Search Results - "Steinberg, E"
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Circuit Architecture of VTA Dopamine Neurons Revealed by Systematic Input-Output Mapping
Published in Cell (30-07-2015)“…Dopamine (DA) neurons in the midbrain ventral tegmental area (VTA) integrate complex inputs to encode multiple signals that influence motivated behaviors via…”
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Indirect regulation of HMGB1 release by gasdermin D
Published in Nature communications (11-09-2020)“…The protein high-mobility group box 1 (HMGB1) is released into the extracellular space in response to many inflammatory stimuli, where it is a potent signaling…”
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3
Radio emission from the unbound debris of tidal disruption events
Published in Monthly notices of the Royal Astronomical Society (01-08-2019)“…ABSTRACT When a star gets too close to a supermassive black hole, it is torn apart by the tidal forces. Roughly half of the stellar mass becomes unbound and…”
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Recombinase-Driver Rat Lines: Tools, Techniques, and Optogenetic Application to Dopamine-Mediated Reinforcement
Published in Neuron (Cambridge, Mass.) (08-12-2011)“…Currently there is no general approach for achieving specific optogenetic control of genetically defined cell types in rats, which provide a powerful…”
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Diversity of transgenic mouse models for selective targeting of midbrain dopamine neurons
Published in Neuron (Cambridge, Mass.) (21-01-2015)“…Ventral tegmental area (VTA) dopamine (DA) neurons have been implicated in reward, aversion, salience, cognition, and several neuropsychiatric disorders…”
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Lipid peroxidation increases membrane tension, Piezo1 gating, and cation permeability to execute ferroptosis
Published in Current biology (10-04-2023)“…The ongoing metabolic and microbicidal pathways that support and protect cellular life generate potentially damaging reactive oxygen species (ROS). To…”
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Early Spectral Evolution of Classical Novae: Consistent Evidence for Multiple Distinct Outflows
Published in The Astrophysical journal (01-12-2020)“…The physical mechanism driving mass ejection during a nova eruption is still poorly understood. Possibilities include ejection in a single ballistic event, a…”
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Positive reinforcement mediated by midbrain dopamine neurons requires D1 and D2 receptor activation in the nucleus accumbens
Published in PloS one (01-04-2014)“…The neural basis of positive reinforcement is often studied in the laboratory using intracranial self-stimulation (ICSS), a simple behavioral model in which…”
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Reaction of Substituted Phenols with Lignin Char: Dual Oxidative and Reductive Pathways Depending on Substituents and Conditions
Published in Environmental science & technology (15-12-2020)“…Biomass chars are known to be intrinsically redox-reactive toward some organic compounds, but the mechanisms are still unclear. To address this, a char made…”
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10
Broken barriers: a new take on sepsis pathogenesis
Published in Science translational medicine (22-06-2011)“…Despite intense research into the pathogenesis of sepsis, the current therapy for this devastating syndrome is primarily supportive and mortality remains high…”
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Perceptual Learning Directs Auditory Cortical Map Reorganization through Top-Down Influences
Published in The Journal of neuroscience (03-05-2006)“…The primary sensory cortex is positioned at a confluence of bottom-up dedicated sensory inputs and top-down inputs related to higher-order sensory features,…”
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Structural foundations of optogenetics: Determinants of channelrhodopsin ion selectivity
Published in Proceedings of the National Academy of Sciences - PNAS (26-01-2016)“…The structure-guided design of chloride-conducting channelrhodopsins has illuminated mechanisms underlying ion selectivity of this remarkable family of…”
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Amygdala-Midbrain Connections Modulate Appetitive and Aversive Learning
Published in Neuron (Cambridge, Mass.) (17-06-2020)“…The central amygdala (CeA) orchestrates adaptive responses to emotional events. While CeA substrates for defensive behaviors have been studied extensively, CeA…”
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Sustainable aquaculture requires environmental‐friendly treatment strategies for fish diseases
Published in Reviews in aquaculture (01-05-2020)“…Many classical therapeutants are going to be banned in Europe, and an urgent need for alternatives is emerging. This issue can be exemplified by one major…”
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Hormetins, antioxidants and prooxidants: defining quercetin-, caffeic acid- and rosmarinic acid-mediated life extension in C. elegans
Published in Biogerontology (Dordrecht) (01-08-2011)“…Quercetin, Caffeic- and Rosmarinic acid exposure extend lifespan in Caenorhabditis elegans . This comparative study uncovers basic common and contrasting…”
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Phenol-rich fulvic acid as a water additive enhances growth, reduces stress, and stimulates the immune system of fish in aquaculture
Published in Scientific reports (08-01-2021)“…Aquaculture has become imperative to cover the demands for dietary animal protein. Simultaneously, it has to overcome prejudices from excessive use of…”
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Ignition of detonation in accreted helium envelopes
Published in Monthly notices of the Royal Astronomical Society (11-05-2018)“…Abstract Sub-Chandrasekhar CO white dwarfs accreting helium have been considered as candidates for Type Ia supernova (SNIa) progenitors since the early 1980s…”
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Modification of the chemically induced inflammation assay reveals the Janus face of a phenol rich fulvic acid
Published in Scientific reports (07-04-2022)“…Inflammation is an essential process as a reaction towards infections or wounding. Exposure to hazardous environmental pollutants can lead to chronic…”
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Surface Charge: A Key Determinant of Protein Localization and Function
Published in Cancer research (Chicago, Ill.) (15-02-2010)“…Electrostatic charge at the membrane surface has emerged as a crucial determinant of the localization and activation of many proteins containing polycationic…”
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Overlooked Risks of Biochars: Persistent Free Radicals trigger Neurotoxicity in Caenorhabditis elegans
Published in Environmental science & technology (17-07-2018)“…In recent years, biochars have gained increasing interest in mitigating climate changes and revitalizing contaminated or drained soil. Studies determining…”
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