Search Results - "Stefanski, Eva"

Lack of group X secreted phospholipase A2 increases survival following pandemic H1N1 influenza infection by Kelvin, Alyson A, Degousee, Norbert, Banner, David, Stefanski, Eva, Leόn, Alberto J, Angoulvant, Denis, Paquette, Stéphane G, Huang, Stephen S.H, Danesh, Ali, Robbins, Clinton S, Noyan, Hossein, Husain, Mansoor, Lambeau, Gerard, Gelb, Michael, Kelvin, David J, Rubin, Barry B

“…Abstract The role of Group X secreted phospholipase A2 (GX-sPLA2 ) during influenza infection has not been previously investigated. We examined the role of…”
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Group V Phospholipase A2 in Bone Marrow-derived Myeloid Cells and Bronchial Epithelial Cells Promotes Bacterial Clearance after Escherichia coli Pneumonia by Degousee, Norbert, Kelvin, David J., Geisslinger, Gerd, Hwang, David M., Stefanski, Eva, Wang, Xing-Hua, Danesh, Ali, Angioni, Carlo, Schmidt, Helmut, Lindsay, Thomas F., Gelb, Michael H., Bollinger, James, Payré, Christine, Lambeau, Gérard, Arm, Jonathan P., Keating, Armand, Rubin, Barry B.

“…Group V-secreted phospholipase A2 (GV sPLA2) hydrolyzes bacterial phospholipids and initiates eicosanoid biosynthesis. Here, we elucidate the role of GV sPLA2…”
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Lipoproteins are substrates for human secretory group IIA phospholipase A2: preferential hydrolysis of acute phase HDL by Pruzanski, W, Stefanski, E, de Beer, F C, de Beer, M C, Vadas, P, Ravandi, A, Kuksis, A

“…Group IIA secretory phospholipase A2 is an acute phase enzyme, co-expressed with serum amyloid A protein. Both are present in atherosclerotic lesions. We…”
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MAP Kinase Kinase 6-p38 MAP Kinase Signaling Cascade Regulates Cyclooxygenase-2 Expression in Cardiac Myocytes In Vitro and In Vivo by Degousee, Norbert, Martindale, Joshua, Stefanski, Eva, Cieslak, Martin, Lindsay, Thomas F, Fish, Jason E, Marsden, Philip A, Thuerauf, Donna J, Glembotski, Christopher C, Rubin, Barry B

“…—Cyclooxygenase-2 (COX-2) catalyzes the rate-limiting step in delayed prostaglandin biosynthesis. The purpose of this study was to evaluate the role of the MAP…”
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c-Jun N-terminal Kinase-mediated Stabilization of Microsomal Prostaglandin E2 Synthase-1 mRNA Regulates Delayed Microsomal Prostaglandin E2 Synthase-1 Expression and Prostaglandin E2 Biosynthesis by Cardiomyocytes by Degousee, Norbert, Angoulvant, Denis, Fazel, Shafie, Stefanski, Eva, Saha, Sipra, Iliescu, Karina, Lindsay, Thomas F., Fish, Jason E., Marsden, Philip A., Li, Ren-Ke, Audoly, Laurent P., Jakobsson, Per-Johan, Rubin, Barry B.

“…Microsomal prostaglandin (PG) E2 synthase-1 (mPGES-1) catalyzes the terminal step in the biosynthesis of PGE2, a key proinflammatory mediator. The purpose of…”
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Inhibition of enzymatic activity of phospholipases A2 by minocycline and doxycycline by Pruzanski, W, Greenwald, R A, Street, I P, Laliberte, F, Stefanski, E, Vadas, P

“…Extracellular phospholipases A2 play an important role in articular and extra-articular inflammatory processes. Secretory non-pancreatic phospholipase A2…”
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Groups IV, V, and X Phospholipases A2s in Human Neutrophils by Degousee, Norbert, Ghomashchi, Farideh, Stefanski, Eva, Singer, Alan, Smart, Brian P., Borregaard, Niels, Reithmeier, Reinhardt, Lindsay, Thomas F., Lichtenberger, Cornelia, Reinisch, Walter, Lambeau, Gerard, Arm, Jonathan, Tischfield, Jay, Gelb, Michael H., Rubin, Barry B.

“…The bacterial tripeptide formyl-Met-Leu-Phe (fMLP) induces the secretion of enzyme(s) with phospholipase A 2 (PLA 2 ) activity from human neutrophils. We show…”
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Purification of a soluble phospholipase A2 from synovial fluid in rheumatoid arthritis by Stefanski, E, Pruzanski, W, Sternby, B, Vadas, P

“…A soluble phospholipase A2 (PLA2) was purified 4,500-fold from human rheumatoid synovial fluid. Preparative sodium dodecyl sulfate polyacrylamide gel…”
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Microsomal Prostaglandin E 2 Synthase-1 Deletion Leads to Adverse Left Ventricular Remodeling After Myocardial Infarction by Degousee, Norbert, Fazel, Shafie, Angoulvant, Denis, Stefanski, Eva, Pawelzik, Sven-Christian, Korotkova, Marina, Arab, Sara, Liu, Peter, Lindsay, Thomas F., Zhuo, Sun, Butany, Jagdish, Li, Ren-Ke, Audoly, Laurent, Schmidt, Ronald, Angioni, Carlo, Geisslinger, Gerd, Jakobsson, Per-Johan, Rubin, Barry B.

“…Background— Pharmacological inhibition of cyclooxygenase-2 increases the risk of myocardial infarction (MI) and stroke. Microsomal prostaglandin (PG) E 2…”
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Microsomal Prostaglandin E2 Synthase-1 Deletion Leads to Adverse Left Ventricular Remodeling After Myocardial Infarction by DEGOUSEE, Norbert, FAZEL, Shafie, BUTANY, Jagdish, LI, Ren-Ke, AUDOLY, Laurent, SCHMIDT, Ronald, ANGIONI, Carlo, GEISSLINGER, Gerd, JAKOBSSON, Per-Johan, RUBIN, Barry B, ANGOULVANT, Denis, STEFANSKI, Eva, PAWELZIK, Sven-Christian, KOROTKOVA, Marina, ARAB, Sara, LIU, Peter, LINDSAY, Thomas F, SUN ZHUO

“…Pharmacological inhibition of cyclooxygenase-2 increases the risk of myocardial infarction (MI) and stroke. Microsomal prostaglandin (PG) E(2) synthase-1…”
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Lack of Microsomal Prostaglandin E2 Synthase-1 in Bone Marrow―Derived Myeloid Cells Impairs Left Ventricular Function and Increases Mortality After Acute Myocardial Infarction by DEGOUSEE, Norbert, SIMPSON, Jeremy, LINDSAY, Thomas F, OFEK, Efrat, PIERRE, Sandra, BUTANY, Jagdish, JAKOBSSON, Per-Johan, KEATING, Armand, LI, Ren-Ke, NAHRENDORF, Matthias, GEISSLINGER, Gerd, BACKX, Peter H, FAZEL, Shafie, RUBIN, Barry B, SCHOLICH, Klaus, ANGOULVANT, Denis, ANGIONI, Carlo, SCHMIDT, Helmut, KOROTKOVA, Marina, STEFANSKI, Eva, WANG, Xing-Hua

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Multiple forms of phospholipase A2 in arthritic synovial fluid by Seilhamer, J J, Plant, S, Pruzanski, W, Schilling, J, Stefanski, E, Vadas, P, Johnson, L K

“…Phospholipase A2 (PLA2) has been purified to homogeneity from human arthritic synovial fluid. The activity resolved into multiple peaks by preparative HPLC…”
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Lack of Microsomal Prostaglandin E 2 Synthase-1 in Bone Marrow–Derived Myeloid Cells Impairs Left Ventricular Function and Increases Mortality After Acute Myocardial Infarction by Degousee, Norbert, Simpson, Jeremy, Fazel, Shafie, Scholich, Klaus, Angoulvant, Denis, Angioni, Carlo, Schmidt, Helmut, Korotkova, Marina, Stefanski, Eva, Wang, Xing-Hua, Lindsay, Thomas F., Ofek, Efrat, Pierre, Sandra, Butany, Jagdish, Jakobsson, Per-Johan, Keating, Armand, Li, Ren-Ke, Nahrendorf, Matthias, Geisslinger, Gerd, Backx, Peter H., Rubin, Barry B.

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Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis by Degousee, Norbert, Ghomashchi, Farideh, Stefanski, Eva, Singer, Alan, Smart, Brian P, Borregaard, Niels, Reithmeier, Reinhardt, Lindsay, Thomas F, Lichtenberger, Cornelia, Reinisch, Walter, Lambeau, Gerard, Arm, Jonathan, Tischfield, Jay, Gelb, Michael H, Rubin, Barry B

“…The bacterial tripeptide formyl-Met-Leu-Phe (fMLP) induces the secretion of enzyme(s) with phospholipase A(2) (PLA(2)) activity from human neutrophils. We show…”
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Lack of group X secreted phospholipase A sub(2) increases survival following pandemic H1N1 influenza infection by Kelvin, Alyson A, Degousee, Norbert, Banner, David, Stefanski, Eva, Le[oacgr]n, Alberto J, Angoulvant, Denis, Paquette, Stephane G, Huang, Stephen SH, Danesh, Ali, Robbins, Clinton S, Noyan, Hossein, Husain, Mansoor, Lambeau, Gerard, Gelb, Michael, Kelvin, David J, Rubin, Barry B

“…The role of Group X secreted phospholipase A sub(2) (GX-sPLA sub(2)) during influenza infection has not been previously investigated. We examined the role of…”
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Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity by Rubin, Barry B, Downey, Gregory P, Koh, Adeline, Degousee, Norbert, Ghomashchi, Farideh, Nallan, Laxman, Stefanski, Eva, Harkin, Denis W, Sun, Chunxiang, Smart, Brian P, Lindsay, Thomas F, Cherepanov, Vera, Vachon, Eric, Kelvin, David, Sadilek, Martin, Brown, Glenn E, Yaffe, Michael B, Plumb, Jonathan, Grinstein, Sergio, Glogauer, Michael, Gelb, Michael H

“…The role of a cytosolic phospholipase A(2)-alpha (cPLA(2)-alpha) in neutrophil arachidonic acid release, platelet-activating factor (PAF) biosynthesis, NADPH…”
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Lack of microsomal prostaglandin E(2) synthase-1 in bone marrow-derived myeloid cells impairs left ventricular function and increases mortality after acute myocardial infarction by Degousee, Norbert, Simpson, Jeremy, Fazel, Shafie, Scholich, Klaus, Angoulvant, Denis, Angioni, Carlo, Schmidt, Helmut, Korotkova, Marina, Stefanski, Eva, Wang, Xing-Hua, Lindsay, Thomas F, Ofek, Efrat, Pierre, Sandra, Butany, Jagdish, Jakobsson, Per-Johan, Keating, Armand, Li, Ren-Ke, Nahrendorf, Matthias, Geisslinger, Gerd, Backx, Peter H, Rubin, Barry B

“…Microsomal prostaglandin E(2) synthase-1 (mPGES-1), encoded by the Ptges gene, catalyzes prostaglandin E(2) biosynthesis and is expressed by leukocytes,…”
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Abstract 4301: Chimeric Mice Lacking Microsomal Prostaglandin E 2 Synthase-1 (mPGES) In Bone Marrow Develop Adverse Left Ventricular Remodelling After Myocardial Infarction by Rubin, Barry, Konecny, Philip, Keating, Armand, Fazel, Shafie, Wang, Xing-Hua, Angoulvant, Denis, Stefanski, Eva, Li, Ren-Ke, Lindsay, Thomas, Jakobsson, Per-Johan, Degousee, Norbert

“…Abstract only Introduction. mPGES functions downstream from COX-2 in the inducible PGE 2 biosynthetic pathway, and can be expressed by cardiac myocytes and…”
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Regulation of the cellular expression of secretory and cytosolic phospholipases A2, and cyclooxygenase-2 by peptide growth factors by Pruzanski, Waldemar, Stefanski, Eva, Vadas, Peter, Kennedy, Brian P, van den Bosch, Henk

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Mitogenic Effect of Lipoproteins on Human Vascular Smooth Muscle Cells: The Impact of Hydrolysis by gr II A Phospholipase A2 by Pruzanski, Waldemar, Stefanski, Eva, Kopilov, Julia, Kuksis, Arnis

“…Multifactorial interaction among lipoproteins, vascular wall cells, and inflammatory mediators has been recognized as the basis of atherogenesis. In the…”
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