Search Results - "Stegmann, Benedikt"

Body mass index (BMI) but not body weight is associated with changes in the metabolism of risperidone; a pharmacokinetics-based hypothesis by Paulzen, Michael, Haen, Ekkehard, PhD, Stegmann, Benedikt, PhD, Hiemke, Christoph, PhD, Gründer, Gerhard, Lammertz, Sarah E., PhD, Schoretsanitis, Georgios

“…Highlights • Body weight was shown to be a pharmacokinetic irrelevant parameter for risperidone. • BMI correlated positively with active metabolite and active…”
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Effect of smoking on risperidone pharmacokinetics – A multifactorial approach to better predict the influence on drug metabolism by Schoretsanitis, Georgios, Haen, Ekkehard, Stegmann, Benedikt, Hiemke, Christoph, Gründer, Gerhard, Paulzen, Michael

“…Abstract Purpose To disentangle an association between tobacco smoking, smoking habits and pharmacokinetic patterns such as plasma concentrations of…”
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Effects of the Proton Pump Inhibitors Omeprazole and Pantoprazole on the Cytochrome P450-Mediated Metabolism of Venlafaxine by Kuzin, Maxim, Schoretsanitis, Georgios, Haen, Ekkehard, Stegmann, Benedikt, Hiemke, Christoph, Gründer, Gerhard, Paulzen, Michael

“…Background and Objective An increasing trend in prescribing proton pump inhibitors (PPIs) inevitably increases the risk of unwanted drug–drug interactions…”
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Quantification of Methylphenidate, Dexamphetamine, and Atomoxetine in Human Serum and Oral Fluid by HPLC With Fluorescence Detection by Stegmann, Benedikt, Dörfelt, Anett, Haen, Ekkehard

“…For psychostimulants, a marked individual variability in the dose-response relationship and large differences in plasma concentrations after similar doses are…”
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Blood Levels to Optimize Antipsychotic Treatment in Clinical Practice: A Joint Consensus Statement of the American Society of Clinical Psychopharmacology and the Therapeutic Drug Monitoring Task Force of the Arbeitsgemeinschaft für Neuropsychopharmakologie und Pharmakopsychiatrie by Schoretsanitis, Georgios, Kane, John M, Correll, Christoph U, Marder, Stephen R, Citrome, Leslie, Newcomer, John W, Robinson, Delbert G, Goff, Donald C, Kelly, Deanna L, Freudenreich, Oliver, Piacentino, Daria, Paulzen, Michael, Conca, Andreas, Zernig, Gerald, Haen, Ekkehard, Baumann, Pierre, Hiemke, Christoph, Gründer, Gerhard, Pharmakopsychiatrie, The Therapeutic Drug Monitoring Task Force Of The Arbeitsgemeinschaft Für Neuropsychopharmakologie Und

“…The quantification of antipsychotic levels in blood, also known as therapeutic drug monitoring (TDM), is a potentially useful tool of modern personalized…”
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Pharmacokinetics of risperidone in different application forms – Comparing long-acting injectable and oral formulations by Schoretsanitis, Georgios, de Leon, Jose, Haen, Ekkehard, Stegmann, Benedikt, Hiemke, Christoph, Gründer, Gerhard, Paulzen, Michael

“…We aimed to explore the differences in the pharmacokinetics of risperidone between oral and long-acting injectable (LAI) formulations using a large database of…”
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Clinical response in a risperidone-medicated naturalistic sample: patients’ characteristics and dose-dependent pharmacokinetic patterns by Paulzen, Michael, Haen, Ekkehard, Stegmann, Benedikt, Unterecker, Stefan, Hiemke, Christoph, Gründer, Gerhard, Schoretsanitis, Georgios

“…The purpose of this study was to disentangle an association between plasma concentrations of risperidone (RIS), its active metabolite 9-hydroxyrisperidone…”
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Cytochrome P450‐mediated interaction between perazine and risperidone: implications for antipsychotic polypharmacy by Paulzen, Michael, Haen, Ekkehard, Hiemke, Christoph, Stegmann, Benedikt, Lammertz, Sarah E., Gründer, Gerhard, Schoretsanitis, Georgios

“…Background Although clinically widespread, scientific evidence for antipsychotic polypharmacy is still limited. Combining different drugs increases the…”
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TDM in psychiatry and neurology: A comprehensive summary of the consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology, update 2017; a tool for clinicians by Schoretsanitis, Georgios, Paulzen, Michael, Unterecker, Stefan, Schwarz, Markus, Conca, Andreas, Zernig, Gerald, Gründer, Gerhard, Haen, Ekkerhard, Baumann, Pierre, Bergemann, Niels, Clement, Hans Willi, Domschke, Katharina, Eckermann, Gabriel, Egberts, Karin, Gerlach, Manfred, Greiner, Christine, Havemann-Reinecke, Ursula, Hefner, Gudrun, Helmer, Renate, Janssen, Ger, Jaquenoud-Sirot, Eveline, Laux, Gerd, Messer, Thomas, Mössner, Rainald, Müller, Matthias J., Pfuhlmann, Bruno, Riederer, Peter, Saria, Alois, Schoppek, Bernd, Silva Gracia, Margarete, Stegmann, Benedikt, Steimer, Werner, Stingl, Julia C., Uhr, Manfred, Ulrich, Sven, Waschgler, Roland, Zurek, Gabriela, Hiemke, Christoph

“…Objectives: Therapeutic drug monitoring (TDM) combines the quantification of drug concentrations in blood, pharmacological interpretation and treatment…”
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Pharmacokinetic Drug-Drug Interactions of Mood Stabilizers and Risperidone in Patients Under Combined Treatment by Schoretsanitis, Georgios, Haen, Ekkehard, Gründer, Gerhard, Stegmann, Benedikt, Schruers, Koen R J, Hiemke, Christoph, Lammertz, Sarah E, Paulzen, Michael

“…The combination of anticonvulsant mood stabilizers with antipsychotic drugs may lead to clinically relevant drug-drug interactions. The objective of the study…”
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Pharmacokinetic patterns of risperidone-associated adverse drug reactions by Schoretsanitis, Georgios, Stegmann, Benedikt, Hiemke, Christoph, Gründer, Gerhard, Schruers, Koen R. J., Walther, Sebastian, Lammertz, Sarah E., Haen, Ekkehard, Paulzen, Michael

“…Purpose The aim of the study was to investigate a correlation between plasma concentrations of risperidone (RIS), its active metabolite 9-hydroxyrisperidone…”
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Pharmacokinetic considerations in the treatment of hypertension in risperidone-medicated patients – thinking of clinically relevant CYP2D6 interactions by Paulzen, Michael, Haen, Ekkehard, Gründer, Gerhard, Lammertz, Sarah E, Stegmann, Benedikt, Schruers, Koen RJ, Walther, Sebastian, Schoretsanitis, Georgios

“…Background: Treatment of arterial hypertension in patients with severe mental illnesses often results in polypharmacy, potentially leading to drug-drug…”
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PS212. Effects of Proton Pump Inhibitors (PPI) on the Serum Concentrations of Venlafaxine by Paulzen, Michael, Gründer, Gerhard, Haen, Ekkehard, Kuzin, Maxim, Lammertz, Sarah E., Schoretsanitis, Georg, Stegmann, Benedikt

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Pharmacokinetic considerations in antipsychotic augmentation strategies: How to combine risperidone with low-potency antipsychotics by Paulzen, Michael, Schoretsanitis, Georgios, Stegmann, Benedikt, Hiemke, Christoph, Gründer, Gerhard, Schruers, Koen R.J., Walther, Sebastian, Lammertz, Sarah E., Haen, Ekkehard

“…To investigate in vivo the effect of low-potency antipsychotics on metabolism of risperidone (RIS). A therapeutic drug monitoring database containing plasma…”
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Risperidone-induced extrapyramidal side effects: is the need for anticholinergics the consequence of high plasma concentrations? by Schoretsanitis, Georgios, Haen, Ekkehard, Hiemke, Christoph, Gründer, Gerhard, Stegmann, Benedikt, Schruers, Koen R.J, Veselinovic, Tanja, Lammertz, Sarah E, Paulzen, Michael

“…Antipsychotic drugs can induce various undesirable adverse motor reactions, such as extrapyramidal side effects (EPS). A widely accepted pharmacodynamic…”
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Depressive disorders in childhood and adolescence - an analysis of KinderAGATE 2010 by Stegmann, Benedikt, Wenzel-Seifert, Katharina, Haen, Ekkehard

“…The present analysis evaluates the prevalence and medication use in inpatients with depression during childhood and adolescence at the KinderAGATE hospitals in…”
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Hyperkinetic disorders in childhood and adolescence- an analysis of KinderAGATE 2009-2012 by Stegmann, Benedikt, Rexroth, Christian A, Wenzel-Seifert, Katharina, Haen, Ekkehard

“…This contribution evaluates the prevalence, medication use as well as age and sex distribution in inpatients with hyperkinetic disorders at the KinderAGATE…”
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Erratum to: Therapeutic drug monitoring in neuropsychopharmacology : Summary of the consensus guidelines 2017 of the TDM task force of the AGNP by Unterecker, Stefan, Hefner, Gudrun, Baumann, Pierre, Gründer, Gerd, Bergemann, Niels, Clement, Hans-Willi, Conca, Andreas, Deckert, Jürgen, Domschke, Katharina, Eckermann, Gabriel, Egberts, Karin, Gerlach, Manfred, Greiner, Christine, Haen, Ekkehard, Havemann-Reinecke, Ursula, Helmer, Renate, Janssen, Ger, Jaquenoud, Eveline, Laux, Gerd, Messer, Thomas, Mössner, Rainald, Müller, Matthias J, Paulzen, Michael, Pfuhlmann, Bruno, Riederer, Peter, Saria, Alois, Schoppek, Bernd, Schoretsanitis, Georgios, Schwarz, Markus, Gracia, Margarethe Silva, Stegmann, Benedikt, Steimer, Werner, Stingl, Julia C, Uhr, Manfred, Ulrich, Sven, Waschgler, Roland, Zernig, Gerald, Zurek, Gabriele, Hiemke, Christoph

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Therapeutic drug monitoring in neuropsychopharmacology : Summary of the consensus guidelines 2017 of the TDM task force of the AGNP by Unterecker, Stefan, Hefner, Gudrun, Baumann, Pierre, Gründer, Gerd, Bergemann, Niels, Clement, Hans-Willi, Conca, Andreas, Deckert, Jürgen, Domschke, Katharina, Eckermann, Gabriel, Egberts, Karin, Gerlach, Manfred, Greiner, Christine, Haen, Ekkehard, Havemann-Reinecke, Ursula, Helmer, Renate, Janssen, Ger, Jaquenoud, Eveline, Laux, Gerd, Messer, Thomas, Mössner, Rainald, Müller, Matthias J, Paulzen, Michael, Pfuhlmann, Bruno, Riederer, Peter, Saria, Alois, Schoppek, Bernd, Schoretsanitis, Georgios, Schwarz, Markus, Gracia, Margarethe Silva, Stegmann, Benedikt, Steimer, Werner, Stingl, Julia C, Uhr, Manfred, Ulrich, Sven, Waschgler, Roland, Zernig, Gerald, Zurek, Gabriele, Hiemke, Christoph

“…Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug concentrations in blood serum or plasma to optimize pharmacological therapy…”
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Therapeutisches Drug-Monitoring in der Neuropsychopharmakologie: Zusammenfassung der Konsensusleitlinien 2017 der TDM-Arbeitsgruppe der AGNP by Unterecker, Stefan, Hefner, Gudrun, Baumann, Pierre, Gründer, Gerd, Bergemann, Niels, Clement, Hans-Willi, Conca, Andreas, Deckert, Jürgen, Domschke, Katharina, Eckermann, Gabriel, Egberts, Karin, Gerlach, Manfred, Greiner, Christine, Haen, Ekkehard, Havemann-Reinecke, Ursula, Helmer, Renate, Janssen, Ger, Jaquenoud, Eveline, Laux, Gerd, Messer, Thomas, Mössner, Rainald, Müller, Matthias J., Paulzen, Michael, Pfuhlmann, Bruno, Riederer, Peter, Saria, Alois, Schoppek, Bernd, Schoretsanitis, Georgios, Schwarz, Markus, Gracia, Margarethe Silva, Stegmann, Benedikt, Steimer, Werner, Stingl, Julia C., Uhr, Manfred, Ulrich, Sven, Waschgler, Roland, Zernig, Gerald, Zurek, Gabriele, Hiemke, Christoph

“…Zusammenfassung Therapeutisches Drug-Monitoring (TDM) umfasst die Quantifizierung und die Interpretation von Serum- oder Plasmakonzentrationen von…”
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