Search Results - "Stehle, John R."

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    Understanding key assay parameters that affect measurements of trastuzumab-mediated ADCC against Her2 positive breast cancer cells by Kute, Timothy, Stehle, Jr, John R., Ornelles, David, Walker, Natalie, Delbono, Osvaldo, Vaughn, James P.

    Published in Oncoimmunology (01-09-2012)
    “…Use of the antibody trastuzumab to kill HER2+ breast cancer cells is an attractive therapy because of its specificity and minimal adverse effects. However, a…”
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    Breast tumor cells isolated from in vitro resistance to trastuzumab remain sensitive to trastuzumab anti-tumor effects in vivo and to ADCC killing by Kute, Timothy E, Savage, Lori, Stehle, John R. Jr, Kim-Shapiro, Jung W, Blanks, Michael J, Wood, James, Vaughn, James P

    Published in Cancer Immunology, Immunotherapy (01-11-2009)
    “…An understanding of model systems of trastuzumab (Herceptin) resistance is of great importance since the humanized monoclonal antibody is now used as first…”
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    Detection of Measles Virus RNA in Air and Surface Specimens in a Hospital Setting by Bischoff, Werner E., McNall, Rebecca J., Blevins, Maria W., Turner, JoLyn, Lopareva, Elena N., Rota, Paul A., Stehle, John R.

    Published in The Journal of infectious diseases (15-02-2016)
    “…Measles virus (MeV) is known to be highly contagious, with an infectious period lasting from 4 days before to 4 days after rash onset. An unvaccinated, young,…”
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    The spectrum of resistance in SR/CR mice: the critical role of chemoattraction in the cancer/leukocyte interaction by Riedlinger, Gregory, Adams, Jonathan, Stehle, Jr, John R, Blanks, Michael J, Sanders, Anne M, Hicks, Amy M, Willingham, Mark C, Cui, Zheng

    Published in BMC cancer (03-05-2010)
    “…Spontaneous regression/complete resistance (SR/CR) mice are a unique colony of mice that possess an inheritable, natural cancer resistance mediated primarily…”
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    Cancer resistance of SR/CR mice in the genetic knockout backgrounds of leukocyte effector mechanisms: determinations for functional requirements by Sanders, Anne M, Stehle, Jr, John R, Blanks, Michael J, Riedlinger, Gregory, Kim-Shapiro, Jung W, Monjazeb, Arta M, Adams, Jonathan M, Willingham, Mark C, Cui, Zheng

    Published in BMC cancer (31-03-2010)
    “…Spontaneous Regression/Complete Resistant (SR/CR) mice are a colony of cancer-resistant mice that can detect and rapidly destroy malignant cells with innate…”
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    Novel innate cancer killing activity in humans by Blanks, Michael J, Stehle, Jr, John R, Du, Wei, Adams, Jonathan M, Willingham, Mark C, Allen, Glenn O, Hu, Jennifer J, Lovato, James, Molnar, Istvan, Cui, Zheng

    Published in Cancer cell international (03-08-2011)
    “…In this study, we pilot tested an in vitro assay of cancer killing activity (CKA) in circulating leukocytes of 22 cancer cases and 25 healthy controls. Using a…”
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    Impact of sex, MHC, and age of recipients on the therapeutic effect of transferred leukocytes from cancer-resistant SR/CR mice by Stehle, Jr, John R, Blanks, Michael J, Riedlinger, Gregory, Kim-Shapiro, Jung W, Sanders, Anne M, Adams, Jonathan M, Willingham, Mark C, Cui, Zheng

    Published in BMC cancer (15-09-2009)
    “…Spontaneous Regression/Complete Resistant (SR/CR) mice are resistant to cancer through a mechanism that is mediated entirely by leukocytes of innate immunity…”
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    Mass spectrometry identification of circulating alpha-1-B glycoprotein, increased in aged female C57BL/6 mice by Stehle, John R., Weeks, Mark E., Lin, Kai, Willingham, Mark C., Hicks, Amy M., Timms, John F., Cui, Zheng

    Published in Biochimica et biophysica acta (2007)
    “…In this study, we surveyed the profiles of mouse circulating proteins by 2-dimensional SDS-PAGE in different strains, sexes and ages. Among visible protein…”
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    Glycosylation of Pseudomonas aeruginosa 1244 pilin: glycan substrate specificity by DiGiandomenico, Antonio, Matewish, Mauricia J., Bisaillon, Amy, Stehle, John R., Lam, Joseph S., Castric, Peter

    Published in Molecular microbiology (01-10-2002)
    “…Summary The structural similarity between the pilin glycan and the O‐antigen of Pseudomonas aeruginosa 1244 suggested that they have a common metabolic origin…”
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    Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion by Stone, A.V, Vanderman, K.S, Willey, J.S, Long, D.L, Register, T.C, Shively, C.A, Stehle, J.R, Loeser, R.F, Ferguson, C.M

    Published in Osteoarthritis and cartilage (01-10-2015)
    “…Summary Objective Meniscus injury increases osteoarthritis risk but its pathobiology in osteoarthritis is unclear. We hypothesized that older adult vervet…”
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