Search Results - "Steinbach, Sarah K"
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Dual roles for the Drosophila PI 4-kinase Four wheel drive in localizing Rab11 during cytokinesis
Published in The Journal of cell biology (14-12-2009)“…Successful completion of cytokinesis relies on addition of new membrane, and requires the recycling endosome regulator Rab11, which localizes to the midzone…”
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Skin-derived precursors from human subjects with Type 2 diabetes yield dysfunctional vascular smooth muscle cells
Published in Clinical science (1979) (01-08-2017)“…Objective Few methods enable molecular and cellular studies of vascular aging or Type 2 diabetes (T2D). Here, we report a new approach to studying human…”
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Essential role for Schizosaccharomyces pombe pik1 in septation
Published in PloS one (09-07-2009)“…Schizosaccharomyces pombe pik1 encodes a phosphatidylinositol 4-kinase, reported to bind Cdc4, but not Cdc4(G107S). Gene deletion revealed that pik1 is…”
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Vascular smooth muscle cell differentiation from human stem/progenitor cells
Published in Methods (San Diego, Calif.) (15-05-2016)“…•Vascular smooth muscle cells (VSMCs) can be differentiated from human pluripotent stem cells and skin-derived precursors.•Differentiation occurs in serum-free…”
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Enhanced Cardiac Differentiation of Human Cardiovascular Disease Patient-Specific Induced Pluripotent Stem Cells by Applying Unidirectional Electrical Pulses Using Aligned Electroactive Nanofibrous Scaffolds
Published in ACS applied materials & interfaces (01-03-2017)“…In the embryonic heart, electrical impulses propagate in a unidirectional manner from the sinus venosus and appear to be involved in cardiogenesis. In this…”
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Serum-free differentiation of functional human coronary-like vascular smooth muscle cells from embryonic stem cells
Published in Cardiovascular research (01-04-2013)“…Despite the diverse developmental origins of vascular smooth muscle cells (VSMCs), recent attempts to generate VSMCs from human embryonic stem cells (hESCs)…”
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Directed Differentiation of Skin-Derived Precursors Into Functional Vascular Smooth Muscle Cells
Published in Arteriosclerosis, thrombosis, and vascular biology (01-12-2011)“…OBJECTIVE—The goal of this study was to characterize the factors and conditions required for smooth muscle cell (SMC)–directed differentiation of Sox2…”
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Peptide-Mediated Disruption of Calmodulin–Cyclin E Interactions Inhibits Proliferation of Vascular Smooth Muscle Cells and Neointima Formation
Published in Circulation research (29-04-2011)“…RATIONALE:Cell cycle progression in vascular smooth muscle cells (VSMCs) is a therapeutic target for restenosis. OBJECTIVE:Having discovered that calmodulin…”
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Abstract 18445: Embryonic Origins of Vascular Progenitors in the Adult Murine Aorta
Published in Circulation (New York, N.Y.) (26-11-2013)“…Abstract only Background: The vasculature is derived from many different sources during embryonic development, including neural crest, and mesoderm of…”
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Abstract 17139: Vascular Smooth Muscle Cells Retain Cell Physiological Abnormalities as a Function of Underlying Type-2 Diabetes
Published in Circulation (New York, N.Y.) (11-11-2016)“…RationaleFew methods enable molecular and cellular studies of human vascular aging or type-2 diabetes (T2D).ObjectiveTo characterize functional responses of…”
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Abstract 17158: Somitic Mesoderm-derived and Sox2+ Stem Cells Give Rise To Sca-1+ Progenitor Cells in Mouse Aorta
Published in Circulation (New York, N.Y.) (11-11-2016)“…RationaleSca-1 progenitor cells in mouse aorta are known to generate vascular cells. However, their embryological origins and temporospatial abundance during…”
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Aortic Sca-1+ Progenitor Cells Arise from the Somitic Mesoderm Lineage in Mouse
Published in Atherosclerosis. Supplements (01-06-2018)Get full text
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