Search Results - "Stegman, Karen"
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Unbiased approach to identify and assess efficacy of human SARS-CoV-2 neutralizing antibodies
Published in Scientific reports (15-09-2022)“…Coronavirus disease 2019 (COVID-19) continues to significantly impact the global population, thus countermeasure platforms that enable rapid development of…”
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Chimeric mRNA-based COVID-19 vaccine induces protective immunity against Omicron and Delta variants
Published in Molecular therapy. Nucleic acids (13-12-2022)“…The emerging SARS-CoV-2 variants of concern (VOCs) exhibit enhanced transmission and immune escape, reducing the effectiveness of currently approved mRNA…”
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Olgotrelvir, a dual inhibitor of SARS-CoV-2 M pro and cathepsin L, as a standalone antiviral oral intervention candidate for COVID-19
Published in Med (New York, N.Y. : Online) (12-01-2024)“…Oral antiviral drugs with improved antiviral potency and safety are needed to address current challenges in clinical practice for treatment of COVID-19,…”
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Discovery and intranasal administration of a SARS-CoV-2 broadly acting neutralizing antibody with activity against multiple Omicron subvariants
Published in Med (New York, N.Y. : Online) (14-10-2022)“…The continual emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern, in particular the newly emerged Omicron…”
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