Search Results - "Steinert, P M"

Assembly of the epidermal cornified cell envelope by Kalinin, A, Marekov, L N, Steinert, P M

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Cross‐linking of ubiquitin, HSP27, parkin and α‐synuclein by γ‐glutamyl‐ε‐lysine bonds in Alzheimer's neurofibrillary tangles by Nemes, Zoltán, Devreese, Bart, Steinert, Peter M., Beeumen, Jozef Van, Fésüs, László

“…ABSTRACT The accumulation of misfolded proteins in intracellular inclusions is a generic feature of neurodegenerative disorders. Although heavily…”
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The Function of Intermediate Filaments in Cell Shape and Cytoskeletal Integrity by Goldman, Robert D., Khuon, Satya, Chou, Ying Hao, Opal, Puneet, Steinert, Peter M.

“…This study describes the development and use of a specific method for disassembling intermediate filament (IF) networks in living cells. It takes advantage of…”
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Molecular and Cellular Biology of Intermediate Filaments by Steinert, P M, Roop, D R

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Expression of Murine Epidermal Differentiation Markers Is Tightly Regulated by Restricted Extracellular Calcium Concentrations in vitro by Yuspa, Stuart H., Kilkenny, Anne E., Steinert, Peter M., Roop, Dennis R.

“…Epidermal differentiation is characterized by a series of coordinated morphological and biochemical changes which result in a highly specialized, highly…”
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Effect of AP1 Transcription Factors on the Regulation of Transcription in Normal Human Epidermal Keratinocytes by Rossi, Antonello, Jang, Shyh-Ing, Ceci, Roberta, Steinert, Peter M., Markova, Nedialka G.

“…The conversion of basal keratinocytes to spinous and granular cells is accompanied by the synthesis of a series of epidermal proteins in a…”
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Structure, Function, and Dynamics of Keratin Intermediate Filaments by Steinert, Peter M.

“…The recent widespread application of modern methods of structural biology, molecular biology, and molecular genetics has provided a wealth of new information…”
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The expression of a novel, epithelium-specific ets transcription factor is restricted to the most differentiated layers in the epidermis by Andreoli, Jeanne M., Jang, Shyh-Ing, Chung, Edward, Coticchia, Christine M., Steinert, Peter M., Markova, Nedialka G.

“…Ets proteins have been implicated in the regulation of gene expression during a variety of biological processes, including growth control, differentiation,…”
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Diversity of intermediate filament structure. Evidence that the alignment of coiled-coil molecules in vimentin is different from that in keratin intermediate filaments by Steinert, P M, Marekov, L N, Parry, D A

“…Although vimentin intermediate filaments (IF) are morphologically similar to all other IF types, cells have evolved different ways of manipulating vimentin and…”
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The two-chain coiled-coil molecule of native epidermal keratin intermediate filaments is a type I-type II heterodimer by STEINERT, P. M

“…The composition of the two-chain coiled-coil molecule of murine epidermal keratin intermediate filaments (KIF) containing keratins 1 (type II) and 10 (type I)…”
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Sjögren-Larsson syndrome is caused by mutations in the fatty aldehyde dehydrogenase gene by Hamrock, David J, Marekov, Lyuben N, Laurenzi, Vincenzo De, Rizzo, William B, Rogers, Geraldine R, Steinert, Peter M, Markova, Nelli, Compton, John G

“…Sjögren-Larsson syndrome (SLS) is an inherited neurocutaneous disorder characterized by mental retardation, spasticity and ichthyosis. SLS patients have a…”
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Mutations in the gene for transglutaminase 1 in autosomal recessive lamellar ichthyosis by Russell, Laura J, DiGiovanna, John J, Rogers, Geraldine R, Steinert, Peter M, Hashem, Nemat, Compton, John G, Bale, Sherri J

“…We recently mapped the disease locus for severe autosomal recessive lamellar ichthyosis (LI) to chromosome 14q11 and showed complete linkage with TGM1, the…”
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Protein composition of cornified cell envelopes of epidermal keratinocytes by STEVEN, A. C, STEINERT, P. M

“…Terminally differentiated mammalian epidermal cells are lined with a 15 nm thick layer of proteins cross-linked by isodipeptide and disulfide bonds, called the…”
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Comparison of molecularly cloned bullous pemphigoid antigen to desmoplakin I confirms that they define a new family of cell adhesion junction plaque proteins by TANAKA, T, PARRY, D. A. D, KLAUS-KOVTUN, V, STEINERT, P. M, STANLEY, J. R

“…Bullous pemphigoid is a subepidermal blistering disease in which patients have autoantibodies against the plaque of the hemidesmosome. Starting with a…”
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Coiled-coil trigger motifs in the 1B and 2B rod domain segments are required for the stability of keratin intermediate filaments by Wu, K C, Bryan, J T, Morasso, M I, Jang, S I, Lee, J H, Yang, J M, Marekov, L N, Parry, D A, Steinert, P M

“…Many alpha-helical proteins that form two-chain coiled coils possess a 13-residue trigger motif that seems to be required for the stability of the coiled coil…”
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The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein by SEUNG-CHUL LEE, IN-GYU LIM, MAREKOV, L. N, O'KEEFE, E. J, PARRY, D. A. D, STEINERT, P. M

“…Trichohyalin is an intermediate filament-associated protein that associates in regular arrays with keratin intermediate filaments (KIF) of the inner root…”
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Structure of the human desmoplakins. Implications for function in the desmosomal plaque by GREEN, K. J, PARRY, D. A. D, STEINERT, P. M, VIRATA, M. L. A, WAGNER, R. M, ANGST, B. D, NILLES, L. A

“…Desmoplakins (DPs) I and II are two major related proteins located in the innermost portion of the desmosomal plaque where it is thought they may play a role…”
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Overexpression of Human Loricrin in Transgenic Mice Produces a Normal Phenotype by Yoneda, Kozo, Steinert, Peter M.

“…The cornified cell envelope (CE) of terminally differentiating stratified squamous epithelial cells is a complex multiprotein assembly about 15 nm thick of…”
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The deduced sequence of the novel protransglutaminase E (TGase3) of human and mouse by IN-GYU KIM, GORMAN, J. J, SANG-CHUL PARK, SOO-IL CHUNG, STEINERT, P. M

“…At least three transglutaminases are involved in terminal differentiation events in the epidermis and its derivatives, such as the hair follicle, presumably in…”
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Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins by Hohl, D, Mehrel, T, Lichti, U, Turner, M L, Roop, D R, Steinert, P M

“…We have isolated and characterized a full-length cDNA clone encoding human loricrin. Curiously, this protein displays major differences from the recently…”
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