Search Results - "Steffens, Carolyn"

Mobility of the Human Immunodeficiency Virus (HIV) Receptor CD4 and Coreceptor CCR5 in Living Cells: Implications for HIV Fusion and Entry Events by STEFFENS, Carolyn M, HOPE, Thomas J

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Localization of CD4 and CCR5 in Living Cells by Steffens, Carolyn M, Hope, Thomas J

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Interleukin-7–treated naive T cells can be productively infected by T-cell–adapted and primary isolates of human immunodeficiency virus 1 by Steffens, Carolyn M., Managlia, Elizabeth Z., Landay, Alan, Al-Harthi, Lena

“…Although human immunodeficiency virus (HIV)gag/pol DNA can be detected in naive T cells, whether naive T cells can be productively infected by HIV is still…”
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Evaluation of thymopoiesis using T cell receptor excision circles (TRECs) : Differential correlation between adult and pediatric TRECs and naive phenotypes by STEFFENS, Carolyn M, AL-HARTHI, Lena, SHOTT, Susan, YOGEV, Ram, LANDAY, Alan

“…To determine whether the thymus is still functional despite age-related involution, we measured a biomarker for thymopoiesis known as the T cell receptor…”
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Detection of T cell receptor circles (TRECs) as biomarkers for de novo T cell synthesis using a quantitative polymerase chain reaction–enzyme linked immunosorbent assay (PCR–ELISA) by Al-Harthi, Lena, Marchetti, Giulia, Steffens, Carolyn M, Poulin, Jean-François, Sékaly, Rafick-Pierre, Landay, Alan

“…Currently, phenotypic markers that distinguish between recent thymic emigrants/de novo T cells and the rest of the peripheral T cell pool are lacking. This…”
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T cell receptor excision circle (TREC) content following maximum HIV suppression is equivalent in HIV-infected and HIV-uninfected individuals by STEFFENS, Carolyn M, SMITH, Kimberly Y, LANDAY, Alan, SHOTT, Susan, TRUCKENBROD, Allison, RUSSERT, Mary, AL-HARTHI, Lena

“…The adult human thymus contributes to de novo T cell synthesis; such synthesis can be assessed by analyzing T cell receptor excision circles (TREC). TREC…”
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Immune Reconstitution After Successful Treatment with Protease Inhibitor-Based and Protease Inhibitor-Sparing Antiretroviral Regimens by Smith, Kimberly Y, Steffens, Carolyn M, Truckenbrod, Allison, Landay, Alan, Al-Harthi, Lena

“…In a letter to the editor, Smith et al discuss the recent shift toward increased use of protease inhibitor-sparing antiretrovial regimens to limit…”
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Adoptive transfer of costimulated CD4 + T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection by Levine, Bruce L, June, Carl H, Bernstein, Wendy B, Aronson, Naomi E, Schlienger, Katia, Cotte, Julio, Perfetto, Steven, Humphries, Mary J, Ratto-Kim, Silvia, Birx, Deborah L, Steffens, Carolyn, Landay, Alan, Carroll, Richard G

“…To study the safety and feasibility of T-cell reconstitution in HIV-infected individuals, we adoptively transferred activated autologous CD4+ T cells…”
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Recent advances in the understanding of HIV accessory protein function by Steffens, C M, Hope, T J

“…In addition to the structural proteins required for viral replication, HIV expresses several additional proteins. Although these proteins are not required for…”
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Evaluation of Thymopoiesis Using T Cell Receptor Excision Circles (TRECs): Differential Correlation between Adult and Pediatric TRECs and Naı̈ve Phenotypes by Steffens, Carolyn M., Al-Harthi, Lena, Shott, Susan, Yogev, Ram, Landay, Alan

“…To determine whether the thymus is still functional despite age-related involution, we measured a biomarker for thymopoiesis known as the T cell receptor…”
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Evaluation of Thymopoiesis Using T Cell Receptor Excision Circles (TRECs): Differential Correlation between Adult and Pediatric TRECs and Naı̈ve Phenotypes by Steffens, Carolyn M., Al-Harthi, Lena, Shott, Susan, Yogev, Ram, Landay, Alan

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Thymopoiesis and HIV infection of naïve T cells: Implications for aging, HIV pathogenesis, and immune reconstitution by Steffens, Carolyn Marie

“…Recent data indicate that despite thymic involution, the adult human thymus still contributes to de novo T cell synthesis. However, the definition of a “de…”
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The human thymus: A new perspective on thymic function, aging, and hiv infection by Steffens, Carolyn M., Marchetti, Giulia, Landay, Alan, Al-Harthi, Lena

“…Shortly after birth, the human thymus begins a life long process of involution, whereby the net size of the thymus is not altered but the organ is replaced by…”
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