Search Results - "Steinle, Roxanne"

CS1, a Potential New Therapeutic Antibody Target for the Treatment of Multiple Myeloma by Hsi, Eric D, Steinle, Roxanne, Balasa, Balaji, Szmania, Susann, Draksharapu, Aparna, Shum, Benny P, Huseni, Mahrukh, Powers, David, Nanisetti, Amulya, Zhang, Yin, Rice, Audie G, van Abbema, Anne, Wong, Melanie, Liu, Gao, Zhan, Fenghuang, Dillon, Myles, Chen, Shihao, Rhodes, Susan, Fuh, Franklin, Tsurushita, Naoya, Kumar, Shankar, Vexler, Vladimir, Shaughnessy, Jr, John D, Barlogie, Bart, van Rhee, Frits, Hussein, Mohamad, Afar, Daniel E H, Williams, Marna B

“…Purpose: We generated a humanized antibody, HuLuc63, which specifically targets CS1 (CCND3 subset 1, CRACC, and SLAMF7), a cell surface glycoprotein not…”
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Mammalian Target of Rapamycin (mTOR) Regulates Cellular Proliferation and Tumor Growth in Urothelial Carcinoma by Hansel, Donna E, Platt, Eric, Orloff, Mohammed, Harwalker, Jyoti, Sethu, Swathi, Hicks, Jessica L, De Marzo, Angelo, Steinle, Roxanne E, Hsi, Eric D, Theodorescu, Dan, Ching, Christina B, Eng, Charis

“…Mammalian target of rapamycin (mTOR) signaling has been associated with aggressive tumor growth in many cancer models, although its role in urothelial…”
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A simple and fast liquid chromatography–tandem mass spectrometry method for measurement of underivatized l-arginine, symmetric dimethylarginine, and asymmetric dimethylarginine and establishment of the reference ranges by El-Khoury, Joe M., Bunch, Dustin R., Reineks, Edmunds, Jackson, Raymond, Steinle, Roxanne, Wang, Sihe

“…Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase and an established biomarker for endothelial function, while symmetric…”
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Antibodies to TWEAK Receptor Inhibit Human Tumor Growth through Dual Mechanisms by Culp, Patricia A, Choi, Donghee, Zhang, Yongke, Yin, Johnny, Seto, Pui, Ybarra, Suzanne E, Su, Mian, Sho, Mien, Steinle, Roxanne, Wong, Melanie H L, Evangelista, Ferdinand, Grove, Jennifer, Cardenas, Marie, James, Marjorie, Hsi, Eric D, Chao, Debra T, Powers, David B, Ramakrishnan, Vanitha, Dubridge, Robert

“…Purpose: Targeted therapeutics have significantly changed the outcome for patients diagnosed with cancer. Still, effective therapeutic intervention does not…”
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Expression of bcl-2 in Classical Hodgkin's Lymphoma: An Independent Predictor of Poor Outcome by SUP, Stephen J, ALEMAHY, Carlos A, POHLMAN, Brad, ELSON, Paul, MALHI, Serena, THAKKAR, Snehal, STEINIE, Roxanne, HSI, Eric D

“…Although most classical Hodgkin's lymphoma (CHL) patients are cured, a significant minority fails primary therapy and may die as a result of their disease…”
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Highly sensitive measurement of whole blood chromium by inductively coupled plasma mass spectrometry by Cieslak, Wendy, Pap, Kathleen, Bunch, Dustin R., Reineks, Edmunds, Jackson, Raymond, Steinle, Roxanne, Wang, Sihe

“…Chromium (Cr), a trace metal element, is implicated in diabetes and cardiovascular disease. A hypochromic state has been associated with poor blood glucose…”
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Fast, simple, and sensitive high‐performance liquid chromatography method for measuring vitamins A and E in human blood plasma by Yuan, Chao, Burgyan, Maria, Bunch, Dustin R, Reineks, Edmunds, Jackson, Raymond, Steinle, Roxanne, Wang, Sihe

“…Vitamins A and E are fat‐soluble vitamins that play important roles in several physiological processes. Monitoring their concentrations is needed to detect…”
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Predictors of outcome in post-transplant lymphoproliferative disorder: an evaluation of tumor infiltrating lymphocytes in the context of clinical factors by Richendollar, Bill G., Tsao, Raymond E., Elson, Paul, Jin, Tao, Steinle, Roxanne, Pohlman, Brad, Hsi, Eric D.

“…We hypothesized that the number of tumor infiltrating cytotoxic T-cells (CTCs) and regulatory T-cells (Tregs), shown to have prognostic value in other…”
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CS-1 Is Expressed in Nasal Type NK/T Cell Lymphomas and Angioimmunoblastic T-Cell Lymphomas: Implications for Targeted Therapy with Elotuzumab (HuLuc63) by Hsi, Eric D, Steinle, Roxanne, Balasa, Balaji, Rice, Audie, Ko, Young-Hyeh, Afar, Daniel E.H.

“…Background: CS-1 (CRACC, SLAMF7, CD319) is a member of the signaling lymphocyte activating molecule-related receptor family. It is highly and uniformly…”
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Elotuzumab (HuLuc63) Activates CD56dim Natural Killer Cells and Monocytes Resulting in the Release of IP-10 and MCP-1 by Balasa, Balaji, Huseni, Mahrukh, Cherukuri, Jyothi, Steinle, Roxanne, Nanisetti, Amulya, Afar, Daniel, Hsi, Eric, Vexler, Vladimir

“…Elotuzumab (formerly known as HuLuc63) is a humanized monoclonal antibody targeting CS1 (CD319, SLAMF7), a protein which is highly and uniformly expressed on…”
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ZAP-70 expression in B-cell hematologic malignancy is not limited to CLL/SLL by SUP, Stephen J, DOMIATI-SAAD, Rana, KELLEY, Todd W, STEINLE, Roxanne, XINYU ZHAO, HSI, Eric D

“…ZAP-70 is a tyrosine kinase expressed in normal T cells and NK cells. Expression of ZAP-70 has been associated with poor prognosis in B-cell chronic…”
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CS1: A Potential New Therapeutic Target for the Treatment of Multiple Myeloma by Hsi, Eric D., Steinle, Roxanne, Balasa, Balaji, Draksharapu, Aparna, Shum, Benny, Huseni, Marukh, Powers, David, Nanisetti, Amulya, Williams, Marna, Vexler, Vladimir, Hussein, Mohamad, Afar, Daniel

“…Background: To identify genes upregulated in human memory B and plasma cells, naïve B cell cDNA was subtracted from plasma cell and memory B cell cDNA. One…”
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