Search Results - "Steinhofel, Kathleen"

Long Non-coding RNA Structure and Function: Is There a Link? by Zampetaki, Anna, Albrecht, Andreas, Steinhofel, Kathleen

“…RNA has emerged as the prime target for diagnostics, therapeutics and the development of personalized medicine. In particular, the non-coding RNAs (ncRNAs)…”
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New bounds for single-machine time-dependent scheduling with uniform deterioration by Gkikas, Angelos, Letsios, Dimitrios, Radzik, Tomasz, Steinhöfel, Kathleen

“…We consider the single-machine time-dependent scheduling problem with linearly deteriorating jobs arriving over time. Each job i is associated with a release…”
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Mask use, risk-mitigation behaviours and pandemic fatigue during the COVID-19 pandemic in five cities in Australia, the UK and USA: A cross-sectional survey by MacIntyre, Chandini Raina, Nguyen, Phi-Yen, Chughtai, Abrar Ahmad, Trent, Mallory, Gerber, Brian, Steinhofel, Kathleen, Seale, Holly

“…•This was a cross-sectional survey in five cities without a culture of wearing masks.•Mask use decreased after the age of 50 years but this age effect was not…”
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Extended endocrine therapy in breast cancer: A basket of length-constraint feature selection metaheuristics to balance Type I against Type II errors by Liu, Hua-Ping, Zhang, Jian V., Wang, Dongwen, Albrecht, Andreas, Steinhöfel, Kathleen, Lai, Hung-Ming

“…[Display omitted] •Genomic tests designed for early recurrence risks might not be suitable for 10-year recurrence.•60.97 was identified as a new cutoff of…”
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Corrigendum: Long Non-coding RNA Structure and Function: Is There a Link? by Zampetaki, Anna, Albrecht, Andreas, Steinhofel, Kathleen

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CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function by Lataniotis, Lazaros, Albrecht, Andreas, Kok, Fatma O., Monfries, Clinton A. L., Benedetti, Lorena, Lawson, Nathan D., Hughes, Simon M., Steinhofel, Kathleen, Mayr, Manuel, Zampetaki, Anna

“…MicroRNAs (miRNAs) are important regulators of diverse physiological and pathophysiological processes. MiRNA families and clusters are two key features in…”
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Accessibility of microRNA binding sites in metastable RNA secondary structures in the presence of SNPs by Day, Luke, Abdelhadi Ep Souki, Ouala, Albrecht, Andreas A, Steinhöfel, Kathleen

“…We study microRNA (miRNA) bindings to metastable RNA secondary structures close to minimum free energy conformations in the context of single nucleotide…”
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A new heuristic method for approximating the number of local minima in partial RNA energy landscapes by Albrecht, Andreas A., Day, Luke, Abdelhadi Ep Souki, Ouala, Steinhöfel, Kathleen

“…[Display omitted] •We propose a new pooling procedure and evaluation strategy for sampling data over energy landscapes.•The new method is embedded into the…”
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Random versus Deterministic Descent in RNA Energy Landscape Analysis by Day, Luke, Abdelhadi Ep Souki, Ouala, Albrecht, Andreas A., Steinhöfel, Kathleen

“…Identifying sets of metastable conformations is a major research topic in RNA energy landscape analysis, and recently several methods have been proposed for…”
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Derivative scores from site accessibility and ranking of miRNA target predictions by Ullah, Abu Z M Dayem, Sahoo, Sudhakar, Steinhöfel, Kathleen, Albrecht, Andreas A

“…In the present study, we define derivative scoring functions from PITA and STarMir predictions. The scoring functions are evaluated for up to five selected…”
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iRDA: a new filter towards predictive, stable, and enriched candidate genes by Lai, Hung-Ming, Albrecht, Andreas A, Steinhöfel, Kathleen K

“…Gene expression profiling using high-throughput screening (HTS) technologies allows clinical researchers to find prognosis gene signatures that could better…”
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Combinatorial Landscape Analysis for k-SAT Instances by Albrecht, A.A., Lane, P.C.R., Steinhofel, K.

“…Over the past ten years, methods from statistical physics have provided a deeper inside into the average complexity of hard combinatorial problems, culminating…”
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A hybrid approach to protein folding problem integrating constraint programming with local search by Ullah, Abu Dayem, Steinhöfel, Kathleen

“…The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and…”
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A firefly-inspired method for protein structure prediction in lattice models by Maher, Brian, Albrecht, Andreas A, Loomes, Martin, Yang, Xin-She, Steinhöfel, Kathleen

“…We introduce a Firefly-inspired algorithmic approach for protein structure prediction over two different lattice models in three-dimensional space. In…”
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Search Based Approaches to Component Selection and Prioritization for the Next Release Problem by Baker, P., Harman, M., Steinhofel, K., Skaliotis, A.

“…This paper addresses the problem of determining the next set of releases in the course of software evolution. It formulates both ranking and selection of…”
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Computer-assisted diagnosis of focal liver lesions on CT images evaluation of the Perceptron algorithm by Hein, Eike, Albrecht, Andreas, Melzer, Daniela, Steinhöfel, Kathleen, Rogalla, Patrik, Hamm, Bernd, Taupitz, Matthias

“…The purpose of the study was to investigate a modified version of a so-called Perceptron algorithm in detecting focal liver lesions on CT scans. The modified…”
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Converging and emerging threats to health security by Raina MacIntyre, C., Engells, Thomas Edward, Scotch, Matthew, Heslop, David James, Gumel, Abba B., Poste, George, Chen, Xin, Herche, Wesley, Steinhöfel, Kathleen, Lim, Samsung, Broom, Alex

“…Advances in biological sciences have outpaced regulatory and legal frameworks for biosecurity. Simultaneously, there has been a convergence of scientific…”
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A new vision of evaluating gene expression signatures by Lai, Hung-Ming, Özturk, Celal, Albrecht, Andreas, Steinhöfel, Kathleen

“…[Display omitted] •Uniqueness, parsimony, and best performance of gene signatures should not be the only issues of concern.•Multiple near-optimal gene…”
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The convergence of stochastic algorithms solving flow shop scheduling by Steinhöfel, K., Albrecht, A., Wong, C.K.

“…In the paper, we apply logarithmic cooling schedules of simulated annealing-based algorithms to flow shop scheduling. In our problem setting, the objective to…”
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New Bounds for Time-Dependent Scheduling with Uniform Deterioration by Gkikas, Angelos, Letsios, Dimitrios, Radzik, Tomasz, Steinhöfel, Kathleen

“…Time-dependent scheduling with linear deterioration involves determining when to execute jobs whose processing times degrade as their beginning is delayed…”
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