Search Results - "Steinhoff, Tiana"
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Alzheimer disease-associated cystatin C variant undergoes impaired secretion
Published in Neurobiology of disease (01-06-2003)“…CST3 is the coding gene for cystatin C (CysC). CST3 B/B homozygosity is associated with an increased risk of developing Alzheimer disease. We performed CysC…”
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Increased Cystatin C in Astrocytes of Transgenic Mice Expressing the K670N-M671L Mutation of the Amyloid Precursor Protein and Deposition in Brain Amyloid Plaques
Published in Neurobiology of disease (01-08-2001)“…Cystatin C is an essential secretory cofactor for neurogenesis with potent protease inhibitor activities. Polymorphisms of cystatin C are genetically…”
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Quantitative detection of therapeutic proteins and their metabolites in serum using antibody-coupled ProteinChip® Arrays and SELDI-TOF-MS
Published in Journal of immunological methods (20-12-2006)“…One of the important steps in developing protein therapeutics is the determination of their preliminary PK in vivo. These data are essential to design optimal…”
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Journal Article