Search Results - "Stegman, Melanie"

Comment on Zacharia et al., A review of data about effectiveness of guidance in computer supported, inquiry based learning laboratories and simulations by Stegman, Melanie A.

“…This review is in response to “Identifying potential types of guidance for supporting student inquiry when using virtual and remote labs in science: a…”
Get full text

IPEx: A gamification tool for learner application of pharmacologic principles of opioid use, misuse, and addiction by Karpa, Kelly, Ward, Josie, Stegman, Melanie, Berg, Arthur, Leong, Shou Ling

“…Opioids are often prescribed to treat chronic pain ailments, despite lack of evidence for many conditions. Prescriptions frequently become the gateway to…”
Get full text

Identification of a Chemical That Inhibits the Mycobacterial UvrABC Complex in Nucleotide Excision Repair by Mazloum, Nayef, Stegman, Melanie A, Croteau, Deborah L, Van Houten, Bennett, Kwon, Nyoun Soo, Ling, Yan, Dickinson, Caitlyn, Venugopal, Aditya, Towheed, Mohammad Atif, Nathan, Carl

“…Bacterial DNA can be damaged by reactive nitrogen and oxygen intermediates (RNI and ROI) generated by host immunity, as well as by antibiotics that trigger…”
Get full text

A Quantification of Pathway Components Supports a Novel Model of Hedgehog Signal Transduction by Farzan, Shohreh F., Stegman, Melanie A., Ogden, Stacey K., Ascano, Manuel, Black, Kendall E., Tacchelly, Ofelia, Robbins, David J.

“…The secreted protein Hedgehog (Hh) plays a critical instructional role during metazoan development. In Drosophila, Hh signaling is interpreted by a set of…”
Get full text

Regulation of Hedgehog signaling: a complex story by Ogden, Stacey K., Ascano, Manuel, Stegman, Melanie A., Robbins, David J.

“…The Hedgehog (Hh) signal transduction pathway plays critical instructional roles during development. Activating mutations in human Hh signaling components…”
Get full text

Identification of a Functional Interaction between the Transmembrane Protein Smoothened and the Kinesin-Related Protein Costal2 by Ogden, Stacey K., Ascano, Manuel, Stegman, Melanie A., Suber, Liza M., Hooper, Joan E., Robbins, David J.

“…The hedgehog (Hh) family of morphogens plays important instructional roles in the development of numerous metazoan structures [1]. Consistent with the role Hh…”
Get full text

Immune attack players perform better on a test of cellular immunology and self confidence than their classmates who play a control video game by Stegman, Melanie

Get more information

The Kinesin-related Protein Costal2 Associates with Membranes in a Hedgehog-sensitive, Smoothened-independent Manner by Stegman, Melanie A., Goetz, John A., Ascano, Manuel, Ogden, Stacey K., Nybakken, Kent E., Robbins, David J.

“…In Drosophila, Hedgehog (Hh) signal transduction has been shown to require a multiprotein complex (Hedgehog signaling complex (HSC)), which includes the…”
Get full text

The Carboxyl-Terminal Domain of the Protein Kinase Fused Can Function as a Dominant Inhibitor of Hedgehog Signaling by Ascano, Manuel, Nybakken, Kent E., Sosinski, Janek, Stegman, Melanie A., Robbins, David J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Identification of a Tetrameric Hedgehog Signaling Complex by Stegman, Melanie A., Vallance, Jefferson E., Elangovan, Ganesh, Sosinski, Janek, Cheng, Yan, Robbins, David J.

“…Hedgehog (Hh) signal transduction requires a large cytoplasmic multi-protein complex that binds microtubules in an Hh-dependent manner. Here, we show that…”
Get full text

Biochemical fractionation of Drosophila cells by Stegman, Melanie, Robbins, David

“…This chapter describes how to perform basic biochemical fractionations of Drosophila cells, and how to begin to characterize the proteins in the resulting…”
Get more information

A philosophy of anti-infectives as a guide in the search for new drugs for tuberculosis by Nathan, Carl, Gold, Ben, Lin, Gang, Stegman, Melanie, de Carvalho, Luiz Pedro Sorio, Vandal, Omar, Venugopal, Aditya, Bryk, Ruslana

“…Summary How we develop antibiotics is shaped by how we view infectious disease. Given the urgent need for new chemotherapeutics for tuberculosis and other…”
Get full text

Students Designing Video Games about Immunology: Insights for Science Learning by Khalili, Neda, Sheridan, Kimberly, Williams, Asia, Clark, Kevin, Stegman, Melanie

“…Exposing American K-12 students to science, technology, engineering, and math (STEM) content is a national initiative. Game Design Through Mentoring and…”
Get full text

Tales of the weary regulated scaffold, Costal2 by Stegman, Melanie A

“…Hedgehog (Hh) deficient flies, mice and humans reveal a conserved developmental requirement for Hh signaling, while aberrant Hh signaling causes basal cell…”
Get full text