Search Results - "Stehle, John R."
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Successful control of a methicillin-resistant Staphylococcus aureus outbreak in a burn intensive care unit by addition of universal decolonization with intranasal mupirocin to basic infection prevention measures
Published in American journal of infection control (01-06-2019)“…Methicillin-resistant Staphylococcus aureus (MRSA) is frequently implicated in health care–associated outbreaks in burn intensive care units, incurring…”
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Understanding key assay parameters that affect measurements of trastuzumab-mediated ADCC against Her2 positive breast cancer cells
Published in Oncoimmunology (01-09-2012)“…Use of the antibody trastuzumab to kill HER2+ breast cancer cells is an attractive therapy because of its specificity and minimal adverse effects. However, a…”
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Breast tumor cells isolated from in vitro resistance to trastuzumab remain sensitive to trastuzumab anti-tumor effects in vivo and to ADCC killing
Published in Cancer Immunology, Immunotherapy (01-11-2009)“…An understanding of model systems of trastuzumab (Herceptin) resistance is of great importance since the humanized monoclonal antibody is now used as first…”
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Lipopolysaccharide-binding protein, a surrogate marker of microbial translocation, is associated with physical function in healthy older adults
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-11-2012)“…Physical function declines, and markers of inflammation increase with advancing age, even in healthy persons. Microbial translocation (MT) is the systemic…”
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Detection of Measles Virus RNA in Air and Surface Specimens in a Hospital Setting
Published in The Journal of infectious diseases (15-02-2016)“…Measles virus (MeV) is known to be highly contagious, with an infectious period lasting from 4 days before to 4 days after rash onset. An unvaccinated, young,…”
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Age-related degenerative functional, radiographic, and histological changes of the shoulder in nonhuman primates
Published in Journal of shoulder and elbow surgery (01-08-2013)“…Background Nonhuman primates have similar shoulder anatomy and physiology compared to humans, and may represent a previously underutilized model for shoulder…”
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The spectrum of resistance in SR/CR mice: the critical role of chemoattraction in the cancer/leukocyte interaction
Published in BMC cancer (03-05-2010)“…Spontaneous regression/complete resistance (SR/CR) mice are a unique colony of mice that possess an inheritable, natural cancer resistance mediated primarily…”
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Cancer resistance of SR/CR mice in the genetic knockout backgrounds of leukocyte effector mechanisms: determinations for functional requirements
Published in BMC cancer (31-03-2010)“…Spontaneous Regression/Complete Resistant (SR/CR) mice are a colony of cancer-resistant mice that can detect and rapidly destroy malignant cells with innate…”
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Novel innate cancer killing activity in humans
Published in Cancer cell international (03-08-2011)“…In this study, we pilot tested an in vitro assay of cancer killing activity (CKA) in circulating leukocytes of 22 cancer cases and 25 healthy controls. Using a…”
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Impact of sex, MHC, and age of recipients on the therapeutic effect of transferred leukocytes from cancer-resistant SR/CR mice
Published in BMC cancer (15-09-2009)“…Spontaneous Regression/Complete Resistant (SR/CR) mice are resistant to cancer through a mechanism that is mediated entirely by leukocytes of innate immunity…”
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A nonterminal method for frequent collection of mouse circulating proteins by peritoneal lavage
Published in Analytical biochemistry (01-02-2006)Get full text
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Mass spectrometry identification of circulating alpha-1-B glycoprotein, increased in aged female C57BL/6 mice
Published in Biochimica et biophysica acta (2007)“…In this study, we surveyed the profiles of mouse circulating proteins by 2-dimensional SDS-PAGE in different strains, sexes and ages. Among visible protein…”
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Glycosylation of Pseudomonas aeruginosa 1244 pilin: glycan substrate specificity
Published in Molecular microbiology (01-10-2002)“…Summary The structural similarity between the pilin glycan and the O‐antigen of Pseudomonas aeruginosa 1244 suggested that they have a common metabolic origin…”
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Osteoarthritic changes in vervet monkey knees correlate with meniscus degradation and increased matrix metalloproteinase and cytokine secretion
Published in Osteoarthritis and cartilage (01-10-2015)“…Summary Objective Meniscus injury increases osteoarthritis risk but its pathobiology in osteoarthritis is unclear. We hypothesized that older adult vervet…”
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Age-Related Degenerative Functional, Radiographic, and Histological Changes of the Shoulder in Non-Human Primates
Published in Journal of shoulder and elbow surgery (24-01-2013)Get full text
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