Search Results - "Steinberg, Helmut"

Insulin resistance in the vasculature by Mather, Kieren J, Steinberg, Helmut O, Baron, Alain D

“…Insulin resistance is typically defined as a reduced ability of insulin to induce glucose uptake by target tissues such as fat and skeletal muscle cells. It…”
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Screening for Coronary Artery Disease in Patients With Diabetes by Bax, Jeroen J, Young, Lawrence H, Frye, Robert L, Bonow, Robert O, Steinberg, Helmut O, Barrett, Eugene J

“…Coronary artery disease (CAD) accounts for a large fraction of the morbidity, mortality, and cost of diabetes. Recognizing this, nearly 10 years ago the…”
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Native Oxyntomodulin Has Significant Glucoregulatory Effects Independent of Weight Loss in Obese Humans With and Without Type 2 Diabetes by Shankar, Sudha S, Shankar, R Ravi, Mixson, Lori A, Miller, Deborah L, Pramanik, Barnali, O'Dowd, Amy K, Williams, Donna M, Frederick, Clay B, Beals, Chan R, Stoch, S Aubrey, Steinberg, Helmut O, Kelley, David E

“…Oxyntomodulin (OXM), an enteroendocrine hormone, causes appetite suppression, increased energy expenditure, and weight loss in obese humans via activation of…”
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Sodium-glucose cotransporter 2 inhibitors and cardiovascular outcomes by Steinberg, Helmut O.

“…Type 2 diabetes mellitus (T2DM) is associated with an elevated risk of cardiovascular (CV) morbidity and mortality. Furthermore, many patients with T2DM have…”
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2007-P: Weight Change and Intentionality of Weight Loss Relate to Mortality Risk in the Postintervention (Years 8-16) Phase of Look AHEAD by WING, RENA R., CLARK, JEANNE, ESPELAND, MARK, HILL, JAMES O., JEFFERY, ROBERT W., JOHNSON, KAREN C., KNOWLER, WILLIAM C., NEIBERG, REBECCA H., OLSON, KAYLONI, PI-SUNYER, XAVIER, STEINBERG, HELMUT O., WYATT, HOLLY

“…The health effects of weight loss in older individuals with diabetes is unclear, perhaps related to intentionality of the weight loss. Look AHEAD (LA) is a…”
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Loneliness Relates to Functional Mobility in Older Adults with Type 2 Diabetes: The Look AHEAD Study by Steinberg, Helmut O., Steptoe, Andrew, Wing, Rena R., Myers, Candice A., Knowler, William C., Johnson, Karen C., Gorin, Amy A., Espeland, Mark A., Coday, Mace, Anderson, Andrea, McCaffery, Jeanne M., Rejeski, W. Jack

“…Objective. Little is known about the impact of loneliness on physical health among elderly individuals with diabetes. Here, we examined the relationship of…”
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Interactions Between Endothelin and Nitric Oxide in the Regulation of Vascular Tone in Obesity and Diabetes by MATHER, Kieren J, LTEIF, Amale, STEINBERG, Helmut O, BARON, Alain D

“…Interactions Between Endothelin and Nitric Oxide in the Regulation of Vascular Tone in Obesity and Diabetes Kieren J. Mather 1 , Amale Lteif 1 , Helmut O…”
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Endothelin Contributes to Basal Vascular Tone and Endothelial Dysfunction in Human Obesity and Type 2 Diabetes by MATHER, Kieren J, MIRZAMOHAMMADI, Bahram, LTEIF, Amale, STEINBERG, Helmut O, BARON, Alain D

“…Endothelin Contributes to Basal Vascular Tone and Endothelial Dysfunction in Human Obesity and Type 2 Diabetes Kieren J. Mather 1 , Bahram Mirzamohammadi 1 ,…”
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Insulin secretory effect of sitagliptin: assessment with a hyperglycemic clamp combined with a meal challenge by Shankar, Sudha S, Shankar, R Ravi, Mixson, Lori A, Miller, Deborah L, Steinberg, Helmut O, Beals, Chan R, Kelley, David E

“…Sitagliptin, a dipeptidyl peptidase-IV inhibitor (DPP-4), sustains activity of the incretin hormones GLP-1 and GIP and improves hyperglycemia in Type 2…”
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Polycystic ovary syndrome is associated with endothelial dysfunction by PARADISI, Giancarlo, STEINBERG, Helmut O, HEMPFLING, Annette, CRONIN, Jessica, HOOK, Ginger, SHEPARD, Marguerite K, BARON, Alain D

“…We recently reported endothelial dysfunction as a novel cardiovascular risk factor associated with insulin resistance/obesity. Here, we tested whether…”
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The management of diabetes in everyday life study: Design and methods for a pragmatic randomized controlled trial comparing the effectiveness of text messaging versus health coaching by Bailey, James E., Surbhi, Satya, Gatwood, Justin, Butterworth, Susan, Coday, Mace, Shuvo, Sohul A., Dashputre, Ankur A., Brooks, Ian M., Binkley, Bonnie L., Riordan, Carrie Jo, Steinberg, Helmut O., Gutierrez, Mary Lou, Haley, Lauren E., Leak, Cardella L., Tolley, Elizabeth A.

“…Background African American patients with uncontrolled diabetes living in medically underserved areas need effective clinic-based interventions to improve…”
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Adipose tissue production of hepatocyte growth factor contributes to elevated serum HGF in obesity by Bell, Lauren N, Ward, Jennifer L, Degawa-Yamauchi, Mikako, Bovenkerk, Jason E, Jones, RoseMarie, Cacucci, Brenda M, Gupta, Christine E, Sheridan, Carol, Sheridan, Kevin, Shankar, Sudha S, Steinberg, Helmut O, March, Keith L, Considine, Robert V

“…Serum HGF is elevated in obese individuals. This study examined the contribution of excess adipose tissue to increased circulating HGF levels in obesity. Serum…”
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Linearity of β-cell response across the metabolic spectrum and to pharmacology: insights from a graded glucose infusion-based investigation series by Shankar, Sudha S, Shankar, R Ravi, Mixson, Lori A, Miller, Deborah L, Chung, Christopher, Cilissen, Caroline, Beals, Chan R, Stoch, S Aubrey, Steinberg, Helmut O, Kelley, David E

“…The graded glucose infusion (GGI) examines insulin secretory response patterns to continuously escalating glycemia. The current study series sought to more…”
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Free fatty acid elevation impairs insulin-mediated vasodilation and nitric oxide production by STEINBERG, H. O, PARADISI, G, HOOK, G, CROWDER, K, CRONIN, J, BARON, A. D

“…Free fatty acid elevation impairs insulin-mediated vasodilation and nitric oxide production. H O Steinberg , G Paradisi , G Hook , K Crowder , J Cronin and A D…”
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Type II diabetes abrogates sex differences in endothelial function in premenopausal women by STEINBERG, H. O, PARADISI, G, CRONIN, J, CROWDE, K, HEMPFLING, A, HOOK, G, BARON, A. D

“…Obesity is a more potent cardiovascular risk factor (CVRF) in men than in women. Because traditional CVRFs cannot fully account for this sex difference, we…”
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Early Clinical Detection of Pharmacologic Response in Insulin Action in a Nondiabetic Insulin-Resistant Population by Shankar, Sudha S., MD, Shankar, R. Ravi, MD, Railkar, Radha A., PhD, Beals, Chan R., MD, PhD, Steinberg, Helmut O., MD, Kelley, David E., MD

“…Abstract Background Insulin resistance heightens the risk for type 2 diabetes mellitus and cardiovascular disease. Amelioration of insulin resistance may…”
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Indinavir impairs endothelial function in healthy HIV-negative men by Shankar, Sudha S., Dubé, Michael P., Gorski, J. Christopher, Klaunig, James E., Steinberg, Helmut O.

“…Potent antiretroviral treatment has drastically reduced mortality in HIV-infected patients but may accelerate atherosclerotic disease, which could be partially…”
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Troglitazone Therapy Improves Endothelial Function to Near Normal Levels in Women with Polycystic Ovary Syndrome by Paradisi, Giancarlo, Steinberg, Helmut O., Shepard, Marguerite K., Hook, Ginger, Baron, Alain D.

“…Obese women with polycystic ovary syndrome (PCOS) exhibit impaired endothelial function, which is strongly and directly correlated with both testosterone…”
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Weight Loss and Vascular Function: The Good and the Unknown by Shankar, Sudha S, Steinberg, Helmut O

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Repeatability Characteristics of Simple Indices of Insulin Resistance: Implications for Research Applications by Mather, Kieren J., Hunt, A. Evay, Steinberg, Helmut O., Paradisi, Giancarlo, Hook, Ginger, Katz, Arie, Quon, Michael J., Baron, Alain D.

“…The objectives of this study were to evaluate test characteristics, such as normality of distribution, variation, and repeatability, of simple fasting measures…”
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