Search Results - "Steinman, L"

Inverse vaccination, the opposite of Jenner’s concept, for therapy of autoimmunity by Steinman, L.

“…  Steinman L (Stanford University, Stanford, CA, USA). Inverse vaccination, the opposite of Jenner’s concept, for therapy of autoimmunity (foresight). J…”
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Why are prions and amyloid structures immune suppressive and other intriguing questions facing neuroimmunologists in the future by Steinman, L.

“…The immune system plays a major role in certain diseases of the brain like multiple sclerosis and neuromyelitis optica, while the brain may play a major role…”
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Myelin-specific CD8 T cells in the pathogenesis of experimental allergic encephalitis and multiple sclerosis by Steinman, L

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A scientific sequel to Stieg Larsson: relationship between Pandemrix – pandemic influenza vaccine – and the subsequent development of narcolepsy by Fugger, L., Steinman, L.

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The pharmacokinetics and dosing of oral 4‐methylumbelliferone for inhibition of hyaluronan synthesis in mice by Kuipers, H. F., Nagy, N., Ruppert, S. M., Sunkari, V. G., Marshall, P. L., Gebe, J. A., Ishak, H. D., Keswani, S. G., Bollyky, J., Frymoyer, A. R., Wight, T. N., Steinman, L., Bollyky, P. L.

“…Summary Recently, there has been considerable interest in using 4‐methylumbelliferone (4‐MU) to inhibit hyaluronan (HA) synthesis in mouse models of cancer,…”
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Tryptophan degradation in autoimmune diseases by Opitz, C A, Wick, W, Steinman, L, Platten, M

“…Recent evidence points to tryptophan (Trp) degradation as a potent immunosuppressive mechanism involved in the maintenance of immunological tolerance. Both Trp…”
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Functional rescue of experimental ischemic optic neuropathy with αB-crystallin by Pangratz-Fuehrer, S, Kaur, K, Ousman, S S, Steinman, L, Liao, Y J

“…Purpose Anterior ischemic optic neuropathy (AION) is an important cause of acute vision loss in adults, and there is no effective treatment. We studied early…”
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Serum IL-17F does not predict poor response to IM IFN beta -1a in relapsing-remitting MS by Bushnell, SE, Zhao, Z, Stebbins, C C, Cadavid, D, Buko, A M, Whalley, E T, Davis, JA, Versage, E M, Richert, J R, Axtell, R C, Steinman, L, Medori, R

“…Objective: There is a significant unmet need for serum biomarkers in relapsing-remitting multiple sclerosis (RRMS) that are predictive of therapeutic response…”
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The coming of age for antigen-specific therapy of multiple sclerosis by Steinman, L.

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Serum IL-17F does not predict poor response to IM IFNβ-1a in relapsing-remitting MS by BUSHNELL, S. E, ZHAO, Z, STEINMAN, L, MEDORI, R, STEBBINS, C. C, CADAVID, D, BUKO, A. M, WHALLEY, E. T, DAVIS, J. A, VERSAGE, E. M, RICHERT, J. R, AXTELL, R. C

“…There is a significant unmet need for serum biomarkers in relapsing-remitting multiple sclerosis (RRMS) that are predictive of therapeutic response to…”
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A Few Autoreactive Cells in an Autoimmune Infiltrate Control a Vast Population of Nonspecific Cells: A Tale of Smart Bombs and the Infantry by Steinman, Lawrence

“…Inflammatory infiltrates in tissue-specific autoimmune disease comprise a collection of T cells with specificity for an antigen in the target organ. These…”
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Gene Microarray Identification of Redox and Mitochondrial Elements That Control Resistance or Sensitivity to Apoptosis by Voehringer, D W, Hirschberg, D L, Xiao, J, Lu, Q, Roederer, M, Lock, C B, Herzenberg, L A, Steinman, L

“…Multigenic programs controlling susceptibility to apoptosis in response to ionizing radiation have not yet been defined. Here, using DNA microarrays, we show…”
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Immunotherapy of multiple sclerosis: the end of the beginning by Steinman, Lawrence

“…Currently available medicines approved for use in Europe and North America reduce the relapse rate in relapsing/remitting multiple sclerosis by about 30%…”
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Polyarginine enters cells more efficiently than other polycationic homopolymers by Mitchell, D.J., Steinman, L., Kim, D.T., Fathman, C.G., Rothbard, J.B.

“…: Homopolymers or peptides containing a high percentage of cationic amino acids have been shown to have a unique ability to cross the plasma membrane of cells,…”
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Some misconceptions about understanding autoimmunity through experiments with knockouts by Steinman, L

“…Experimental autoimmune encephalomyelitis (EAE) has served as a prototypic model of T cell-mediated, organ-specific autoimmune disease, and as a useful model…”
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Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease by Hauben, E, Agranov, E, Gothilf, A, Nevo, U, Cohen, A, Smirnov, I, Steinman, L, Schwartz, M

“…Spinal cord injury results in a massive loss of neurons, and thus of function. We recently reported that passive transfer of autoimmune T cells directed…”
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Risk factors associated with exertional medial tibial pain: a 12 month prospective clinical study by Burne, S G, Khan, K M, Boudville, P B, Mallet, R J, Newman, P M, Steinman, L J, Thornton, E

“…Objective: To investigate in a military setting the potential role of intrinsic biomechanical and anthropometric risk factors for, and the incidence of,…”
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Blockade of gamma interferon might be beneficial in MS by Steinman, L.

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Elaborate interactions between the immune and nervous systems by Steinman, Lawrence

“…The immune system and the nervous system maintain extensive communication, including 'hardwiring' of sympathetic and parasympathetic nerves to lymphoid organs…”
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Gene microarrays and experimental demyelinating disease: a tool to enhance serendipity by Steinman, L

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