changes associated with antidepressant effects of Electroconvulsive Therapy
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Exploring resting state connectivity in ECT patients with psychotic depression
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Reliability of retrospective reports on childhood abuse and its determinants in older adults during a 6-year follow-up
Published in Journal of psychiatric research (01-10-2018)“…Controversy exists concerning the reliability of retrospective self-reports on childhood abuse since this method might be subject to under- or overreporting…”
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Age modifies the association between apathy and recurrent falling in Dutch ambulant older persons with a high fall risk
Published in Experimental gerontology (02-10-2018)“…Apathy, a common and disabling behavioural syndrome in older persons, has been associated with impaired physical performance and executive dysfunction. Both…”
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Inflammatory markers and cortisol parameters across depressive subtypes in an older cohort
Published in Journal of affective disorders (01-07-2018)“…There is growing evidence that inflammatory and cortisol dysregulation are underlying pathophysiological mechanisms in the aetiology of major depressive…”
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Big Five personality characteristics are associated with depression subtypes and symptom dimensions of depression in older adults
Published in International journal of geriatric psychiatry (01-12-2017)“…Objective This study examined the associations of personality characteristics with both subtypes and symptom dimensions of depression in older adults. Methods…”
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Freezing of gait and major depressive disorder responding both to electroconvulsive therapy
Published in Parkinsonism & related disorders (01-09-2019)“…•Major depressive disorder (MDD) can be accompanied by freezing of gait.•Bradykinesia in MDD could be due to dopamine deficiency in basal ganglia.•ECT is…”
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The course of apathy in late‐life depression treated with electroconvulsive therapy; a prospective cohort study
Published in International journal of geriatric psychiatry (01-09-2018)“…Objectives Apathy, a lack of motivation, is frequently seen in older individuals, with and without depression, with substantial impact on quality of life. This…”
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The tide has turned: incidence of depression declined in community living young-old adults over one decade
Published in Epidemiology and psychiatric sciences (26-01-2019)“…Studying birth-cohort differences in depression incidence and their explanatory factors may provide insight into the aetiology of depression and could help to…”
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