Search Results - "Steinfellner, W"
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Generation of human monoclonal antibodies against HIV-1 proteins; electrofusion and Epstein-Barr virus transformation for peripheral blood lymphocyte immortalization
Published in AIDS research and human retroviruses (01-04-1994)“…Electrofusion and EBV transformation were studied by immortalizing human PBLs from blood of HIV-1-positive volunteers. A panel of 33 cell lines producing human…”
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Screening for improved cell performance: Selection of subclones with altered production kinetics or improved stability by cell sorting
Published in Biotechnology and bioengineering (20-12-2004)“…One of the major problems in the biotechnology industry is the selection of cell lines well suited for production of biopharmaceutical proteins. Usually, the…”
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Stable recombinant expression of the anti HIV-1 monoclonal antibody 2F5 after IgG3/IgG1 subclass switch in CHO cells
Published in Biotechnology and bioengineering (05-01-2000)“…The human monoclonal antibody (humAb) 2F5 is a potent candidate for immunotherapy of HIV‐1. The xenohybridoma derived humAb 2F5 is of IgG3 kappa isotype…”
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Changes during subclone development and ageing of human antibody-producing recombinant CHO cells
Published in Journal of biotechnology (15-04-1999)“…Some of the problems encountered with human or human-mouse heterohybridomas, such as low growth rates and high serum requirements, have led to the increased…”
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Analysis of changes during subclone development and ageing of human antibody-producing heterohybridoma cells by Northern blot and flow cytometry
Published in Journal of biotechnology (08-01-1999)“…The economic importance of obtaining high-producing subclones for large scale production of pharmaceutical proteins is self-evident. However, few papers have…”
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