Search Results - "Stefani C. Eames"

Transgenic zebrafish model of the C43G human insulin gene mutation by Eames, Stefani C, Kinkel, Mary D, Rajan, Sindhu, Prince, Victoria E, Philipson, Louis H

“…Aims/Introduction The human insulin gene/preproinsulin protein mutation C43G disrupts disulfide bond formation and causes diabetes in humans. Previous in vitro…”
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Intraperitoneal injection into adult zebrafish by Kinkel, Mary D, Eames, Stefani C, Philipson, Louis H, Prince, Victoria E

“…A convenient method for chemically treating zebrafish is to introduce the reagent into the tank water, where it will be taken up by the fish. However, this…”
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Blood sugar measurement in zebrafish reveals dynamics of glucose homeostasis by Eames, Stefani C, Philipson, Louis H, Prince, Victoria E, Kinkel, Mary D

“…The adult zebrafish has the potential to become an important model for diabetes-related research. To realize this potential, small-scale methods for analyzing…”
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In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes by Rajan, Sindhu, Eames, Stefani C, Park, Soo-Young, Labno, Christine, Bell, Graeme I, Prince, Victoria E, Philipson, Louis H

“…Permanent neonatal diabetes mellitus is a rare form of insulin-requiring diabetes presenting within the first few weeks or months of life. Mutations in the…”
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Cdx4 is required in the endoderm to localize the pancreas and limit beta-cell number by Kinkel, Mary D, Eames, Stefani C, Alonzo, Martha R, Prince, Victoria E

“…Cdx transcription factors have crucial roles in anteroposterior patterning of the nervous system and mesoderm. Here we focus on the role of cdx4 in patterning…”
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In Vivo Identification of a 107-Base Pair Promoter Element Mediating Neuron-Specific Expression of Mouse Gonadotropin-Releasing Hormone by Kim, Helen H, Wolfe, Andrew, Cohen, Ronald N, Eames, Stefani C, Johnson, Amanda L, Wieland, Carilyn N, Radovick, Sally

“…To identify regions of the mouse GnRH (mGnRH) promoter that mediate tissue-specific gene expression, transgenic mice have been generated with fragments of…”
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Cdx4 is required in the endoderm to localize the pancreas and limitβ -cell number by Mary D. Kinkel, Stefani C. Eames, Martha R. Alonzo, Victoria E. Prince

“…Cdx transcription factors have crucial roles in anteroposterior patterning of the nervous system and mesoderm. Here we focus on the role of cdx4 in patterning…”
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Intraperitoneal Injection into Adult Zebrafish by Kinkel, Mary D., Eames, Stefani C., Philipson, Louis H., Prince, Victoria E.

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Use of zebrafish for in vivo analysis of insulin gene mutations that cause human neonatal diabetes by Eames, Stefani C

“…Diabetes is a heterogeneous group of metabolic disorders characterized by hyperglycemia, with beta-cell dysfunction as a major contributing factor. Specific…”
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Use of zebrafish for in vivo analysis of insulin gene mutations that cause human neonatal diabetes by Eames, Stefani C

“…Diabetes is a heterogeneous group of metabolic disorders characterized by hyperglycemia, with beta-cell dysfunction as a major contributing factor. Specific…”
Get full text