Search Results - "Steiner, Susanne"
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1
The Immune Checkpoint Regulator PD-L1 Is Highly Expressed in Aggressive Primary Prostate Cancer
Published in Clinical cancer research (15-04-2016)“…Therapies targeting the programmed death 1 (PD-1)/programmed death ligand 1 (PD-L1) pathway promote anti-tumor immunity and have shown promising results in…”
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Journal Article -
2
SRC Signaling Is Crucial in the Growth of Synovial Sarcoma Cells
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Synovial sarcoma is a soft-tissue malignancy characterized by a reciprocal t(X;18) translocation encoding a chimeric transcriptional modifier. Several receptor…”
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Journal Article -
3
Activation of Phosphatidylinositol-3′-kinase/AKT Signaling Is Essential in Hepatoblastoma Survival
Published in Clinical cancer research (15-07-2009)“…Purpose: Hepatoblastoma represents the most frequent malignant liver tumor in childhood. The phosphatidylinositol-3′-kinase (PI3K)/AKT pathway is crucial in…”
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Journal Article -
4
Phosphatidylinositol‐3′‐kinase/AKT signaling is essential in synovial sarcoma
Published in International journal of cancer (01-10-2011)“…Synovial sarcomas account for 5–10% of all malignant soft tissue tumors. They have been shown to express different membranous growth factor receptors, many of…”
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Journal Article -
5
ATZ11 recognizes not only Z-α1-antitrypsin-polymers and complexed forms of non-Z-α1-antitrypsin but also the von Willebrand factor
Published in PloS one (19-03-2014)“…The ATZ11 antibody has been well established for the identification of α1-anti-trypsin (AAT) molecule type PiZ (Z-AAT) in blood samples and liver tissue. In…”
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Journal Article -
6
Epidermal growth factor receptor mutations in non-small cell lung cancer influence downstream Akt, MAPK and Stat3 signaling
Published in Journal of cancer research and clinical oncology (01-05-2009)“…Purpose The efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in non-small cell lung cancer (NSCLC) has been linked to activating…”
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Journal Article -
7
Changes of Oral Trigeminal Sensitivity in Patients After Middle Ear Surgery
Published in The Laryngoscope (01-09-2007)“…Objectives: The specific aim of this study was to re‐investigate the effect of chorda tympani damage on both trigeminal sensitivity and taste ability. Study…”
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Journal Article -
8
Addressing Inappropriate Polypharmacy: Investigating Perceived Facilitators and Barriers to U.S. Pharmacists’ Ability to Recommend Deprescribing
Published 01-01-2024“…While the concurrent use of multiple prescriptions (polypharmacy) is common for those with chronic conditions, professional ownership is lacking when it comes…”
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Dissertation -
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Elevated expression of LSD1 (Lysine-specific demethylase 1) during tumour progression from pre-invasive to invasive ductal carcinoma of the breast
Published in BMC clinical pathology (24-08-2012)“…Lysine-specific demethylase1 (LSD1) is a nuclear protein which belongs to the aminooxidase-enzymes playing an important role in controlling gene expression. It…”
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Journal Article -
10
Comprehensive Pulmonary Safety Review of Inhaled Technosphere® Insulin in Patients with Diabetes Mellitus
Published in Clinical drug investigation (01-10-2020)“…Background and Objective Technosphere ® Insulin (TI), a human insulin powder for inhalation (Afrezza ® ; MannKind Corporation, Westlake Village, CA, USA), is…”
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Journal Article -
11
The Contrasting Role of the Mediator Subunit MED30 in the Progression of Bladder Cancer
Published in Anticancer research (01-12-2017)“…The Mediator complex is a key regulator of gene transcription, and several studies have demonstrated altered expression of particular subunits in diverse human…”
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Journal Article -
12
Karyopherin Alpha 2 Is an Adverse Prognostic Factor in Clear-Cell and Papillary Renal-Cell Carcinoma
Published in Clinical genitourinary cancer (01-02-2019)“…Karyopherin α2 (KPNA2) is involved in the nucleocytoplasmic transport system and is functionally involved in the pathogenesis of various solid tumors by the…”
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Journal Article -
13
The knockdown of the mediator complex subunit MED30 suppresses the proliferation and migration of renal cell carcinoma cells
Published in Annals of diagnostic pathology (01-06-2018)“…The mediator complex consists of 33 subunits and plays a central role in transcription. Studies have already described the involvement of individual subunits,…”
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Journal Article -
14
The knockdown of the Mediator complex subunit MED 15 restrains urothelial bladder cancer cells' malignancy
Published in Oncology letters (01-09-2018)“…The Mediator complex, a multi-subunit protein complex, plays an integral role in regulating transcription. Genetic alterations of the mediator subunit 15…”
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Journal Article -
15
Lysine-specific demethylase 1 is highly expressed in solitary fibrous tumors, synovial sarcomas, rhabdomyosarcomas, desmoplastic small round cell tumors, and malignant peripheral nerve sheath tumors
Published in Human pathology (01-11-2011)“…Summary Epigenetic changes including histone methylation, histone acetylation, and DNA methylation are thought to play important roles in the onset and…”
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Journal Article -
16
The knockdown of the Mediator complex subunit MED15 restrains urothelial bladder cancer cells' malignancy
Published in Oncology letters (01-09-2018)“…The Mediator complex, a multi-subunit protein complex, plays an integral role in regulating transcription. Genetic alterations of the mediator subunit 15…”
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Journal Article -
17
ATZ11 Recognizes Not Only Z-[alpha].sub.1-Antitrypsin-Polymers and Complexed Forms of Non-Z-[alpha].sub.1-Antitrypsin but Also the von Willebrand Factor
Published in PloS one (19-03-2014)“…Aims The ATZ11 antibody has been well established for the identification of [alpha].sub.1 -anti-trypsin (AAT) molecule type PiZ (Z-AAT) in blood samples and…”
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Journal Article -
18
Distinguishing medullary carcinoma of the breast from high-grade hormone receptor-negative invasive ductal carcinoma: an immunohistochemical approach
Published in Histopathology (01-06-2010)“…Flucke U, Flucke M T, Hoy L, Breuer E, Goebbels R, Rhiem K, Schmutzler R, Winzenried H, Braun M, Steiner S, Buettner R & Gevensleben H (2010) Histopathology…”
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Journal Article -
19
Immunohistochemical analysis of cytochrome C oxidase facilitates differentiation between oncocytoma and chromophobe renal cell carcinoma
Published in Applied immunohistochemistry & molecular morphology (01-01-2015)“…In this study, immunohistochemical staining pattern of cytochrome c oxidase subunit 1 (CCO1) was investigated in the differentiation of renal oncocytoma (RO)…”
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Journal Article -
20
Assessment of oral trigeminal sensitivity in humans
Published in European archives of oto-rhino-laryngology (01-05-2007)“…The aim of this prospective study was to establish a clinical test for the assessment of oral trigeminal sensitivity. Capsaicin-impregnated filter paper strips…”
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Journal Article