Search Results - "Steinbeisser, Herbert"

Expression of the ALK1 family of type I BMP/ADMP receptors during gastrula stages in Xenopus embryos by Leibovich, Avi, Steinbeißer, Herbert, Fainsod, Abraham

“…Multiple members of the transforming growth factor beta (TGFβ) family of secreted factors play central inductive and patterning roles during embryogenesis…”
Get full text

Wnt-11 and Fz7 reduce cell adhesion in convergent extension by sequestration of PAPC and C-cadherin by Kraft, Bianca, Berger, Corinna D, Wallkamm, Veronika, Steinbeisser, Herbert, Wedlich, Doris

“…Wnt-11/planar cell polarity signaling polarizes mesodermal cells undergoing convergent extension during Xenopus laevis gastrulation. These shape changes…”
Get full text

Molecular basis of morphogenesis during vertebrate gastrulation by Wang, Yingqun, Steinbeisser, Herbert

“…Gastrulation is a crucial step in early embryogenesis. During gastrulation, a set of morphogenetic processes takes place leading to the establishment of the…”
Get full text

A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse by Ulmer, Bärbel, Tingler, Melanie, Kurz, Sabrina, Maerker, Markus, Andre, Philipp, Mönch, Dina, Campione, Marina, Deißler, Kirsten, Lewandoski, Mark, Thumberger, Thomas, Schweickert, Axel, Fainsod, Abraham, Steinbeißer, Herbert, Blum, Martin

“…Goosecoid (Gsc ) expression marks the primary embryonic organizer in vertebrates and beyond. While functions have been assigned during later embryogenesis, the…”
Get full text

Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart by Puskaric, Sandra, Schmitteckert, Stefanie, Mori, Alessandro D., Glaser, Anne, Schneider, Katja U., Bruneau, Benoit G., Blaschke, Rüdiger J., Steinbeisser, Herbert, Rappold, Gudrun

“…Heart formation requires a highly balanced network of transcriptional activation of genes. The homeodomain transcription factor, Shox2, is essential for the…”
Get full text

Nemo-like kinase 1 (Nlk1) and paraxial protocadherin (PAPC) cooperatively control Xenopus gastrulation through regulation of Wnt/planar cell polarity (PCP) signaling by Kumar, Rahul, Ciprianidis, Anja, Theiß, Susanne, Steinbeißer, Herbert, Kaufmann, Lilian T.

“…The Wnt/planar cell polarity (PCP) pathway directs cell migration during vertebrate gastrulation and is essential for proper embryonic development. Paraxial…”
Get full text

The centriolar satellite protein SSX2IP promotes centrosome maturation by Bärenz, Felix, Inoue, Daigo, Yokoyama, Hideki, Tegha-Dunghu, Justus, Freiss, Stephanie, Draeger, Stefanie, Mayilo, Dmytro, Cado, Ivana, Merker, Sabine, Klinger, Maren, Hoeckendorf, Burkhard, Pilz, Sahra, Hupfeld, Kerstin, Steinbeisser, Herbert, Lorenz, Holger, Ruppert, Thomas, Wittbrodt, Joachim, Gruss, Oliver J

“…Meiotic maturation in vertebrate oocytes is an excellent model system for microtubule reorganization during M-phase spindle assembly. Here, we surveyed changes…”
Get full text

Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia by Hoffmann, Sandra, Berger, Ina M., Glaser, Anne, Bacon, Claire, Li, Li, Gretz, Norbert, Steinbeisser, Herbert, Rottbauer, Wolfgang, Just, Steffen, Rappold, Gudrun

“…The heart’s rhythm is initiated and regulated by a group of specialized cells in the sinoatrial node (SAN), the primary pacemaker of the heart. Abnormalities…”
Get full text

Xenopus Pkdcc1 and Pkdcc2 Are Two New Tyrosine Kinases Involved in the Regulation of JNK Dependent Wnt/PCP Signaling Pathway by Vitorino, Marta, Silva, Ana Cristina, Inácio, José Manuel, Ramalho, José Silva, Gur, Michal, Fainsod, Abraham, Steinbeisser, Herbert, Belo, José António

“…Protein Kinase Domain Containing, Cytoplasmic (PKDCC) is a protein kinase which has been implicated in longitudinal bone growth through regulation of…”
Get full text

Dapper-1 Induces Myocardial Remodeling Through Activation of Canonical Wnt Signaling in Cardiomyocytes by Hagenmueller, Marco, Riffel, Johannes H, Bernhold, Elmar, Fan, Jingjing, Zhang, Min, Ochs, Marco, Steinbeisser, Herbert, Katus, Hugo A, Hardt, Stefan E

“…Heart failure has an increasing contribution to cardiovascular disease burden and is governed by the myocardial remodeling process. The contribution of Wnt…”
Get full text

Xenopus paraxial protocadherin has signaling functions and is involved in tissue separation by Medina, Araceli, Swain, Rajeeb K, Kuerner, Klaus-Michael, Steinbeisser, Herbert

“…Protocadherins have homophilic adhesion properties and mediate selective cell–cell adhesion and cell sorting. Knockdown of paraxial protocadherin (PAPC)…”
Get full text

Molecular dissection of Wnt3a-Frizzled8 interaction reveals essential and modulatory determinants of Wnt signaling activity by Kumar, Sumit, Žigman, Mihaela, Patel, Trushar R, Trageser, Benjamin, Gross, Julia Christina, Rahm, Karolin, Boutros, Michael, Gradl, Dietmar, Steinbeisser, Herbert, Holstein, Thomas, Stetefeld, Jörg, Özbek, Suat

“…Wnt proteins are a family of secreted signaling molecules that regulate key developmental processes in metazoans. The molecular basis of Wnt binding to…”
Get full text

Xenopus Paraxial Protocadherin regulates morphogenesis by antagonizing Sprouty by Wang, Yingqun, Janicki, Patricia, Köster, Isabelle, Berger, Corinna D, Wenzl, Christian, Grosshans, Jörg, Steinbeisser, Herbert

“…Xenopus Paraxial Protocadherin (xPAPC) has signaling functions that are essential for convergent extension (CE) movements and tissue separation during…”
Get full text

A CTG Polymorphism in the CNDP1 Gene Determines the Secretion of Serum Carnosinase in Cos-7–Transfected Cells by RIEDL, Eva, KOEPPEL, Hannes, BRINKKOETTER, Paul, STERNIK, Paula, STEINBEISSER, Herbert, SAUERHOEFER, Sibylle, JANSSEN, Bart, VAN DER WOUDE, Fokko J, YARD, Benito A

“…A CTG Polymorphism in the CNDP1 Gene Determines the Secretion of Serum Carnosinase in Cos-7–Transfected Cells Eva Riedl 1 , Hannes Koeppel 1 , Paul…”
Get full text

An Evolutionary Conserved Region in the vasa 3′UTR Targets RNA Translation to the Germ Cells in the Zebrafish by Knaut, Holger, Steinbeisser, Herbert, Schwarz, Heinz, Nüsslein-Volhard, Christiane

“…In many animals, germ cells are set aside from somatic cells early during development to give rise to sperm in males and eggs in females. One strategy to…”
Get full text

Regulation of myocardin-related transcriptional coactivators through cofactor interactions in differentiation and cancer by Brandt, Dominique T., Xu, Jianming, Steinbeisser, Herbert, Grosse, Robert

“…Transcriptional signaling networks are orchestrated and fine-tuned through multiple interactions of transcription factors with subsets of cofactors thereby…”
Get full text

The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping by Campione, M, Steinbeisser, H, Schweickert, A, Deissler, K, van Bebber, F, Lowe, L A, Nowotschin, S, Viebahn, C, Haffter, P, Kuehn, M R, Blum, M

“…Left-right asymmetry in vertebrates is controlled by activities emanating from the left lateral plate. How these signals get transmitted to the forming organs…”
Get full text

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus by Sasai, Yoshiki, Lu, Bin, Steinbeisser, Herbert, De Robertis, Eddy M

“…In Drosophila the amount of neurogenic ectoderm, from which the central nervous system (CNS) derives, is regulated by a dorsal-ventral system of positional…”
Get full text

Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/beta-catenin signaling by Swain, Rajeeb Kumar, Katoh, Masaru, Medina, Araceli, Steinbeisser, Herbert

“…Secreted Frizzled related proteins (SFRPs) are extracellular regulators of Wnt signaling. These proteins contain an N-terminal cysteine rich domain (CRD)…”
Get full text

Detection of activated Rho in fixed Xenopus tissue by Berger, Corinna D., März, Martin, Kitzing, Thomas M., Grosse, Robert, Steinbeisser, Herbert

“…Small GTPases of the Rho family are important modulators of the cytoskeleton and regulate morphogenetic cell movements during embryonic development. In the…”
Get full text