Search Results - "Steinhardt, R. A."

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    A decrease in membrane tension precedes successful cell-membrane repair by Togo, T, Krasieva, T B, Steinhardt, R A

    Published in Molecular biology of the cell (01-12-2000)
    “…We hypothesized that the requirement for Ca(2+)-dependent exocytosis in cell-membrane repair is to provide an adequate lowering of membrane tension to permit…”
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    Journal Article
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    A critical evaluation of resting intracellular free calcium regulation in dystrophic mdx muscle by Hopf, F W, Turner, P R, Denetclaw, Jr, W F, Reddy, P, Steinhardt, R A

    Published in The American journal of physiology (01-10-1996)
    “…There are conflicting reports regarding whether resting free calcium levels ([Ca2+]i) are elevated in dystrophic mouse (mdx) myotubes and adult myofibers. We…”
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    Journal Article
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    Cell Membrane Resealing by a Vesicular Mechanism Similar to Neurotransmitter Release by Steinhardt, Richard A., Bi, Guoqiang, Alderton, Janet M.

    “…After injury to the cell membrane, rapid resealing of the membrane occurs with little loss of intracellular contents. This process has been studied by…”
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    Journal Article
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    How Calcium Influx through Calcium Leak Channels Is Responsible for the Elevated Levels of Calcium-dependent Proteolysis in Dystrophic Myotubes by Alderton, J.M, Steinhardt, R.A

    Published in Trends in Cardiovascular Medicine (01-08-2000)
    “…Duchenne muscular dystrophy patients lack the protein dystrophin which is an essential link in the complex of proteins that connect the cytoskeleton to the…”
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    Book Review Journal Article
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    Calcium-Regulated Exocytosis Is Required for Cell Membrane Resealing by Bi, Guo-Qiang, Alderton, Janet M., Steinhardt, Richard A.

    Published in The Journal of cell biology (01-12-1995)
    “…Using confocal microscopy, we visualized exocytosis during membrane resealing in sea urchin eggs and embryos. Upon wounding by a laser beam, both eggs and…”
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    Journal Article
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    Increased Calcium Influx in Dystrophic Muscle by Turner, Paul R., Fong, Peying, Denetclaw, Wilfred F., Steinhardt, Richard A.

    Published in The Journal of cell biology (01-12-1991)
    “…We examined pathways which might result in the elevated resting free calcium [Ca2+]i levels observed in dystrophic mouse (mdx) skeletal muscle fibers and…”
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    Journal Article
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    Increased activity of calcium leak channels caused by proteolysis near sarcolemmal ruptures by McCarter, G C, Steinhardt, R A

    Published in The Journal of membrane biology (15-07-2000)
    “…Dystrophin, a 427 kD membrane-associated structural protein in muscle cells, is thought to confer strength to the myofiber sarcolemma and protect the membrane…”
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    Journal Article
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    Increased Activity of Calcium Leak Channels in Myotubes of Duchenne Human and mdx Mouse Origin by Fong, Peying, Turner, Paul R., Denetclaw, Wilfred F., Steinhardt, Richard A.

    “…Elevated free Ca$^{2+}$ concentrations found in adult dystrophic muscle fibers result in enhanced protein degradation. Since the difference in concentrations…”
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    Journal Article
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    Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice by Turner, Paul R, Westwood, Tim, Regen, Chester M, Steinhardt, Richard A

    Published in Nature (London) (20-10-1988)
    “…The defective gene responsible for Duchenne muscular dystrophy in humans and the dystrophic condition in mdx mice results in a lack of dystrophin at first…”
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    Journal Article
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    Depletion of intracellular calcium stores by calcium ionophore A23187 induces the genes for glucose-regulated proteins in hamster fibroblasts by Drummond, I A, Lee, A S, Resendez, E, Steinhardt, R A

    Published in The Journal of biological chemistry (15-09-1987)
    “…Animal cells respond to calcium ionophore (A23187) treatment with the coordinate induction of a set of genes encoding proteins identical to the…”
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    Journal Article
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    Calcium misregulation and the pathogenesis of muscular dystrophy by Hopf, F W, Turner, P R, Steinhardt, R A

    Published in Sub-cellular biochemistry (2007)
    “…Although the exact nature of the relationship between calcium and the pathogenesis of Duchenne muscular dystrophy (DMD) is not fully understood, this is an…”
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    Journal Article
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    Changes of free calcium levels with stages of the cell division cycle by Poenie, Martin, Alderton, Janet, Tsien, Roger Y, Steinhardt, Richard A

    Published in Nature (London) (01-01-1985)
    “…Although the regulation of events in the cell division cycle by calcium or other cations has been the subject of much interest and speculation, experimental…”
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    Journal Article
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    Evidence for a vesicle-mediated maintenance of store-operated calcium channels in a human embryonic kidney cell line by Alderton, J.M., Ahmed, S.A., Smith, L.A., Steinhardt, R.A.

    Published in Cell calcium (Edinburgh) (01-09-2000)
    “…Direct microinjection of the clostridial neurotoxins botulinum neurotoxin A light chain or tetanus neurotoxin into cells of a human embryonic kidney cell line…”
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    Journal Article
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    Lipofection of a cDNA plasmid containing the dystrophin gene lowers intracellular free calcium and calcium leak channel activity in mdx myotubes by MCCARTER, G. C, DENETCLAW, W. F, REDDY, P, STEINHARDT, R. A

    Published in Gene therapy (01-05-1997)
    “…Muscle cells from Duchenne muscular dystrophy (DMD) patients and the dystrophic mdx mouse lack the protein dystrophin. Intracellular free calcium ([Ca2+]i) is…”
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    Journal Article
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    Calcium Influx through Calcium Leak Channels Is Responsible for the Elevated Levels of Calcium-dependent Proteolysis in Dystrophic Myotubes by Alderton, Janet M., Steinhardt, Richard A.

    Published in The Journal of biological chemistry (31-03-2000)
    “…To estimate calpain proteolysis, we measured the hydrolysis rate of a fluorogenic calpain substrate in individual resting normal and dystrophic mdx mouse…”
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    Journal Article
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    Induction of neuronal differentiation by planar signals in Xenopus embryos by Sater, Amy K., Steinhardt, Richard A., Keller, Ray

    Published in Developmental dynamics (01-08-1993)
    “…The induction of the central nervous system in amphibian embryos is mediated both by early planar signals produced by mesoderm at the dorsal lip and later…”
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    Journal Article
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    Large changes in intracellular pH and calcium observed during heat shock are not responsible for the induction of heat shock proteins in Drosophila melanogaster by DRUMMOND, I. A. S, MCCLURE, S. A, POENIE, M, TSIEN, R. Y, STEINHARDT, R. A

    Published in Molecular and Cellular Biology (01-05-1986)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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    Proteolysis results in altered leak channel kinetics and elevated free calcium in mdx muscle by TURNER, P. R, SCHULTZ, R, GANGULY, B, STEINHARDT, R. A

    Published in The Journal of membrane biology (01-05-1993)
    “…Resting free calcium levels ([Ca2+]i) are elevated in Duchenne human myotubes and mdx mouse muscle and myotubes which lack the gene product dystrophin at the…”
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    Journal Article