Search Results - "Stegmeyer, Rebekka I."
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Conditions that promote transcellular neutrophil migration in vivo
Published in Scientific reports (24-06-2024)“…Circulating leukocytes enter tissue either through endothelial junctions (paracellular) or via a pore through the body of endothelial cells (transcellular). We…”
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Csk controls leukocyte extravasation via local regulation of Src family kinases and cortactin signaling
Published in Frontiers in immunology (28-10-2024)“…C-terminal Src kinase (Csk) targets Src family kinases (SFKs) and thereby inactivates them. We have previously shown that Csk binds to phosphorylated tyrosine…”
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Mechanosensation by endothelial PIEZO1 is required for leukocyte diapedesis
Published in Blood (21-07-2022)“…The extravasation of leukocytes is a critical step during inflammation which requires the localized opening of the endothelial barrier. This process is…”
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Platelets docking to VWF prevent leaks during leukocyte extravasation by stimulating Tie-2
Published in Blood (30-07-2020)“…Neutrophil extravasation requires opening of the endothelial barrier but does not necessarily cause plasma leakage. Leaks are prevented by contractile actin…”
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Confocal Real-Time Analysis of Cutaneous Platelet Recruitment during Immune Complex‒Mediated Inflammation
Published in Journal of investigative dermatology (01-10-2022)“…Platelets preserve vascular integrity during immune complex‒mediated skin inflammation by preventing neutrophil-provoked hemorrhage. However, the single-cell…”
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Landmark-based retrieval of inflamed skin vessels enabled by 3D correlative intravital light and volume electron microscopy
Published in Histochemistry and cell biology (01-08-2022)“…The nanometer spatial resolution of electron microscopy imaging remains an advantage over light microscopy, but the restricted field of view that can be…”
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Ubiquitination of VE-cadherin regulates inflammation-induced vascular permeability in vivo
Published in EMBO reports (07-08-2024)“…VE-cadherin is a major component of the cell adhesion machinery which provides integrity and plasticity of the barrier function of endothelial junctions. Here,…”
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