Search Results - "Steinbrecher, A."

Prediction of activity-related energy expenditure using accelerometer-derived physical activity under free-living conditions: a systematic review by Jeran, S, Steinbrecher, A, Pischon, T

“…Background/Objectives: Activity-related energy expenditure (AEE) might be an important factor in the etiology of chronic diseases. However, measurement of…”
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Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling by Giles, Daniel A, Moreno-Fernandez, Maria E, Stankiewicz, Traci E, Graspeuntner, Simon, Cappelletti, Monica, Wu, David, Mukherjee, Rajib, Chan, Calvin C, Lawson, Matthew J, Klarquist, Jared, Sünderhauf, Annika, Softic, Samir, Kahn, C Ronald, Stemmer, Kerstin, Iwakura, Yoichiro, Aronow, Bruce J, Karns, Rebekah, Steinbrecher, Kris A, Karp, Christopher L, Sheridan, Rachel, Shanmukhappa, Shiva K, Reynaud, Damien, Haslam, David B, Sina, Christian, Rupp, Jan, Hogan, Simon P, Divanovic, Senad

“…Current mouse models of nonalcoholic steatohepatitis are limited, making identification and preclinical testing of new treatments challenging. Housing mice at…”
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IL‐17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice by Harley, Isaac T.W., Stankiewicz, Traci E., Giles, Daniel A., Softic, Samir, Flick, Leah M., Cappelletti, Monica, Sheridan, Rachel, Xanthakos, Stavra A., Steinbrecher, Kris A., Sartor, R. Balfour, Kohli, Rohit, Karp, Christopher L., Divanovic, Senad

“…Inflammation plays a central pathogenic role in the pernicious metabolic and end‐organ sequelae of obesity. Among these sequelae, nonalcoholic fatty liver…”
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Systematic monitoring for detection of atrial fibrillation in patients with acute ischaemic stroke (MonDAFIS): a randomised, open-label, multicentre study by Haeusler, Karl Georg, Kirchhof, Paulus, Kunze, Claudia, Tütüncü, Serdar, Fiessler, Cornelia, Malsch, Carolin, Olma, Manuel C, Jawad-Ul-Qamar, Muhammad, Krämer, Michael, Wachter, Rolf, Michalski, Dominik, Kraft, Andrea, Rizos, Timolaos, Gröschel, Klaus, Thomalla, Götz, Nabavi, Darius G, Röther, Joachim, Laufs, Ulrich, Veltkamp, Roland, Heuschmann, Peter U, Endres, Matthias, Bauerle, Michael, Besselmann, Michael, Büttner, T, Dem, Petra, Diekmann, Jens, Dietzel, Joanna, Dziewas, Rainer, Ehrlich, Sven, Evens, Annette, Gahn, Georg, Günther, Albrecht, Hamann, Gerhard F, Hartmann, Andreas, Harvey, Karen Louise, Heidenreich, Fedor, Helberg, T, Hobohm, Carsten, Hoffmann, F, Hoffmann, Olaf, Jungehulsing, Gerhard J, Kampschulte, Eva-Maria, Kraft, Peter, Krogias, Christos, Leinisch, Elke, Maschke, Matthias, Merkelbach, Stefan, Muehler, Johannes, Niehaus, Ludwig, Nören, Gesa, Oschmann, P, Palm, Frederick, Petzold, Gabor C, Pfeiler, Larissa, Pfeilschifter, Waltraud, Prince, Marie, Ringleb, Peter, Rosenkranz, Michael, Royl, Georg, Schnabel, Renate B, Schurig, Johannes, Steinbrecher, A, Stingele, Robert, Tanislav, Christian, Tyler, Louise, Urbanek, Christian

“…Systematic electrocardiogram (ECG) monitoring improves detection of covert atrial fibrillation in stroke survivors but the effect on secondary prevention is…”
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Guanylate cyclase C reduces invasion of intestinal epithelial cells by bacterial pathogens by Amarachintha, Surya, Harmel-Laws, Eleana, Steinbrecher, Kris A.

“…The guanylate cyclase C (GC-C) receptor regulates electrolyte and water secretion into the gut following activation by the E. coli enterotoxin STa, or by…”
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Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier by Han, Xiaonan, Mann, Elizabeth, Gilbert, Shila, Guan, Yanfang, Steinbrecher, Kris A, Montrose, Marshall H, Cohen, Mitchell B

“…Guanylyl Cyclase C (GCC) signaling via uroguanylin (UGN) and guanylin activation is a critical mediator of intestinal fluid homeostasis, intestinal cell…”
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Loss of Epithelial RelA Results in Deregulated Intestinal Proliferative/Apoptotic Homeostasis and Susceptibility to Inflammation by Steinbrecher, Kris A, Harmel-Laws, Eleana, Sitcheran, Raquel, Baldwin, Albert S

“…NF-kappaB plays a central, proinflammatory role in chronic intestinal inflammation, yet recent work suggests a predominantly protective function for this…”
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Meat consumption and risk of type 2 diabetes: the Multiethnic Cohort by Steinbrecher, A, Erber, E, Grandinetti, A, Kolonel, LN, Maskarinec, G

“…Objective To examine the association of meat consumption with diabetes risk in the Hawaii component of the Multiethnic Cohort and to assess effect modification…”
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An EU Perspective on Biosafety Considerations for Plants Developed by Genome Editing and Other New Genetic Modification Techniques (nGMs) by Eckerstorfer, Michael F, Dolezel, Marion, Heissenberger, Andreas, Miklau, Marianne, Reichenbecher, Wolfram, Steinbrecher, Ricarda A, Waßmann, Friedrich

“…The question whether new genetic modification techniques (nGM) in plant development might result in non-negligible negative effects for the environment and/or…”
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Apheresis therapies for NMOSD attacks: A retrospective study of 207 therapeutic interventions by Kleiter, Ingo, Gahlen, Anna, Borisow, Nadja, Fischer, Katrin, Hellwig, Kerstin, Ruprecht, Klemens, Havla, Joachim, Aktas, Orhan, Hartung, Hans-Peter, Geis, Christian, Kleinschnitz, Christoph, Berthele, Achim, Hemmer, Bernhard, Angstwurm, Klemens, Stellmann, Jan-Patrick, Schuster, Simon, Lauda, Florian, Tumani, Hayrettin, Mayer, Christoph, Krumbholz, Markus, Zeltner, Lena, Ziemann, Ulf, Linker, Ralf, Schwab, Matthias, Marziniak, Martin, Then Bergh, Florian, Hofstadt-van Oy, Ulrich, Neuhaus, Oliver, Zettl, Uwe K, Faiss, Jürgen, Wildemann, Brigitte, Paul, Friedemann, Jarius, Sven, Trebst, Corinna, Ayzenberg, I, Bayas, A, Bellmann-Strobl, J, Bischof, F, Bittner, S, Böttcher, T, Brettschneider, J, Buttmann, M, DSouza, M, Ettrich, B, Frank, B, Gass, A, Grothe, M, Guthke, K, Haarmann, A, Habedank, E, Hoffmann, F, Hoffmann, O, Junghans, J, Kaste, M, Kaulen, B, Kermer, P, Kern, P, Klotz, L, Köhler, W, Kolesilova, E, Korsen, M, Langel, S, Lee, D.H, Liebetrau, M, Luessi, F, Marouf, W, Meister, S, Melms, A, Münch, C, Niehaus, S, Pawlitzki, M, Pellkofer, H, Puhlmann, H.U, Pul, R, Retzlaf, N, Riedlinger, A, Rommer, P, Röpke, L, Rostásy, K, Rückriem, L, Ruschil, C, Senel, M, Sieb, J.P, Sommer, C, Spreer, A, Steinbrecher, A, Tackenberg, B, Tünnerhoff, J, Veauthier, C, Walter, A, Wandinger, K.P, Warnke, C, Weissert, R, Wiendl, H, Wilke, C, Winkelmann, A, Yalachkov, Y, Young, K, Zentner, C, Zipp, F

“…OBJECTIVETo analyze whether 1 of the 2 apheresis techniques, therapeutic plasma exchange (PE) or immunoadsorption (IA), is superior in treating neuromyelitis…”
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Enhanced survival following oral and systemic Salmonella enterica serovar Typhimurium infection in polymeric immunoglobulin receptor knockout mice by Betz, Kristina J, Maier, Elizabeth A, Amarachintha, Surya, Wu, David, Karmele, Erik P, Kinder, Jeremy M, Steinbrecher, Kris A, McNeal, Monica M, Luzader, Deborah H, Hogan, Simon P, Moore, Sean R

“…Polymeric immunoglobulin receptor (pIgR) transport of secretory immunoglobulin A (SIgA) to mucosal surfaces is thought to promote gut integrity and immunity to…”
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Glycogen Synthase Kinase 3β Functions To Specify Gene-Specific, NF-κB-Dependent Transcription by Steinbrecher, Kris A., Wilson, Willie, Cogswell, Patricia C., Baldwin, Albert S.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Protease‐activated receptor‐1 impedes prostate and intestinal tumor progression in mice by Adams, G. N., Sharma, B. K., Rosenfeldt, L., Frederick, M., Flick, M. J., Witte, D. P., Mosnier, L. O., Harmel‐Laws, E., Steinbrecher, K. A., Palumbo, J. S.

“…Essentials Protease activated receptor‐1 (PAR‐1) has been proposed to drive cancer progression. Surprisingly, PAR‐1 deletion accelerated tumor progression in…”
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NF-κB RelA renders tumor-associated macrophages resistant to and capable of directly suppressing CD8+ T cells for tumor promotion by Li, Liwen, Han, Lei, Sun, Fan, Zhou, Jingjiao, Ohaegbulam, Kim C., Tang, Xudong, Zang, Xingxing, Steinbrecher, Kris A., Qu, Zhaoxia, Xiao, Gutian

“…Activation of the inflammatory transcription factor NF-κB in tumor-associated macrophages (TAMs) is assumed to contribute to tumor promotion. However, whether…”
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Guanylate cyclase C deficiency causes severe inflammation in a murine model of spontaneous colitis by Harmel-Laws, Eleana, Mann, Elizabeth A, Cohen, Mitchell B, Steinbrecher, Kris A

“…Guanylate Cyclase C (GC-C; Gucy2c) is a transmembrane receptor expressed in intestinal epithelial cells. Activation of GC-C by its secreted ligand guanylin…”
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Murine guanylate cyclase C regulates colonic injury and inflammation by Steinbrecher, Kris A, Harmel-Laws, Eleana, Garin-Laflam, Monica P, Mann, Elizabeth A, Bezerra, Lucas D, Hogan, Simon P, Cohen, Mitchell B

“…Guanylate cyclase C (GUCY2C or GC-C) and its ligands, guanylin (GUCA2A or Gn) and uroguanylin (GUCA2B or Ugn), are expressed in intestinal epithelial cells and…”
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Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice by Waddell, Amanda, Ahrens, Richard, Tsai, Yi-Ting, Sherrill, Joseph D, Denson, Lee A, Steinbrecher, Kris A, Hogan, Simon P

“…In inflammatory bowel diseases (IBDs), particularly ulcerative colitis, intestinal macrophages (MΦs), eosinophils, and the eosinophil-selective chemokine…”
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Commensal microbes drive intestinal inflammation by IL-17–producing CD4⁺ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2 by Xin, Lijun, Jiang, Tony T., Chaturvedi, Vandana, Kinder, Jeremy M., Ertelt, James M., Rowe, Jared H., Steinbrecher, Kris A., Way, Sing Sing

“…The costimulatory B7-1 (CD80)/B7-2 (CD86) molecules, along with T-cell receptor stimulation, together facilitate T-cell activation. This explains why in vivo…”
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Soy consumption is not protective against diabetes in Hawaii: the Multiethnic Cohort by Morimoto, Y, Steinbrecher, A, Kolonel, L.N, Maskarinec, G

“…Based on the hypothesis that soy consumption may improve glucose tolerance, we examined the association of soy intake with diabetes risk in the Hawaii…”
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Development and evaluation of a short 24-h food list as part of a blended dietary assessment strategy in large-scale cohort studies by Freese, J, Feller, S, Harttig, U, Kleiser, C, Linseisen, J, Fischer, B, Leitzmann, M F, Six-Merker, J, Michels, K B, Nimptsch, K, Steinbrecher, A, Pischon, T, Heuer, T, Hoffmann, I, Jacobs, G, Boeing, H, Nöthlings, U

“…Background/Objectives: The validity of dietary assessment in large-scale cohort studies has been questioned. Combining data sources for the estimation of usual…”
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