Search Results - "Steiner, Margaret C"

Population genetic models for the spatial spread of adaptive variants: A review in light of SARS-CoV-2 evolution by Steiner, Margaret C, Novembre, John

“…Theoretical population genetics has long studied the arrival and geographic spread of adaptive variants through the analysis of mathematical models of…”
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Drug Resistance Prediction Using Deep Learning Techniques on HIV-1 Sequence Data by Steiner, Margaret C, Gibson, Keylie M, Crandall, Keith A

“…The fast replication rate and lack of repair mechanisms of human immunodeficiency virus (HIV) contribute to its high mutation frequency, with some mutations…”
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A 28-Year History of HIV-1 Drug Resistance and Transmission in Washington, DC by Gibson, Keylie M, Steiner, Margaret C, Kassaye, Seble, Maldarelli, Frank, Grossman, Zehava, Pérez-Losada, Marcos, Crandall, Keith A

“…Washington, DC consistently has one of the highest annual rates of new HIV-1 diagnoses in the United States over the last 10 years. To guide intervention and…”
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Validation of Variant Assembly Using HAPHPIPE with Next-Generation Sequence Data from Viruses by Gibson, Keylie M, Steiner, Margaret C, Rentia, Uzma, Bendall, Matthew L, Pérez-Losada, Marcos, Crandall, Keith A

“…Next-generation sequencing (NGS) offers a powerful opportunity to identify low-abundance, intra-host viral sequence variants, yet the focus of many…”
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Corrigendum: A 28-Year History of HIV-1 Drug Resistance and Transmission in Washington, DC by Gibson, Keylie M, Steiner, Margaret C, Kassaye, Seble, Maldarelli, Frank, Grossman, Zehava, Pérez-Losada, Marcos, Crandall, Keith A

“…[This corrects the article DOI: 10.3389/fmicb.2019.00369.]…”
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The design of mapping populations: Impacts of geographic scale on genetic architecture and mapping efficacy for defense and immunity by Gloss, Andrew D., Steiner, Margaret C., Novembre, John, Bergelson, Joy

“…Genome-wide association studies (GWAS) have yielded tremendous insight into the genetic architecture of trait variation. However, the collections of loci they…”
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Locus-Specific Characterization of Human Endogenous Retrovirus Expression in Prostate, Breast, and Colon Cancers by Steiner, Margaret C, Marston, Jez L, Iñiguez, Luis P, Bendall, Matthew L, Chiappinelli, Katherine B, Nixon, Douglas F, Crandall, Keith A

“…Human endogenous retroviruses (HERV) have been implicated in a variety of diseases including cancers. Recent research implicates HERVs in epigenetic gene…”
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HAPHPIPE: Haplotype Reconstruction and Phylodynamics for Deep Sequencing of Intrahost Viral Populations by Bendall, Matthew L, Gibson, Keylie M, Steiner, Margaret C, Rentia, Uzma, Pérez-Losada, Marcos, Crandall, Keith A

“…Abstract Deep sequencing of viral populations using next-generation sequencing (NGS) offers opportunities to understand and investigate evolution, transmission…”
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